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    Instrument for inducing cytokine and method of inducing cytokine
    1.
    发明申请
    Instrument for inducing cytokine and method of inducing cytokine 审中-公开
    诱导细胞因子的方法和诱导细胞因子的方法

    公开(公告)号：US20060275328A1

    公开(公告)日：2006-12-07

    申请号：US10555069

    申请日：2004-04-26

    申请人： Shinichiro Kitahara ,  Kazuo Shinmura ,  Yoshiko Abe ,  Kiyoshi Kuriyama

    发明人： Shinichiro Kitahara ,  Kazuo Shinmura ,  Yoshiko Abe ,  Kiyoshi Kuriyama

    IPC分类号： A61K39/09 ,  A61K35/74

    CPC分类号： A61K35/744

    摘要： It is intended to provide a novel instrument for inducing a cytokine and a method of inducing a cytokine by which a cytokine can be effectively induced compared to the existing cytokine induction therapy. Namely, an instrument for inducing a cytokine which contains a hemolytic streptococcus and/or a hemolytic streptococcus-origin component and a water-insoluble carrier; and a method of inducing a cytokine by using this instrument for inducing a cytokine.

    摘要翻译： 旨在提供用于诱导细胞因子的新型仪器和诱导与现有细胞因子诱导疗法相比可以有效诱导细胞因子的细胞因子的方法。 即，用于诱导含有溶血性链球菌和/或溶血性链球菌的成分的细胞因子和水不溶性载体的仪器; 以及通过使用该仪器诱导细胞因子诱导细胞因子的方法。

    LATEX PARTICLE FOR MEASUREMENT REAGENT, COATED LATEX PARTICLE, AND MEASUREMENT REAGENT FOR IMMUNOTURBIDIMETRIC METHOD
    4.
    发明申请
    LATEX PARTICLE FOR MEASUREMENT REAGENT, COATED LATEX PARTICLE, AND MEASUREMENT REAGENT FOR IMMUNOTURBIDIMETRIC METHOD 审中-公开
    用于测量试剂的LATEX颗粒，涂层LATEX颗粒和用于免疫印迹测定方法的测量试剂

    公开(公告)号：US20140065726A1

    公开(公告)日：2014-03-06

    申请号：US14008168

    申请日：2012-03-30

    申请人： Shinichiro Kitahara ,  Yuki Takahashi

    发明人： Shinichiro Kitahara ,  Yuki Takahashi

    IPC分类号： G01N33/58

    CPC分类号： G01N33/585 ,  C08F212/08 ,  G01N33/54313 ,  C08F2/26 ,  C08F212/32 ,  C08F212/14

    摘要： An object of the present invention is to provide a latex particle for a measurement reagent with which highly sensitive measurement can be performed even in measuring a measurement sample containing a test substance in a dilute concentration.The preset invention relates to a latex particle for a measurement reagent including a copolymer obtained by copolymerizing a monomer mixture containing the following polymerizable monomers (a) to (c): (a) a polymerizable monomer having a phenyl group; (b) a polymerizable monomer having a phenyl group and a sulfonate; and (c) a polymerizable monomer having a naphthyl group, in an aqueous medium containing 7.5 to 25% by weight of C1-4 alcohol without using a surfactant.

    摘要翻译： 本发明的目的是提供一种用于测量试剂的胶乳颗粒，即使在测量含有稀释浓度的测试物质的测量样品时，也可进行高灵敏度测量。 本发明涉及一种测定试剂用胶乳颗粒，其包含通过使含有以下可聚合单体（a）至（c）的单体混合物共聚获得的共聚物：（a）具有苯基的可聚合单体; （b）具有苯基和磺酸酯的可聚合单体; 和（c）在不使用表面活性剂的情况下，在含有7.5〜25重量％的C 1-4醇的水性介质中具有萘基的聚合性单体。

    PSA ASSAY AND REAGENT THEREFOR
    5.
    发明申请
    PSA ASSAY AND REAGENT THEREFOR 审中-公开
    PSA测定及其试剂

    公开(公告)号：US20140080143A1

    公开(公告)日：2014-03-20

    申请号：US14008441

    申请日：2012-03-28

    申请人： Yuki Takahashi ,  Tomo Shimizu ,  Yasushi Nakamura ,  Shinya Nakayama ,  Shinichiro Kitahara

    发明人： Yuki Takahashi ,  Tomo Shimizu ,  Yasushi Nakamura ,  Shinya Nakayama ,  Shinichiro Kitahara

    IPC分类号： G01N33/573

    CPC分类号： G01N33/543 ,  G01N33/573 ,  G01N33/57434 ,  G01N33/577 ,  G01N2333/96433

    摘要： Provided is a method for the simple and highly accurate assay of PSA by a one-step reaction that does not use carriers having different average grain sizes. Also provided is a reagent therefor. The PSA assay method comprises sensitizing insoluble carriers having the same average grain size within a range of greater than 0.20 μm but 0.40 μm or less using two types of anti-PSA monoclonal antibodies having different epitopes that are anti-PSA monoclonal antibodies that will react with both free PSA and PSA-ACT, which is a complex of free PSA and α1-antichymotrypsin, and bringing the carriers into contact with a sample in the presence of an aggregation promoter.

    摘要翻译： 提供了通过不使用具有不同平均粒径的载体的一步反应简单且高度精确地测定PSA的方法。 还提供了一种试剂。 PSA测定方法包括使用具有不同表位的两种类型的抗PSA单克隆抗体对具有相同平均粒径的不溶性载体敏感，所述抗原单克隆抗体是抗PSA单克隆抗体，其将与 游离PSA和PSA-ACT两者均为游离PSA和α1-抗胰凝乳蛋白酶的复合物，并使载体在聚集促进剂存在下与样品接触。