公开(公告)号：US20240076596A1

公开(公告)日：2024-03-07

申请号：US18268670

申请日：2021-10-14

Applicant: Shimadzu Corporation

Inventor： Tsunehiro INOUE ,  Toyoyuki HASHIMOTO ,  Yasuko YONEDA ,  Kenji TAKUBO ,  Yoichi FUJIYAMA ,  Tomoki OHKUBO ,  Eiichi OZEKI ,  Ryogo TAKAI ,  Hiroomi GOTO ,  Sadamu TOMITA

IPC: C12M1/00 ,  C12M1/12

CPC classification number: C12M23/40 ,  C12M23/06 ,  C12M23/38 ,  C12M37/04

Abstract: A cell culture container includes: an insert member having a membrane on which a cell is seeded, the insert member defining a first inner space that functions as an anaerobic chamber; a container having an attachment/detachment portion to and from which the insert member is attachable and detachable, the container defining a second inner space that functions as an aerobic chamber; a sealing member that closes an opening of the aerobic chamber between the attachment/detachment portion and the insert member with the insert member being attached to the attachment/detachment portion; and a transfer mechanism that transfers force to the sealing member. The sealing member closes the opening in response to an input of the force from the transfer mechanism.

公开(公告)号：US20230313103A1

公开(公告)日：2023-10-05

申请号：US18022592

申请日：2021-07-07

Applicant: Shimadzu Corporation

Inventor： Tsunehiro INOUE ,  Toyoyuki HASHIMOTO ,  Yasuko YONEDA ,  Kenji TAKUBO ,  Yoichi FUJIYAMA ,  Tomoki OHKUBO ,  Eiichi OZEKI ,  Ryogo TAKAI ,  Hiroomi GOTO ,  Sadamu TOMITA

IPC: C12M1/12 ,  C12M1/00 ,  C12M1/04 ,  C12M1/34

CPC classification number: C12M25/10 ,  C12M23/38 ,  C12M23/24 ,  C12M29/00 ,  C12M41/46

Abstract: A cell culture container includes: a container body; a cell culture insert having a tubular portion and an oxygen-permeable membrane; and a lid member. The container body is provided with an opening that communicates with an interior of the container body. The tubular portion includes an upper end and a lower end, and is inserted in the opening such that the lower end is located inside the container body. The lower end side of the tubular portion is closed by the membrane. The upper end side of the tubular portion is closed by the lid member. The lid member includes a lower surface that faces toward an interior of the tubular portion. The lid member is provided with an electrode insertion port and a culture medium outlet port that each communicate with the interior of the tubular portion at the lower surface.

公开(公告)号：US20220387298A1

公开(公告)日：2022-12-08

申请号：US17704653

申请日：2022-03-25

Applicant: Shimadzu Corporation

Inventor： Shigeaki SHIBAMOTO ,  Yasuko YONEDA ,  Ryogo TAKAI ,  Kohei YAMAMOTO

IPC: A61K8/98 ,  A61Q17/00 ,  A61Q19/00

Abstract: The present invention chiefly aims to provide a novel composition for controlling indigenous bacterial flora in the skin which can enhance or improve the diversity of bacterial species in the indigenous bacterial flora in the skin relative to the condition before treatment. The present invention can include, for example, a composition (e.g., an ointment, a liquid) for controlling the diversity of bacterial species in indigenous bacterial flora in the skin, comprising an effective amount of earthworm lipids extracted from a raw earthworm (Lumbricus rubellus), and a base. The composition of the present invention is useful, for example, as a raw material for skin care products and cosmetics.