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1.
公开(公告)号:US20150290136A1
公开(公告)日:2015-10-15
申请号:US14646569
申请日:2013-02-28
IPC分类号: A61K9/16
CPC分类号: A61K9/1635 , C08F220/14 , C08F220/34 , C08F2220/1825 , C08K5/05 , C08K5/09 , C08L33/14
摘要: The invention discloses a process for preparing granulated product from a powder composition comprising the mixed components (a) and (b) and (c) or (d) or both, with (a), a copolymer consisting of free-radical-polymerized C1- to C4-esters of acrylic or methacrylic acid and alkyl(meth)acrylate monomers with tertiary amino groups in the alkyl side groups (b) 5 to 25% by weight, based on (a), of a C12- to C18-monocarboxylic acid or a C12- to C18-alcohol, (c) 0 to 10% by weight based on (a) of a dicarboxylic acid having 3 to 10 carbon atoms, (d) 0 to 20% by weight, based on (a), of an emulsifier having an HLB of at least 14, wherein the mixed components are processed by a dry granulation process to a granulate with a mean particle size of 2 mm or less.
摘要翻译: 本发明公开了一种由包含混合组分(a)和(b)和(c)或(d)或两者的粉末组合物制备造粒产物的方法与(a)由自由基聚合的C1 - 丙烯酸或甲基丙烯酸的C 4-酯和(甲基)丙烯酸烷基酯单体与烷基侧基中的叔氨基(b)基于(a)的5-25重量%的C12- C18-单羧酸 (c)基于(a)基于(a)的碳原子数为3〜10的二羧酸为0〜10重量%,(c)0〜10重量%,(d)0〜20重量% 的具有至少14的HLB的乳化剂,其中所述混合组分通过干法制粒法加工成平均粒径为2mm或更小的颗粒。
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公开(公告)号:US20160193182A1
公开(公告)日:2016-07-07
申请号:US14911491
申请日:2014-08-01
CPC分类号: A61K31/40 , A61K9/284 , A61K9/2846 , A61K9/2893 , A61K9/5026 , A61K9/5089
摘要: The invention refers to a coating composition which, calculated on dry weight, is comprising at least 20% by weight polyvinyl alcohol and 0.1 to 20% by weight, calculated on the weight of the polyvinyl alcohol, of a water-insoluble (meth)acrylate copolymer comprising quaternary ammonium groups, wherein the viscosity of an aqueous dispersion comprising that coating composition with 25% (w/w) solid content at 22° C. is 200 mPa·s or less.
摘要翻译: 本发明涉及一种涂料组合物,其以干重计算,包含至少20重量%的聚乙烯醇和0.1至20重量%,以聚乙烯醇的重量计,水不溶性(甲基)丙烯酸酯 包含季铵基的共聚物,其中包含在22℃下具有25%(w / w)固体含量的涂料组合物的水性分散体的粘度为200mPa·s或更低。
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3.
公开(公告)号:US20180140556A1
公开(公告)日:2018-05-24
申请号:US15578746
申请日:2016-05-23
申请人: Sanjay LANKE , Shraddha Sanjeev JOSHI , Ashish Sharadchandra GUHA , Sanjay LANKE , Vinay JAIN , Firouz ASGARZADEH , Mitulkumar PATEL
发明人: Shraddha JOSHI , Ashish GUHA , Sanjay LANKE , Vinay JAIN , Firouz ASGARZADEH , Mitulkumar M PATEL
IPC分类号: A61K9/50 , A61K31/138 , A61K31/167 , A23L33/10
CPC分类号: A61K9/5073 , A23L33/10 , A23V2002/00 , A61K9/1652 , A61K9/501 , A61K9/5026 , A61K9/5036 , A61K9/5047 , A61K9/5089 , A61K31/138 , A61K31/167
摘要: The invention refers to a pharmaceutical or nutraceutical composition comprising a core a) comprising an active ingredient and a water-insoluble polymer, a coating layer b) above the core a) comprising a salt of an alginic acid, and a coating layer c) above the coating layer b) comprising an anionic (meth)acrylate copolymer polymerized from a (meth)acrylate monomer mixture comprising 5-75% by weight in relation to the total weight of the (meth)acrylate monomer mixture of (meth)acrylate monomers with an anionic group, wherein the amount of the water-insoluble polymer in the core a) is 2 to 20% by weight in relation to the weight of the core a) and the amount of the salt of an alginic acid in the coating layer b) is 5 to 85% by weight in relation to the weight of the core a) and the amount of the anionic (meth)acrylate copolymer in the coating layer c) is 10 to 75% by weight in relation to the weight of the core a) and to the coating layer b).
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4.
公开(公告)号:US20170304211A1
公开(公告)日:2017-10-26
申请号:US15518429
申请日:2015-11-23
申请人: Shraddha JOSHI , Ashish GUHA , Vinay JAIN
发明人: Shraddha JOSHI , Ashish GUHA , Vinay JAIN
IPC分类号: A61K9/50 , A61K31/135 , A61K31/522 , A61K31/138
CPC分类号: A61K9/5026 , A61K9/1635 , A61K9/1652 , A61K9/2846 , A61K9/286 , A61K9/2886 , A61K9/5036 , A61K9/5073 , A61K9/5089 , A61K31/135 , A61K31/138 , A61K31/522
摘要: A pharmaceutical or nutraceutical composition, contains a) a core a), containing a pharmaceutical or a nutraceutical active ingredient and b) a coating layer b), containing a mixture of 80 to 96% by weight of a water-insoluble (meth)acrylate polymer and 4 to 20% by weight of guar gum, wherein the water-insoluble (meth)acrylate polymer contains polymerized units of more than 95 and up to 100% by weight C1-C4-alkyl esters of acrylic acid or of methacrylic acid and less than 5% by weight of acrylic acid or methacrylic acid.
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