公开(公告)号：US20230329969A1

公开(公告)日：2023-10-19

申请号：US17972594

申请日：2022-10-25

申请人： Shaoda ZHANG ,  Xingyu Zheng ,  Jinhai Xian

发明人： Shaoda ZHANG ,  Xingyu Zheng ,  Jinhai Xian

IPC分类号： A61H39/08

CPC分类号： A61H39/08 ,  A61L2202/24

摘要： The invention relates to an auxiliary applicator for a biosensor, including an applicator body and a drying box, where the applicator body takes out a probe component from the drying box, and the applicator body includes: a launcher for fixing the probe component; a launching cylinder, where the launching cylinder is provided with a first elastic component, and the first elastic component is connected with the launcher, and is used to eject the launcher in a triggered state; and a needle returning component, where the needle returning component is provided with a second elastic component, and the second elastic component is simultaneously connected with the launcher and the guide needle. The invention not only reduces implantation time of the probe needle, but also speeds up withdrawal of the guide needle, thereby greatly reducing the user's pain.

公开(公告)号：US20230337368A1

公开(公告)日：2023-10-19

申请号：US17946032

申请日：2022-09-16

申请人： Shaoda ZHANG ,  Xingyu Zheng ,  Jinbao Wang

发明人： Shaoda ZHANG ,  Xingyu Zheng ,  Jinbao Wang

IPC分类号： H05K3/12 ,  C12Q1/00 ,  G01N27/30

CPC分类号： H05K3/1216 ,  C12Q1/006 ,  G01N27/308

摘要： The present disclosure discloses a method for preparing a screen-printed bioelectrochemical sensor. A conductive polymer polyaniline is deposited on a surface of a screen-printed carbon electrode by electropolymerization. The conductive polymer has strong adsorption property, and is used for immobilization of glucose oxidase, so that the long-term stability of the glucose oxidase on the carbon electrode is improved. Meanwhile, a polyethylene glycol glycidyl ether cross-linked polymer ferrocene and the glucose oxidase are used, so that the immobilization of the glucose oxidase is further strengthened. Moreover, a hydrogel outer membrane with a cross-linking effect is used, so that the stability of an electrode product is further improved, and great linearity is maintained.

公开(公告)号：US20240158826A1

公开(公告)日：2024-05-16

申请号：US18206088

申请日：2023-06-06

申请人： Shaoda ZHANG ,  Zhipeng Qiu ,  Xingyu Zheng

发明人： Shaoda ZHANG ,  Zhipeng Qiu ,  Xingyu Zheng

IPC分类号： C12Q1/00 ,  C12N9/12 ,  C12N11/14 ,  C12Q1/54

CPC分类号： C12Q1/006 ,  C12N9/1241 ,  C12N11/14 ,  C12Q1/54 ,  C12Y207/07027

摘要： The present invention discloses a preparation method of a synthetase for continuous monitoring of blood glucose. The method includes the preparation steps of step S1: hydroxylation of a glass bead; step S2: silanization of the glass bead; step S3: bonding of the glass bead to glucose; step S4: synthesis of a polymer particle on the surface of the glass bead to form a glucose synthetase; and step S5: separation of the highly specific glucose synthetase. According to the preparation method of a synthetase for continuous monitoring of blood glucose provided by the present invention, the glass bead is bonded to the glucose by activating the surface of the glass bead, and then bonded to a polymer to form the glucose synthetase. The artificial synthetase prepared by the method has low sensitivity to temperature and pH value, and can be directly used in a blood glucose electrochemical sensor.

公开(公告)号：US20230333052A1

公开(公告)日：2023-10-19

申请号：US17962549

申请日：2022-10-10

申请人： Shaoda ZHANG ,  Xingyu Zheng ,  Hongyang Cao

发明人： Shaoda ZHANG ,  Xingyu Zheng ,  Hongyang Cao

IPC分类号： G01N27/416 ,  G01N27/327

CPC分类号： G01N27/4163 ,  G01N27/3275

摘要： The present disclosure relates to a redundant electrode-based electrochemical sensor and an attenuation compensation method thereof. The redundant electrode-based electrochemical sensor includes an interface base and a probe portion. The interface base is provided with three electrical connection terminals. The probe portion is provided with a primary electrode sensor and a redundant electrode sensor. The primary electrode sensor and the redundant electrode sensor are respectively provided with a counter electrode, a working electrode, and a reference electrode, and share one counter electrode. The present disclosure realizes that an unknown measurement result of the primary electrode sensor is predicted by means of known characteristics of the redundant electrode sensor, a more accurate correction value is calculated, additional attenuation compensation does not need to be performed, and conventional empirical compensation method and attenuation curve fitting method are abandoned to avoid causing errors.