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公开(公告)号：US20210365667A1
公开(公告)日：2021-11-25
申请号：US16980835
申请日：2019-03-11
发明人： Lukas RICHTER , Oliver HAYDEN , Matthias UGELE , Markus WENIGER , Oliver SCHMIDT , Manfred STANZEL
摘要： The invention relates to an in-vitro method for determining a cell type of a white blood cell in a biological sample without labeling, wherein a microscopy apparatus images the cell and physical parameters of the cell are ascertained from the image of the cell by means of an automated image analysis, wherein the cell type of the white blood cell is determined on the basis of the physical parameters and on the basis of principal component analysis parameters (PCA parameters), wherein the principal component analysis parameters comprise linear combinations of at least some of the physical parameters.
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公开(公告)号：US20180232882A1
公开(公告)日：2018-08-16
申请号：US15750990
申请日：2016-09-22
发明人： Saikiran RAPAKA , Ali KAMEN , Noha EL-ZEHIRY , Bogdan GEORGESCU , Anton SCHICK , Uwe PHILIPPI , Oliver HAYDEN , Lukas RICHTER , Matthias UGELE
IPC分类号： G06T7/00 , G06T7/11 , G06K9/62 , G06T5/00 , G06T7/55 , G06K9/00 , G03H1/00 , G03H1/04 , G03H1/16 , G03H1/08 , G01N15/14
CPC分类号： G06T7/0014 , G01N15/1429 , G01N15/1434 , G01N15/1475 , G01N2015/1006 , G01N2015/1454 , G03H1/0005 , G03H1/0443 , G03H1/0866 , G03H1/16 , G03H2001/005 , G03H2001/0452 , G03H2001/0883 , G03H2210/55 , G06K9/0014 , G06K9/6255 , G06K2209/403 , G06T5/005 , G06T7/11 , G06T7/55 , G06T2207/10056 , G06T2207/20081 , G06T2207/30024
摘要： A computer-implemented method for analyzing digital holographic microscopy (DHM) data for hematology applications includes receiving a DHM image acquired using a digital holographic microscopy system. The DHM image comprises depictions of one or more cell objects and background. A reference image is generated based on the DHM image. This reference image may then be used to reconstruct a fringe pattern in the DHM image into an optical depth map.
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