摘要:
A door opening and closing device for a vehicle that can remove an object attached to operation surface of a door handle with a simpler structure is provided. The device includes a door handle 41. The door handle 41 includes a grip 44 and a deflective portion 47. The grip 44 protrudes outward and defines a space 32 between the outer surface of the door outer panel 3 and the grip 44 to allow gripping by a user. The grip includes an outer surface and an operation surface opposing to the outer surface of the door outer panel 3. The deflective portion is located at an end of the grip 44 and extends from the outer surface of the grip 44 along the outer surface of the door outer panel 13 in a direction crossing front and rear directions of the vehicle to direct air flow flowing along the outer surface of the door outer panel 3 to flow through at least the space 32 of the grip 44 to the operation surface 44a.
摘要:
A door opening and closing device for a vehicle that can remove an object attached to operation surface of a door handle with a simpler structure is provided. The device includes a door handle. The door handle includes a grip and a deflective portion. The grip protrudes outward and defines a space between the outer surface of the door outer panel and the grip to allow gripping by a user. The deflective portion is located at an end of the grip and extends from the outer surface of the grip along the outer surface of the door outer panel in a direction crossing front and rear directions of the vehicle to direct air flow flowing along the outer surface of the door outer panel to flow through at least the space of the grip to the operation surface.
摘要:
The present invention relates to a benzazepinone compound represented by the following formula (I): wherein R1 represents a C1-C6 alkyl group or halogeno C1-C6 alkyl group, R2 represents a carboxyl group which may be protected, and Y represents a group represented by the formula (II): wherein Z represents CH or a nitrogen atom, or a pharmaceutically acceptable salt thereof.
摘要:
The present invention relates to a benzazepinone compound represented by the following formula (I): wherein R1 represents a C1-C6 alkyl group or halogeno C1-C6 alkyl group, R2 represents a carboxyl group which may be protected, and Y represents a group represented by the formula (II): wherein Z represents CH or a nitrogen atom, or a pharmaceutically acceptable salt thereof.
摘要:
The present invention is directed to providing prasugrel hydrochloride or the like with a reduced content of OXTP. A method for producing prasugrel hydrochloride with a reduced content of OXTP, comprising dissolving free prasugrel containing OXTP in an inert solvent and adding hydrochloric acid optionally dropwise to the solution for reaction is also provided.
摘要:
An object of the present invention is to provide prasugrel hydrochloride with a reduced content of CATP, and the like. In the formulae, R represents a protecting group for a hydroxyl group.A method for producing prasugrel hydrochloride represented by the above formula is provided, characterized by comprising, in step (i), controlling, at low values, the temperature during the addition, optionally dropwise, of a chlorinating agent and the reaction temperature after the addition, optionally dropwise, of the chlorinating agent.
摘要:
The present invention relates to pyrazole compounds represented by the formula (I): wherein R1 represents phenyl which may be substituted, R2 represents H, halogen, alkyl, alkoxy, alkylthio, alkylsulfinyl, alkylsulfonyl or substituted amino, Q represents CH or N, R3 represents H, alkyl or amino, R4 represents the formula (II) to (V): wherein R7 represents H or alkyl, R8 represents H, alkyl or substituted amino, R9 represents H or alkyl, R12 represents H, alkyl, halogeno alkyl or substituted amino, or pharmaceutically acceptable salts thereof, and a medical composition containing the same as effective ingredient.
摘要:
A vibrational frequency adjustment device comprises, as a vibrational frequency adjustment means (22): a first conversion means (40) which is provided with an input-side rotating member (41), an output-side rotating member (42), and a one-way clutch (44) for transmitting only the rotational motion in one direction of the input-side rotating member (41) to the output-side rotating member (42) and which, by causing the input-side rotating member (41) to pivot in a reciprocating manner by a set angle by means of the reciprocating linear motion of an output shaft (10), transmits only the forward motion or the reverse motion of the input-side rotating member (41) to the output-side rotating member (42) through the one-way clutch (44) to thereby rotate the output-side rotating member (42) by a given angle; and a second conversion means (50) which converts the rotational motion of the output-side rotating member (42) into the reciprocating linear motion of a second shaft member (43).
摘要:
A vibrational frequency adjustment device comprises, as a vibrational frequency adjustment means (22): a first conversion means (40) which is provided with an input-side rotating member (41), an output-side rotating member (42), and a one-way clutch (44) for transmitting only the rotational motion in one direction of the input-side rotating member (41) to the output-side rotating member (42) and which, by causing the input-side rotating member (41) to pivot in a reciprocating manner by a set angle by means of the reciprocating linear motion of an output shaft (10), transmits only the forward motion or the reverse motion of the input-side rotating member (41) to the output-side rotating member (42) through the one-way clutch (44) to thereby rotate the output-side rotating member (42) by a given angle; and a second conversion means (50) which converts the rotational motion of the output-side rotating member (42) into the reciprocating linear motion of a second shaft member (43).
摘要:
The present invention is directed to providing prasugrel hydrochloride or the like with a reduced content of OXTP. A method for producing prasugrel hydrochloride with a reduced content of OXTP, comprising dissolving free prasugrel containing OXTP in an inert solvent and adding hydrochloric acid optionally dropwise to the solution for reaction is also provided.