摘要:
Embodiments of the invention provide a system and method for resecting a tissue mass. The system for resecting a tissue mass includes a surgical instrument and a first sensor for measuring a signal corresponding to the position and orientation of the tissue mass. The first sensor is dimensioned to fit insider or next to the tissue mass. The system also includes a second sensor attached to the surgical instrument configured to measure the position and orientation of the surgical instrument. The second sensor is configured to receive the signal from the first sensor. A controller is in communication with the first sensor and/or the second sensor, and the controller executes a stored program to calculate a distance between the first sensor and the second sensor. Accordingly, visual, auditory, haptic or other feedback is provided to the clinician to guide the surgical instrument to the surgical margin.
摘要:
Image-guide methods and apparatus for ultrasound delivery of compounds through the blood-brain barrier to selected locations in the brain target a selected location in the brain and applying ultrasound to effect in the tissues and/or fluids at that location a change detectable by imaging. At least a portion of the brain in the vicinity of the selected location is imaged, e.g., via magnetic resonance imaging, to confirm the location of that change. A compound, e.g., a neuropharmaceutical, in the patient's bloodstream is delivered to the confirmed location by applying ultrasound to effect opening of the blood-brain barrier at that location and, thereby, to induce uptake of the compound there.
摘要:
A method for modifying neuronal activity in a subject with focused ultrasound pulses (“FUP”) is provided. Such a methods is applicable for research, treatment, and diagnosis of psychiatric, neurological, and neuroendocrine disorders whose biological mechanisms include neuronal circuits in the brain. The application of focused ultrasound pulses is generally via multiple ultrasound transducers that are housed in a cap worn by the subject. The application of FUP at different tone burst duration, total sonication duration, and pulse repetition frequency settings results in either the inducement of either an increase or decrease in neuronal activity.
摘要:
A magnetic resonance imaging device is used to provide the static magnetic field for transducers. The static magnetic field in combination with electric current pulses energize phased arrayed transducers to generate acoustic waves or motion. The transducers can be arranged in the magnetic resonance imaging device static magnetic field to focus acoustic shock waves for the disintegration of target calculi in extracorporeal shock wave lithotripsy. The magnetic resonance imaging device is also used for target localization and monitoring of the mechanical energy effects of the transducers. In further embodiments, the transducers include coils that are implantable within a subject body and can be moved in the magnetic resonance imaging device's static magnetic field.
摘要:
A method for modifying neuronal activity in a subject with focused ultrasound pulses (“FUP”) is provided. Such a methods is applicable for research, treatment, and diagnosis of psychiatric, neurological, and neuroendocrine disorders whose biological mechanisms include neuronal circuits in the brain. The application of focused ultrasound pulses is generally via multiple ultrasound transducers that are housed in a cap worn by the subject. The application of FUP at different tone burst duration, total sonication duration, and pulse repetition frequency settings results in either the inducement of either an increase or decrease in neuronal activity.
摘要:
The present invention is directed to devices and systems used in magnetic imaging environments that include an actuator device having an elastomeric dielectric film with at least two electrodes, and a frame attached to the actuator device. The frame can have a plurality of configurations including, such as, for example, at least two members that can be, but not limited to, curved beams, rods, plates, or parallel beams. These rigid members can be coupled to flexible members such as, for example, links wherein the frame provides an elastic restoring force. The frame preferably provides a linear actuation force characteristic over a displacement range. The linear actuation force characteristic is defined as ±20% and preferably 10% over a displacement range. The actuator further includes a passive element disposed between the flexible members to tune a stiffness characteristic of the actuator. The passive element can be a bi-stable element. The preferred embodiment actuator includes one or more layers of the elastomeric film integrated into the frame. The elastomeric film can be made of many elastomeric materials such as, for example, but not limited to, acrylic, silicone and latex.
摘要:
The present invention describes methods for the treatment of joint diseases characterized by unwanted pannus, e.g., arthritis. The method involves the introduction of ultrasound energy into the inflamed cells or pannus of the joint to be treated resulting in destruction and/or modification of the pannus.
摘要:
Apparatus and method for generating and displaying undistorted images of a field of view containing undesirable motion and/or time varying magnetic field inhomogeneities, uses a time series of magnetic resonance (MR) image signals, corresponding to a time series of MR images, generated by a single-shot imaging technique without shot-to-shot phase encoding. Signals are stored and analyzed to identify missing and/or deteriorated images (including image portions, image lines or image line segments). Identified missing and/or deteriorated images are compensated for by replacement, repair or otherwise. MR image signals representative of a specified time series are selected. Then, selected signals of corresponding portions of the field of view are averaged. The invention may be used to present: a continuously updated time series of images; a time series of images with only a specified portions of the image updated in each display; or an entire time series of images re-created in any desired sequence.
摘要:
A virtual internal cavity inspection system non-invasively provides images of cavities of a subject from a viewpoint within the cavity. An acquisition unit acquires imaging information about internal structures of a subject. This imaging information is segmented into separate structures, and a 3D surface model is constructed. An operator views an image of the 3D model to select a goal viewpoint and a start viewpoint. A viewpoint path is created linking the start viewpoint and the goal viewpoint. Images are created with a viewpoints along the viewpoint path. A variety of additional visualization techniques aid the viewer's localization of the current image viewpoint, and its relation to the subject.