公开(公告)号：US5468887A

公开(公告)日：1995-11-21

申请号：US851463

申请日：1992-03-13

Applicant: Shyam K. Gupta

Inventor： Shyam K. Gupta

IPC: C07C51/41 ,  C07C67/03 ,  C07C51/00

CPC classification number: C07C51/412 ,  C07C67/03

Abstract: A method of preparing esters and water soluble soaps using intensive mixing. The esters are prepared by reacting fats & oils with methanol containing caustic as a catalyst wherein the glycerin formed is removed. The resulting esters are saponified with caustic along with an additional amount of methanol to form the soap.

Abstract translation: 一种使用强烈混合制备酯和水溶性肥皂的方法。 通过使油脂与含有苛性碱的甲醇作为催化剂反应制备酯，其中除去形成的甘油。 所得的酯用苛性碱和附加量的甲醇皂化以形成皂。

公开(公告)号：US07438897B2

公开(公告)日：2008-10-21

申请号：US10249012

申请日：2003-03-10

Applicant: Shyam K. Gupta

Inventor： Shyam K. Gupta

IPC: A61K8/00

CPC classification number: A61K8/922 ,  A61K8/02 ,  A61K8/26 ,  A61K8/8111 ,  A61K2800/262 ,  A61Q9/04

Abstract: The present invention discloses cosmetic transparent hair removal (depilatory) compositions that: (1) Are transparent in appearance, (2) Can be made in cold wax or hot wax forms, (3) Manufactured at much less than 80 ° C., (4) Three-dimensional particles of visually attractive compositions can be added, (5) Bind more strongly with hair and less strongly with skin, (6) Can be applied either directly on the skin or applied on a piece of fabric, plastic, or paper first, which is then applied to skin for hair removal, and (7) Require minimal clean-up.

Abstract translation: 本发明公开了一种化妆品透明脱毛（脱毛剂）组合物，其特征在于：（1）外观透明，（2）可以以冷蜡或热蜡形式制成，（3）在远低于80℃，（ 4）可以添加视觉吸引人的组合物的三维颗粒，（5）与头发更强烈地绑着，并且与皮肤不太牢固;（6）可以直接涂在皮肤上或涂在一块织物，塑料或 纸首先用于皮肤脱毛，（7）需要最少的清理。

公开(公告)号：US20110077193A1

公开(公告)日：2011-03-31

申请号：US12957598

申请日：2010-12-01

Applicant: Shyam K. Gupta

Inventor： Shyam K. Gupta

IPC: A61K38/02 ,  C07D493/16 ,  C07K2/00 ,  C07H5/06 ,  C07D491/153 ,  A61K31/357 ,  A61K31/7008 ,  A61P33/00 ,  A61P35/00 ,  A61P3/10 ,  A61P17/06 ,  A61P17/04 ,  A61P29/00 ,  A61P17/00 ,  A61P17/10 ,  A61P17/12 ,  A61Q19/08 ,  A61Q19/00 ,  A61P31/04 ,  A61P31/10 ,  A61P33/02

CPC classification number: A61Q19/02 ,  A61K8/49 ,  A61K8/498 ,  A61K31/205 ,  A61K31/357 ,  A61K31/60 ,  A61K31/7008 ,  A61K31/728 ,  A61K2800/28 ,  A61Q5/006 ,  A61Q19/008 ,  A61K2300/00

Abstract: The present invention discloses certain derivatives of artemisinin and the active principles contained in Artemisia annua extracts with amino acids, peptides, and amino sugars, and isomers and salts thereof (formula I). The compounds of the present invention possess wide-spectrum antibacterial and antifungal biological activity suitable for topical or oral application for the treatment of infections and topical ailments in mammals, including acne, rosacea, topical wounds, infections, dandruff, skin disfigurements caused by infection, skin discoloration, age spots, wrinkles, excess facial oil, and veterinary problems including canine infections;

Abstract translation: 本发明公开了青蒿素的某些衍生物和含有氨基酸，肽和氨基糖的艾蒿提取物及其异构体和盐（式I）中的活性成分。 本发明的化合物具有广泛的抗菌和抗真菌生物活性，适用于局部或口服施用以治疗哺乳动物感染和局部疾病，包括痤疮，酒渣鼻，局部创伤，感染，头皮屑，由感染引起的皮肤损伤， 皮肤变色，老年斑，皱纹，多余面部油脂和兽医问题，包括犬类感染;

公开(公告)号：US20120264696A1

公开(公告)日：2012-10-18

申请号：US13400047

申请日：2012-02-18

Applicant: Shyam K. Gupta ,  Linda Walker

Inventor： Shyam K. Gupta ,  Linda Walker

IPC: A61K38/05 ,  C07K5/072 ,  A61P17/00 ,  C07K5/087 ,  C07K5/117 ,  A61K38/06 ,  C07K5/113 ,  A61K38/07

CPC classification number: A61K8/347 ,  A61K8/35 ,  A61K8/355 ,  A61K8/498 ,  A61K8/55 ,  A61K8/602 ,  A61Q19/02

Abstract: Preventing skin aging by targeting multiple causes by a single bullet is of primal scientific and consumer interest. A treatment based on compositions of compound (I) for cellular senescence to control cellular degradation offers such a solution to multiple skin ailments including skin degradation from cancer, diabetes, radiation treatments, chemotherapy, and sun-burn; mitochondrial dysfunction, age spots, acne, loss of cellular antioxidants, collagen loss, loss of skin pliability, loss of skin suppleness, skin wrinkles including fine lines, oxidation, damage from radiation, damage from free radicals, damage from UV, dry skin, xerosis, ichthyosis, dandruff, brownish spots, keratoses, melasma, lentigines, liver spots, pigmented spots, dark circles under the eyes, skin pigmentation including darkened skin, blemishes, oily skin, warts, eczema, pruritic skin, psoriasis, inflammatory dermatoses, topical inflammation, disturbed keratinization, skin changes associated with aging, scalp dryness, skin depigmentation, intracellular dehydration, and combinations thereof;

Abstract translation: 通过单个子弹针对多种原因预防皮肤老化是原始的科学和消费者的兴趣。 基于用于细胞衰老以控制细胞降解的化合物（I）的组合的治疗提供了对多种皮肤疾病（包括癌症，糖尿病，放射治疗，化学疗法和日光烧伤的皮肤降解）的解决方案。 线粒体功能障碍，老年斑，痤疮，细胞抗氧化剂丧失，胶原损失，皮肤柔韧性丧失，皮肤柔软度丧失，皮肤皱纹，包括细纹，氧化，辐射损伤，自由基损伤，紫外线，干性皮肤损伤， 皮肤色素沉着，包括变黑的皮肤，瑕疵，油性皮肤，疣，湿疹，瘙痒皮肤，牛皮癣，炎性皮肤病，皮肤瘙痒症，皮肤瘙痒症， 局部炎症，受干扰的角质化，与衰老相关的皮肤变化，头皮干燥，皮肤色素沉淀，细胞内脱水及其组合;

公开(公告)号：US4704223A

公开(公告)日：1987-11-03

申请号：US894445

申请日：1986-08-01

Applicant: Shyam K. Gupta ,  Julian R. Story

Inventor： Shyam K. Gupta ,  Julian R. Story

IPC: C11D9/00 ,  C11D9/26 ,  C11D9/48 ,  C11D17/00

CPC classification number: C11D9/48 ,  C11D9/007 ,  C11D9/267

Abstract: Toilet soap bars superfatted with branched chain fatty acids having from about 8 to 12 carbon atoms and where the branching occurs at the carbon position alpha to the carboxyl group.

Abstract translation: 用具有约8至12个碳原子的支链脂肪酸填充的卫生皂条，其中支链发生在羧基的α位置。

公开(公告)号：US08410079B2

公开(公告)日：2013-04-02

申请号：US13226661

申请日：2011-09-07

Applicant: David Wayne Peter ,  John Dillon Stanek ,  Cheria L. Orozco ,  Shyam K. Gupta

Inventor： David Wayne Peter ,  John Dillon Stanek ,  Cheria L. Orozco ,  Shyam K. Gupta

IPC: A61K9/00 ,  A61K8/02 ,  A61K31/665 ,  A01N57/00

CPC classification number: A61K8/19 ,  A61K8/498 ,  A61K8/55 ,  A61K31/675 ,  A61K31/7056 ,  A61K31/7076 ,  A61K31/7135 ,  A61K31/715 ,  A61K45/06 ,  A61K48/00 ,  A61Q5/006 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/004 ,  A61Q19/008 ,  A61Q19/02 ,  A61Q19/04 ,  A61Q19/08 ,  A61K2300/00

Abstract: The present invention discloses certain chirally correct polyene cyclodextrin acetals and hemiacetals (formula I) that are effective in providing skin clarification, which is useful for the treatment of acne, and skin disfigurements and skin darkening resulting from acne; skin darkening from cancer, diabetes, radiation treatments, chemotherapy, and sun-burn; mitochondrial and DNA dysfunction; age spots; loss of cellular antioxidants; skin changes associated with aging including collagen loss, loss of skin pliability, loss of skin suppleness, skin wrinkles and fine lines, oxidation, damage from radiation, damage from free radicals, and damage from UV; dry skin; xerosis; ichthyosis; dandruff; brownish spots; keratoses; melasma; lentigines; liver spots; skin pigmentation including pigmented spots, dark circles under the eyes, darkened skin, and blemishes; oily skin; warts; eczema; pruritic skin; psoriasis; inflammatory dermatoses; topical inflammation; disturbed keratinization; scalp dryness, and combinations thereof;

公开(公告)号：US20090130154A1

公开(公告)日：2009-05-21

申请号：US12361615

申请日：2009-01-29

Applicant: Shyam K. Gupta

Inventor： Shyam K. Gupta

IPC: A61K8/02 ,  A61Q19/02 ,  A61Q19/08 ,  A61Q19/00 ,  A61Q5/00 ,  A61Q15/00

CPC classification number: A61K8/19 ,  A61K8/0212 ,  A61K8/26 ,  A61K31/7135 ,  A61K31/715 ,  A61K38/063 ,  A61K45/06 ,  A61K48/00 ,  A61K2800/242 ,  A61Q5/02 ,  A61Q5/065 ,  A61Q11/00 ,  A61Q13/00 ,  A61Q15/00 ,  A61Q19/02 ,  A61Q19/08 ,  A61K2300/00

Abstract: The present invention discloses certain di- and polyvalent metal zeolite compounds (formula I) for topical delivery of biological and skin and hair care agents. The method of treating skin and hair condition via topical application of said zeolite compounds is also disclosed. The said method provides a treatment for topical condition, which includes alleviation of skin conditions such as skin rash including diaper rash, dry skin, scalp dandruff, broken or chafed skin, sunburn, skin damage from UV, skin irritation, acne including excess facial oil and facial pore size; darkened skin including age spots, dark circles around the eyes, and discoloration of skin from stretch marks; skin aging including wrinkles and fine lines; loss of collagen including thinning skin and loss of skin pliability; body odor, including oral cavity odor, arm-pit odor, and incontinence odor; cellular inflammation including intracellular and extra cellular inflammation; premature hair aging including premature hair loss hair graying; malfunction of tyrosinase group of enzymes, malfunction of matrix metalloprotease group of enzymes; and combinations thereof. The said method also provides topical delivery of certain metals, including trace metals, and certain zirconium aluminum amino acids that provide antiperspirant benefits;

Abstract translation: 本发明公开了用于局部递送生物和皮肤和护发剂的某些二价和多价金属沸石化合物（式I）。 还公开了通过局部施用所述沸石化合物治疗皮肤和毛发状况的方法。 所述方法提供了局部病症的治疗，其包括减轻皮肤病症如皮疹，例如皮疹，包括尿布疹，干性皮肤，头皮头皮屑，破裂或擦伤的皮肤，晒伤，紫外线皮肤损伤，皮肤刺激，痤疮，包括过量面部油 和面孔孔径; 皮肤变黑，包括老年斑，眼睛周围的黑眼圈，以及妊娠纹皮肤变色; 皮肤老化包括皱纹和细纹; 胶原蛋白损失包括皮肤变薄和皮肤柔韧性丧失; 身体异味，包括口腔气味，手臂坑气味和失禁气味; 细胞炎症包括细胞内和细胞外炎症; 头发老化过早，包括头发脱发过早脱发; 酪氨酸酶组酶失活，酶基质金属蛋白酶组失常; 及其组合。 所述方法还提供某些金属（包括痕量金属）和提供止汗益处的某些锆铝氨基酸的局部递送;

公开(公告)号：US3965191A

公开(公告)日：1976-06-22

申请号：US560304

申请日：1975-03-20

Applicant: Shyam K. Gupta

Inventor： Shyam K. Gupta

IPC: C07C47/127 ,  C07C45/00

CPC classification number: C07C45/71

Abstract: A one-step process for the synthesis of methyl glyoxal acetals from dihydroxyacetone wherein dihydroxyacetone, an alkanol and an acid catalyst are reacted to produce the acetals.

Abstract translation: 将二羟基丙酮，链烷醇和酸催化剂与二羟基丙酮合成甲基乙二醛缩醛的一步法反应生成缩醛。