公开(公告)号：US20220401465A1

公开(公告)日：2022-12-22

申请号：US17616200

申请日：2019-06-04

Applicant: ShanghaiTech University

Inventor： Gaofeng FAN ,  Haopeng WANG ,  Yuetong WANG ,  Fei WANG

IPC: A61K31/7084 ,  A61K38/17 ,  A61K35/17 ,  A61K45/06

Abstract: Disclosed are uses of NAD+ and/or NAD+ agonists and/or NAD+ inhibitors for preparing a preparation or a kit, and a combination preparation including T cells and NAD+ and/or NAD+ agonists and/or NAD+ inhibitors. The preparation or kit is used for regulating T cell activity, regulating the expression level of CD69 on the surface of T cells, and/or regulating the phosphorylation level in T cells, and/or treating diseases related to T cell activity.