公开(公告)号：US11959891B2

公开(公告)日：2024-04-16

申请号：US16089503

申请日：2017-01-05

申请人： Shenzhen SheenviOmics Biotechnology Co., Ltd.

发明人： Ruijun Tian ,  Wendong Chen

IPC分类号： C07K1/36 ,  G01N30/06 ,  G01N30/60 ,  G01N30/89

CPC分类号： G01N30/06 ,  C07K1/36 ,  G01N30/6078 ,  G01N30/89 ,  G01N2030/065

摘要： Disclosed is a proteomics sample preparation device, comprising a pipette tip, an ion exchange resin filler and a solid-phase extraction membrane. The solid-phase extraction membrane is filled into the lower end of the pipette tip, and the ion exchange resin filler is filled into the lower end of the pipette tip and is located above the solid-phase extraction membrane. The ion exchange resin filler is a strong cation exchange resin filler or a strong anion exchange resin filler. Disclosed is a protein chromatographic separation platform comprising the proteomic reactor and a liquid chromatography-mass spectrometer. Disclosed is the use of the proteomics reactor and protein chromatographic separation platform in the protein identification and protein quantitative analysis of a cell, a tissue or a blood sample.