Electrophotographical reproduction of a multicolor image
    1.
    发明授权
    Electrophotographical reproduction of a multicolor image 失效
    多色图像的电子照相再现

    公开(公告)号:US3976372A

    公开(公告)日:1976-08-24

    申请号:US523511

    申请日:1974-11-13

    IPC分类号: G03G15/01

    CPC分类号: G03G15/0142

    摘要: A multicolor electrophotography apparatus and method wherein a photoconductive copy sheet surface containing uniform electric charge is exposed to an original through light filter which enables one color to be recorded, is developed with colored toner to produce a copy of that color, and the sequence is repeated for each of the other colors, utilizing superimposing toner images on the same copy sheet. In a preferred embodiment a sheet carriage is adapted to hold the copy sheet at its upper edge portion and carry it only in a certain direction for example in a vertical direction whereas a developer bed on which a plurality of developer reservoirs, each containing different colored developer toners are mounted, is adapted to travel in the other direction for example in the horizontal direction. During travel of the sheet carriage in the vertical direction, the photosensitive copy sheet passes through a charge deposition station, an exposure station and a development station thereby accomplishing reproduction of an image of one specified color. These steps may be repeated in as many colors as desired, for example, with accompanying movement of the developer bed so as to position the succeeding developer reservoirs containing different colored toners in the path of the sheet carriage, to produce, in as many colors as desired, a composite color image.

    摘要翻译: 一种多色电子照相设备和方法,其中含有均匀电荷的光导复制片表面通过使得能够记录一种颜色的光过滤器暴露于原件,用彩色调色剂显影以产生该颜色的副本,并且重复该顺序 对于每种其他颜色,利用叠加的调色剂图像在相同的复印纸上。 在优选实施例中,片材托架适于将复印纸保持在其上边缘部分并且仅在例如垂直方向上的某个方向上承载,而显影剂床上具有多个显影剂储存器,每个显影剂储存器包含不同的着色显影剂 调色剂被安装成适于例如沿水平方向在另一方向上行进。 在纸张托架沿垂直方向移动期间,感光复印纸通过电荷沉积站,曝光站和显影站,从而完成一个指定颜色的图像的再现。 这些步骤可以根据需要重复许多颜色,例如伴随着显影剂床的移动,以便将包含不同颜色的调色剂的后续显影剂储存器定位在片材载体的路径中,以产生与 期望的,复合彩色图像。

    Parathyroid hormone antagonists
    3.
    发明授权
    Parathyroid hormone antagonists 失效
    PARATHYROID HORMONE ANTAGONISTS

    公开(公告)号:US5229489A

    公开(公告)日:1993-07-20

    申请号:US684391

    申请日:1991-04-12

    IPC分类号: A61K38/00 C07K14/635

    CPC分类号: C07K14/635 A61K38/00

    摘要: Peptide derivatives of the following general formula (I): Seq. ID Nos. 1-6. ##STR1## wherein AAA is deletion or Ser, BBB is deletion or Glu, CCC is deletion, Ile, Phe, Leu, cyclohexylalanine, D-alle or Lys substituted at the .epsilon.-position by C.sub.6 -C.sub.18 alkylcarbonyl group, DDD is Gly or Gln, EEE is Leu, Nle or Phe, FFF is Met, Leu or Nle, GGG is Ala, Ser, Leu, Asn, Asp or Gln, HHH is Leu, Glu or Lys, III is His, Lys or Arg, JJJ is His, Lys or Arg, Xaa is Ala modified at the carboxy terminal with an amino group, provided that CCC and DDD may independently be modified at the amino terminal by C.sub.2 -C.sub.18 alkylcarbonyl group, and that EEE is not Leu when FFF is Met, GGG is Asn, HHH is Leu, III and JJJ are His, and the salts thereof, which exhibit a potent inhibitory activity against hPTH and are useful as a therapeutic agent for treating dysbolism associated with calcium or phosphoric acid, such as hypercalcemia, osteoporosis, hyperparathyroidism, renal osteodystrophy, and the like, and other related diseases involving PTH or PTHrP.

    Parathyroid hormone antagonists
    4.
    发明授权
    Parathyroid hormone antagonists 失效
    甲状旁腺激素拮抗剂

    公开(公告)号:US5446130A

    公开(公告)日:1995-08-29

    申请号:US305799

    申请日:1994-09-13

    IPC分类号: A61K38/00 C07K14/635

    CPC分类号: C07K14/635 A61K38/00

    摘要: Peptide derivatives of the following general formula (I): ##STR1## wherein AAA is deletion or Ser, BBB is deletion or Glu, CCC is deletion, Ile, Phe, Leu, cyclohexylalanine, D-alle or Lys substituted at the .epsilon.-position by C.sub.6 --C.sub.18 alkylcarbonyl group, DDD is Gly or Gln, EEE is Leu, Nle or Phe, FFF is Met, Leu or Nle, GGG is Ala, Ser Leu, Asn, Asp or Gln, HHH is Leu, Glu or Lys, III is His, Lys or Arg, JJJ is His, Lys or Arg, Xaa is Ala modified at the carboxy terminal with an amino group, provided that CCC and DDD may independently be modified at the amino terminal by C.sub.2 --C.sub.18 alkylcarbonyl group, and that EEE is not Leu when FFF is Met, GGG is Asn, HHH is Leu, III and JJJ are His, and the salts thereof, which exhibit a potent inhibitory activity against hPTH and are useful as a therapeutic agent for treating dysbolism associated with calcium or phosphoric acid, such as hypercalcemia, osteoporosis, hyperparathyroidism, renal osteodystrophy, and the like, and other related diseases involving PTH or PTHrP.

    摘要翻译: 下列通式(I)的肽衍生物:其中AAA是缺失或Ser,BBB是缺失或Glu,CCC是缺失,Ile,Phe,Leu,环己基丙氨酸,D- 通过C 6 -C 18烷基羰基在ε-位上取代的等位基或Lys,DDD是Gly或Gln,EEE是Leu,Nle或Phe,FFF是Met,Leu或Nle,GGG是Ala,Ser Leu,Asn,Asp或Gln ,HHH是Leu,Glu或Lys,III是His,Lys或Arg,JJJ是His,Lys或Arg,Xaa是在羧基末端用氨基修饰的Ala,条件是CCC和DDD可以独立地在氨基 末端为C2-C18烷基羰基,当FFF为Met时,EEE不为Leu,GGG为Asn,HHH为Leu,III和JJJ为His及其盐,对hPTH表现出有效的抑制活性,可用作 用于治疗与钙或磷酸相关的dysbolism的治疗剂,例如高钙血症,骨质疏松症,甲状旁腺功能亢进症,肾性骨营养不良等,以及其他 涉及PTH或PTHrP的相关疾病。