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公开(公告)号：US20090148524A1
公开(公告)日：2009-06-11
申请号：US12087107
申请日：2006-12-27
IPC分类号： A61K9/22 , A61K31/4184 , A61P1/04 , A61K31/4439
CPC分类号： A61K9/0056 , A61K9/2077 , A61K31/4439 , A61K47/26 , A61K47/38 , C07D401/12
摘要： It is intended to provide a method of producing a solid preparation disintegrating in the oral cavity characterized by comprising mixing fine subtilaes containing a medicinal ingredient with an additive containing δ-mannitol and tableting the mixture; and a solid preparation disintegrating in the oral cavity produced thereby. This solid preparation disintegrating in the oral cavity has such a strength (hardness) as suffering from no defect even under stresses in transporting, packaging with the use of an automated packaging machine, taking out from a PTP and soon.
摘要翻译： 旨在提供一种在口腔内制备崩解的固体制剂的方法，其特征在于包括将含有药物成分的精细细胞与含有δ-甘露糖醇的添加剂混合并将该混合物压片; 以及在由此产生的口腔中分解的固体制剂。 这种在口腔中崩解的固体制剂具有如下强度（硬度），即使在使用自动包装机从PTP中取出并且很快就能在运输，包装的应用中也没有缺陷。
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公开(公告)号：US08486450B2
公开(公告)日：2013-07-16
申请号：US12087107
申请日：2006-12-27
CPC分类号： A61K9/0056 , A61K9/2077 , A61K31/4439 , A61K47/26 , A61K47/38 , C07D401/12
摘要： It is intended to provide a method of producing a solid preparation disintegrating in the oral cavity characterized by comprising mixing fine subtilaes containing a medicinal ingredient with an additive containing δ-mannitol and tableting the mixture; and a solid preparation disintegrating in the oral cavity produced thereby. This solid preparation disintegrating in the oral cavity has such a strength (hardness) as suffering from no defect even under stresses in transporting, packaging with the use of an automated packaging machine, taking out from a PTP and soon.
摘要翻译： 旨在提供一种在口腔内制备崩解的固体制剂的方法，其特征在于包括将含有药物成分的精细细胞与含有δ-甘露糖醇的添加剂混合并将该混合物压片; 以及在由此产生的口腔中分解的固体制剂。 这种在口腔中崩解的固体制剂具有如下强度（硬度），即使在使用自动包装机从PTP中取出并且很快就能在运输，包装的应用中也没有缺陷。
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公开(公告)号：US20090148520A1
公开(公告)日：2009-06-11
申请号：US11988430
申请日：2006-07-07
申请人： Hiroaki Arima , Hiroshi Fukada , Toshihide Saito
发明人： Hiroaki Arima , Hiroshi Fukada , Toshihide Saito
IPC分类号： A61K9/20
CPC分类号： A61K9/2072 , A61J3/10
摘要： The present invention can inhibit the occurrence of defective products without increasing the hardness of a tablet even if stress is applied to the tablet on transporting it or packing it by an automatic dispensing machine or when taking it out of the PTP and besides can be put into practice easily and inexpensively to result in facilitating the improvement of the productivity. A tablet according to the present invention comprises a body portion (2) and cap portions (3) projecting from an upper and a lower surfaces (4) from the body portion (2) each in a convex shape. The cap portion (3) has a peripheral edge portion (7) a surface of which is provided with an upright angle (α) of 35 to 50 degrees with respect to the upper and lower surfaces (4) of the body portion (2) and is formed in a convex curved surface which becomes arcuate in vertical section. The cap portion (3) has its surface provided with an angle (β) of at least 20 degrees with respect to the upper and lower surfaces (4) at a position (9) recessed by a 5% length (L) of a horizontal length (D) of the body portion (2) from a peripheral edge portion of the body portion (2). The peripheral edge portion (7) has its surface connected to the surface at the mid portion (6) smoothly.
摘要翻译： 即使在片剂输送时施加压力或者通过自动点胶机进行包装或将其从PTP中取出时，本发明也可以抑制片剂的硬度的产生， 易于且廉价地进行操作，以便于提高生产率。 根据本发明的片剂包括主体部分（2）和从主体部分（2）的上表面和下表面（4）突出的凸起部分的盖部分（3）。 盖部分（3）具有周边边缘部分（7），其表面相对于主体部分（2）的上表面和下表面（4）具有35至50度的直角（α） 并且形成为在垂直截面中变成弓形的凸曲面。 帽部分（3）的表面具有相对于上表面和下表面（4）至少20度的角度（β），所述角度（β）在凹陷了水平方向的5％长度（L）的位置（9）处 主体部分（2）的长度（D）从主体部分（2）的周缘部分延伸。 周边部分（7）的表面平滑地连接在中间部分（6）的表面。
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4.发明申请公开(公告)号：US20070116764A1
公开(公告)日：2007-05-24
申请号：US10581071
申请日：2004-11-30
CPC分类号： A61K9/282 , A61J3/007 , A61K9/2072 , B41M3/00 , B41M5/0011
摘要： The present invention provides a method for treating a solid dosage form to improve the printability and abrasion resistance of a print to be produced on a surface of the solid dosage form, which includes treating the surface of the solid dosage form with a polyethylene glycol-containing aqueous solution before printing; a production method of a solid dosage form with a printed surface, which includes printing on the surface after the aforementioned treatment; and a solid dosage form having a print improved in abrasion resistance on its surface, which can be obtained by the aforementioned production method.
摘要翻译： 本发明提供了一种治疗固体剂型以提高在固体剂型表面上产生的印刷品的印刷性和耐磨性的方法，其包括用含聚乙二醇的固体剂型表面处理固体剂型 印刷前的水溶液; 具有印刷表面的固体剂型的制造方法，其包括在上述处理后在表面上印刷; 以及通过上述制造方法得到的表面耐磨损性改善的固体剂型。
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5.发明授权公开(公告)号：US09149437B2
公开(公告)日：2015-10-06
申请号：US12659630
申请日：2010-03-15
CPC分类号： A61K9/282 , A61J3/007 , A61K9/2072 , B41M3/00 , B41M5/0011
摘要： The present invention provides a method for treating a solid dosage form to improve the printability and abrasion resistance of a print to be produced on a surface of the solid dosage form, which includes treating the surface of the solid dosage form with a polyethylene glycol-containing aqueous solution before printing; a production method of a solid dosage form with a printed surface, which includes printing on the surface after the aforementioned treatment; and a solid dosage form having a print improved in abrasion resistance on its surface, which can be obtained by the aforementioned production method.
摘要翻译： 本发明提供了一种治疗固体剂型以提高在固体剂型表面上产生的印刷品的印刷性和耐磨性的方法，其包括用含聚乙二醇的固体剂型表面处理固体剂型 印刷前的水溶液; 具有印刷表面的固体剂型的制造方法，其包括在上述处理后在表面上印刷; 以及通过上述制造方法得到的表面耐磨损性改善的固体剂型。
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6.发明申请公开(公告)号：US20110014130A1
公开(公告)日：2011-01-20
申请号：US12659630
申请日：2010-03-15
CPC分类号： A61K9/282 , A61J3/007 , A61K9/2072 , B41M3/00 , B41M5/0011
摘要： The present invention provides a method for treating a solid dosage form to improve the printability and abrasion resistance of a print to be produced on a surface of the solid dosage form, which includes treating the surface of the solid dosage form with a polyethylene glycol-containing aqueous solution before printing; a production method of a solid dosage form with a printed surface, which includes printing on the surface after the aforementioned treatment; and a solid dosage form having a print improved in abrasion resistance on its surface, which can be obtained by the aforementioned production method.
摘要翻译： 本发明提供了一种治疗固体剂型以提高在固体剂型表面上产生的印刷品的印刷性和耐磨性的方法，其包括用含聚乙二醇的固体剂型表面处理固体剂型 印刷前的水溶液; 具有印刷表面的固体剂型的制造方法，其包括在上述处理后在表面上印刷; 以及通过上述制造方法得到的表面耐磨损性改善的固体剂型。
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公开(公告)号：US5292994A
公开(公告)日：1994-03-08
申请号：US997626
申请日：1992-12-28
申请人： Ikuo Kobayashi , Toshihide Saito
发明人： Ikuo Kobayashi , Toshihide Saito
CPC分类号： G10H1/24
摘要： A tone setting device for an electronic musical instrument includes a tone signal generator for generating a tone signal by operating a plurality of tone setting switches, a detection circuit for detecting particular tone setting switches operated for a tone setting and a sequence of operations of the particular tone setting switches and an operation control device for controlling an operation of the detection circuit. The tone setting device makes a setting of any of a number of tones possible with minimum number of operations of the tone setting switches.
摘要翻译： 一种用于电子乐器的音调设置装置，包括通过操作多个音调设置开关产生音调信号的音调信号发生器，用于检测为音调设置操作的特定音调设置开关的检测电路以及特定音调设置的操作顺序 音调设置开关和用于控制检测电路的操作的操作控制装置。 音调设定装置能够以色调设定开关的最少操作次数设定多个音调中的任意一个音调。
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公开(公告)号：US5221802A
公开(公告)日：1993-06-22
申请号：US706010
申请日：1991-05-28
申请人： Shinya Konishi , Toshihide Saito
发明人： Shinya Konishi , Toshihide Saito
CPC分类号： G10H1/383 , G10H2210/591 , G10H2210/596 , G10H2210/601 , G10H2210/606 , G10H2210/616
摘要： A device for detecting data of contents of accompaniment for use in an electronic musical instrument in which the detection of data representing contents of a bass accompaniment is effected independently of the detection of data representing contents of a chord accompaniment, by separately providing a first portion for indicating pitches composing a chord to be performed and a second portion for indicating the lowest pitch of a bass accompaniment pattern in a pitch indicating unit and detecting pitches indicated in the second portion. Thus, data representing contents of a bass accompaniment and data representing contents of a chord accompaniment can be separately detected, whereby the electronic musical instrument can perform a bass accompaniment independent of a chord accompaniment, and thus the variety of a performance can be increased. Further, in the device for detecting data of contents of an accompaniment, bit pattern data representing a chord to be performed as an accompaniment is generated by ORing data representing pitches of a predetermined octave-segment which correspond to pitches indicated by the pitch indicating unit in each octave-segment of the first portion, and the chord to be performed is detected by comparing the bit pattern data obtained as a result of the OR operation with bit pattern data corresponding to various chords stored in a memory, by sequentially shifting the bit pattern data obtained as the result of the OR operation, whereby even a chord in an inversion thereof can be easily and accurately detected.
摘要翻译： 一种用于检测在电子乐器中使用的伴奏内容的数据的装置，其中，通过分别提供第一部分，用于检测代表低音伴奏的内容的数据，独立于表示和弦伴奏的内容的数据的检测， 指示构成要执行的和弦的音高和用于指示音调指示单元中的低音伴奏图案的最低音调的第二部分，以及检测第二部分中指示的音高。 因此，可以分别检测表示低音伴奏的内容的数据和表示和弦伴奏的内容的数据，由此电子乐器可以独立于和弦伴奏进行低音伴奏，从而可以提高各种性能。 此外，在用于检测伴奏内容的数据的装置中，表示要作为伴奏执行的和弦的位模式数据通过将表示与由音调指示单元指示的音高相对应的预定倍频程段的音调的数据进行或运算 通过将存储在存储器中的与各种和弦相对应的位图形数据作为OR运算而获得的位图形数据与通过顺序移位位图案进行比较来检测要执行的和弦 作为OR操作的结果而获得的数据，由此即使能够容易且精确地检测其反转中的和弦。
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公开(公告)号：US5155286A
公开(公告)日：1992-10-13
申请号：US596213
申请日：1990-10-11
CPC分类号： G10H1/0008 , G10H1/36 , G10H2210/171 , Y10S84/12 , Y10S84/22
摘要： A motif performing apparatus for use in an electronic musical instrument, which effects an automatic performance of a motif only while sounds are being radiated. The motif performing apparatus is able to store information representing motifs to be played, and to read and output information representing each of the motifs, separately, while instruction units for instructing a radiation of musical sounds are operated. Accordingly, even if the operation of an instruction unit is unchanged, the performance is varied according to a pattern of the information. Further, as long as the instruction unit is operated, a plurality of musical sounds are generated automatically and sequentially according to the pattern of the information, and thus a performance can be easily effected. Furthermore, the motif performing apparatus can effect the automatic performance only while the instruction unit is operated, and therefore, the automatic performance can be stopped at any time by stopping the operation of the instruction unit, and thus the player can play the electronic musical instrument while effecting an automatic performance by operating the instruction unit.
摘要翻译： 一种用于电子乐器的主题执行装置，其仅在正在辐射声音时实现主题的自动演奏。 主题执行装置能够存储表示要播放的图案的信息，并且分别读取和输出表示每个图案的信息，同时操作指示音乐声音的指示单元。 因此，即使指令单元的操作不变，则根据信息的模式来改变性能。 此外，只要指令单元被操作，根据信息的模式自动地并且顺序生成多个音乐声音，因此可以容易地实现演奏。 此外，主体执行装置只有在指令单元被操作时才能实现自动执行，因此可以通过停止指令单元的操作来随时停止自动执行，并且因此玩家可以播放电子乐器 同时通过操作指令单元来实现自动执行。
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