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1.Autonomously replicating plasmid and saccharomycopsis lipolytica transformed therewith 失效
标题翻译: 自动更换血浆和脂肪肝脂蛋白公开(公告)号:US5118625A
公开(公告)日:1992-06-02
申请号:US285032
申请日:1988-12-16
申请人: Shuichi Aiba , Tomohisa Nagasaki , Kohji Uchida
发明人: Shuichi Aiba , Tomohisa Nagasaki , Kohji Uchida
CPC分类号: C12N15/815 , C12N15/68 , Y10S435/911
摘要: The plasmid of the present invention contains Leu 2 gene (.beta.-isopropylmaleate dehydrogenase gene) from Saccharomycopsis lipolytica and an autonomously replicating sequence (hereafter referred to as ARS) and can be a shuttle vector between Escherichia coli and Saccharomycopsis lipolytica since it is produced from shuttle vector pVC 1 of Escherichia coli and Saccharomyces cerevisiae. An exogenous useful gene is inserted into the plasmid of the present invention, namely, shuttle vector to transform Escherichia coli, whereby a large quantity of plasmids are obtained. It becomes possible to produce a useful substance in Saccharomycopsis lipolytica as a host using the plasmid.
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公开(公告)号:US5616558A
公开(公告)日:1997-04-01
申请号:US83501
申请日:1993-06-30
申请人: Akira Ohneda , Kazuyuki Sasaki , Yohei Natori , Tomohisa Nagasaki
发明人: Akira Ohneda , Kazuyuki Sasaki , Yohei Natori , Tomohisa Nagasaki
IPC分类号: A61K38/00 , A61K38/26 , C07K14/605 , C07K14/00
CPC分类号: C07K14/605 , A61K38/26
摘要: Agents for stimulating insulin secretion and for treating diabetes which comprise glicentin as an active ingredient.
摘要翻译: 用于刺激胰岛素分泌和用于治疗糖尿病的药物,其包含作为活性成分的格列汀。
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3.
公开(公告)号:US5547938A
公开(公告)日:1996-08-20
申请号:US377833
申请日:1995-01-25
申请人: Seiki Matsuno , Iwao Sasaki , Akira Ohneda , Kazuyuki Sasaki , Yohei Natori , Tomohisa Nagasaki
发明人: Seiki Matsuno , Iwao Sasaki , Akira Ohneda , Kazuyuki Sasaki , Yohei Natori , Tomohisa Nagasaki
IPC分类号: A61K31/00 , A61K38/22 , A61K38/26 , A61P1/00 , A61P1/04 , A61P1/14 , A61P43/00 , C07K14/00 , C07K14/575 , C07K14/605
CPC分类号: A61K38/26
摘要: Therapeutic agents for the digestive tract diseases which comprise glicentin as active ingredients.
摘要翻译: 消化道疾病的治疗剂,其包含胃肠素作为活性成分。
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公开(公告)号:US5700776A
公开(公告)日:1997-12-23
申请号:US415939
申请日:1995-04-03
申请人: Akira Ohneda , Kazuyuki Sasaki , Yohei Natori , Tomohisa Nagasaki
发明人: Akira Ohneda , Kazuyuki Sasaki , Yohei Natori , Tomohisa Nagasaki
IPC分类号: A61K38/00 , A61K38/26 , C07K14/605 , C07K7/34
CPC分类号: C07K14/605 , A61K38/26
摘要: Agents for stimulating insulin secretion and for treating diabetes which comprise glicentin as an active ingredient.
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公开(公告)号:US5432156A
公开(公告)日:1995-07-11
申请号:US193863
申请日:1994-02-09
申请人: Seiki Matsuno , Iwao Sasaki , Akira Ohneda , Kazuyuki Sasaki , Yohei Natori , Tomohisa Nagasaki
发明人: Seiki Matsuno , Iwao Sasaki , Akira Ohneda , Kazuyuki Sasaki , Yohei Natori , Tomohisa Nagasaki
IPC分类号: A61K31/00 , A61K38/22 , A61K38/26 , A61P1/00 , A61P1/04 , A61P1/14 , A61P43/00 , C07K14/00 , C07K14/575 , C07K14/605
CPC分类号: A61K38/26
摘要: Therapeutic agents for the digestive tract diseases which comprise glicentin as active ingredients.
摘要翻译: 消化道疾病的治疗剂,其包含胃肠素作为活性成分。
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