公开(公告)号：US20090221564A1

公开(公告)日：2009-09-03

申请号：US12224265

申请日：2007-02-20

申请人： Shouming Wang ,  Toby Jonathan Blench ,  Frederic Marlin ,  Richard Beck ,  Roger Peter Dickinson

发明人： Shouming Wang ,  Toby Jonathan Blench ,  Frederic Marlin ,  Richard Beck ,  Roger Peter Dickinson

IPC分类号： A61K31/541 ,  C07D333/58 ,  A61K31/381 ,  C07D409/12 ,  C07D409/10 ,  A61K31/4436 ,  C07D413/10 ,  A61K31/4245 ,  A61K31/496 ,  A61K31/506 ,  C07D417/12 ,  A61K31/428 ,  A61K31/422 ,  A61K31/4196 ,  A61K31/433 ,  A61K31/497 ,  A61K31/4725 ,  C07D413/12 ,  A61K31/5377 ,  A61K31/445 ,  A61K31/44 ,  A61P9/00

CPC分类号： A61K31/381 ,  C07D333/70 ,  C07D403/04 ,  C07D403/12 ,  C07D409/04 ,  C07D409/12 ,  C07D413/04 ,  C07D413/12 ,  C07D417/04 ,  C07D417/12

摘要： Heterocyclic compounds of the formula (I) are provided: wherein ring A, ring B, R1, R2, R3, R4, Y, m, n and q are as identified herein. R1 is in particular amidino. The invention further provides particular benzothiophene compounds. Compounds of the invention may be useful as inhibitors of Factor IXa and in the therapy of cardiovascular conditions and diseases, e.g. thrombosis.

摘要翻译： 提供式（I）的杂环化合物：其中环A，环B，R 1，R 2，R 3，R 4，Y，m，n和q如本文所述。 R1特别是脒基。 本发明还提供特定的苯并噻吩化合物。 本发明的化合物可用作因子IXa的抑制剂和用于心血管疾病和疾病的治疗。 血栓形成。

公开(公告)号：US20070227635A1

公开(公告)日：2007-10-04

申请号：US11579965

申请日：2005-05-11

申请人： Frederic Marlin ,  Gerard Marino

发明人： Frederic Marlin ,  Gerard Marino

IPC分类号： C06B27/00

CPC分类号： C06B45/14 ,  B60R21/2644 ,  C06C9/00

摘要： The present invention concerns a composition for a pyrotechnic compound that can be used as a thermal fuse in a gas generator comprising a pyrotechnic charge, said pyrotechnic compound having a self-ignition temperature that is lower than that of the pyrotechnic charge of the generator so as to be capable of initiating combustion of the pyrotechnic charge in the event of abnormal heating of the generator before said pyrotechnic charge reaches its self-ignition temperature. This composition is characterized in that it can be metered out and deposited in the form of an adhesive onto any appropriate support of the generator.

摘要翻译： 本发明涉及一种烟火化合物的组合物，其可用作包含烟火药物的气体发生器中的热保险丝，所述烟火化合物的自燃温度低于发生器的烟火电荷的自燃温度，以便 在烟火充电达到其自燃温度之前，能够在发生器异常加热的情况下启动烟火装置的燃烧。 该组合物的特征在于其可以计量并以粘合剂​​的形式沉积到发生器的任何适当的支撑物上。

公开(公告)号：US20130228254A1

公开(公告)日：2013-09-05

申请号：US13821525

申请日：2011-09-15

申请人： Frederic Marlin ,  Stephane Besombes

发明人： Frederic Marlin ,  Stephane Besombes

IPC分类号： C06B23/00

CPC分类号： C06B23/007 ,  C06B21/0066 ,  C06B25/34 ,  C06B29/08 ,  C06D5/02 ,  C06D5/06

摘要： The main subject of the present invention is a solid pyrotechnic gas generator compound, the composition of which contains, expressed in weight percentages: from 60 to 70% of guanidine nitrate, from 26 to 33%, advantageously 26 to 30%, of potassium perchlorate, from 2.5 to 6% of at least one combustion modifier chosen from transition metal oxides, the precursors of such oxides and mixtures thereof, from 0 to 6% of at least one additive, and does not contain an explosive ingredient. Such a compound is particularly effective for the inflation of side airbags.

摘要翻译： 本发明的主要目标是固体烟火发生剂化合物，其组合物含有以重量百分比表示：硝酸胍的60至70％，高氯酸钾的26至33％，有利的为26至30％ ，2.5至6％的至少一种选自过渡金属氧化物的燃烧改性剂，这种氧化物的前体及其混合物，0至6％的至少一种添加剂，并且不含有爆炸性成分。 这种化合物对于侧面安全气囊的充气特别有效。

公开(公告)号：US20110041969A1

公开(公告)日：2011-02-24

申请号：US12598323

申请日：2008-04-30

申请人： Frederic Marlin ,  Bernard Thibieroz

发明人： Frederic Marlin ,  Bernard Thibieroz

IPC分类号： C06B45/10 ,  C06B21/00

CPC分类号： C06D5/06 ,  C06B29/22 ,  C06B45/10

摘要： The present invention provides pyrotechnic gas generator compounds and a method of obtaining them. Said compounds have a composition which comprises: an oxidizing charge which comprises at least one inorganic perchlorate and which does not comprise a chlorine scavenger; and a crosslinked, oxygen-containing hydrocarbon binder obtained by crosslinking an elastomer in the presence of at least one crosslinking agent and at least one oxygen-containing plasticizer for said elastomer; said elastomer having a molecular weight of more than 200 000 and being preferably selected from polyesters and polyacrylates; said at least one oxygen-containing plasticizer being composed of a plasticizer of which the molecular weight is greater than 350 g/mol and the oxygen balance equal to or greater than −230 %, of a mixture of such plasticizers with one another or of a mixture of at least one such plasticizer with at least one other oxygen-containing plasticizer. Said compounds can be obtained continuously by extrusion.

摘要翻译： 本发明提供了烟火发生器化合物及其获得方法。 所述化合物具有包含：包含至少一种无机高氯酸盐并且不包含氯清除剂的氧化电荷的组合物; 以及交联的含氧烃粘合剂，其通过在至少一种交联剂和至少一种用于所述弹性体的含氧增塑剂的存在下交联弹性体而获得; 所述弹性体的分子量大于200000，优选选自聚酯和聚丙烯酸酯; 所述至少一种含氧增塑剂由分子量大于350g / mol的增塑剂和氧平衡等于或大于-230％的这种增塑剂彼此的混合物或 至少一种这样的增塑剂与至少一种其它含氧增塑剂的混合物。 所述化合物可以通过挤出连续获得。

公开(公告)号：US08029630B2

公开(公告)日：2011-10-04

申请号：US11579965

申请日：2005-05-11

申请人： Frederic Marlin ,  Gerard Marino

发明人： Frederic Marlin ,  Gerard Marino

IPC分类号： C06B45/10 ,  C06B29/02 ,  C06B45/12

CPC分类号： C06B45/14 ,  B60R21/2644 ,  C06C9/00

摘要： The present invention concerns a composition for a pyrotechnic compound that can be used as a thermal fuse in a gas generator comprising a pyrotechnic charge, said pyrotechnic compound having a self-ignition temperature that is lower than that of the pyrotechnic charge of the generator so as to be capable of initiating combustion of the pyrotechnic charge in the event of abnormal heating of the generator before said pyrotechnic charge reaches its self-ignition temperature. This composition is characterized in that it can be metered out and deposited in the form of an adhesive onto any appropriate support of the generator.

摘要翻译： 本发明涉及一种烟火化合物的组合物，其可用作包含烟火药物的气体发生器中的热保险丝，所述烟火化合物的自燃温度低于发生器的烟火电荷的自燃温度，以便 在烟火充电达到其自燃温度之前，能够在发生器异常加热的情况下启动烟火装置的燃烧。 该组合物的特征在于其可以计量并以粘合剂​​的形式沉积到发生器的任何适当的支撑物上。