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1.发明授权公开(公告)号：US11946850B2
公开(公告)日：2024-04-02
申请号：US17127980
申请日：2020-12-18
Applicant: IMEC VZW
Inventor： Geert Vanmeerbeeck , Ziduo Lin , Abdulkadir Yurt , Richard Stahl , Andy Lambrechts
IPC: G01N15/14 , G01N15/1434 , G03H1/08 , G01N15/06
CPC classification number: G01N15/1434 , G03H1/0866 , G01N15/06 , G01N2015/1454 , G01N2015/1486 , G03H2001/0883
Abstract: A device for detecting particles in air; said device comprising:
a receiver for receiving a flow of air comprising particles;
a particle capturing arrangement configured to transfer the particles from the flow of air to a liquid for collection of a set of particles in the liquid;
a flow channel configured to pass a flow of the liquid comprising the set of particles through the flow channel;
a light source configured to illuminate the set of particles in the flow channel, such that an interference pattern is formed by interference between light being scattered by the set of particles and non-scattered light from the light source; and
an image sensor comprising a plurality of photo-sensitive elements configured to detect incident light, the image sensor being configured to detect the interference pattern.-
公开(公告)号：US20180150027A1
公开(公告)日：2018-05-31
申请号：US15819656
申请日：2017-11-21
Inventor： Yongkyu KIM , Kichul KIM , Hojung KIM , Hongseok LEE
CPC classification number: G03H1/0005 , G03H1/0808 , G03H1/0866 , G03H1/16 , G03H2001/0088 , G03H2001/045 , G03H2001/0452 , G03H2001/0833 , G03H2001/0883 , G03H2210/454 , G03H2226/02
Abstract: A method of obtaining a focus term by using a periodicity of the focus term is provided. The focus term may be used in a plurality of operation processes for processing image data.
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公开(公告)号：US20170322516A1
公开(公告)日：2017-11-09
申请号：US15528202
申请日：2015-11-30
Applicant: IMEC TAIWAN CO. , IMEC VZW
Inventor： Ching-Chun Hsiao , Ting-Ting Chang , Chao-Kang Liao
CPC classification number: G03H1/0866 , G03H1/0443 , G03H2001/0447 , G03H2001/0883 , G06T7/11 , G06T7/13 , G06T7/136 , G06T7/187
Abstract: At least one embodiment relates to an autofocus method for determining a focal plane for at least one object. The method includes reconstructing a holographic image of the at least one object such as to provide a reconstructed image at a plurality of different focal depths. The reconstructed image includes a real component and an imaginary component. The method also include performing a first edge detection on the real component for at least two depths of the plurality of different focal depths and a second edge detection on the imaginary component for the at least two depths. Further, the method includes obtaining a first measure of clarity for each of the at least two depths based on a first measure of statistical dispersion with respect to the first edge detection and a second measure of clarity.
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公开(公告)号：US20170309036A1
公开(公告)日：2017-10-26
申请号：US15526092
申请日：2015-11-13
Inventor： Francois PERRAUT , Pierre JOLY , Quentin JOSSO , Meike KLOSTER-LANDSBERG
CPC classification number: G06T7/55 , G01N15/1434 , G01N15/1463 , G01N15/1475 , G01N21/453 , G01N21/4788 , G01N2015/0065 , G01N2015/1006 , G01N2015/1445 , G01N2015/1452 , G01N2015/1454 , G03H1/0005 , G03H1/041 , G03H1/0443 , G03H1/0866 , G03H2001/0033 , G03H2001/005 , G03H2001/0428 , G03H2001/0447 , G03H2001/0452 , G03H2001/0467 , G03H2001/0883 , G06T7/97 , G06T15/10
Abstract: A method of analyzing a sample receiving a particle of interest, including: defining a reference point located on a first interface of the sample, or at a known distance from the sample, along the optical axis of the optical system; acquiring a reference image transmission of the sample, the object plane of the optical system being located at a known distance from the reference point along an axis parallel to the optical axis of the optical system, and the particle of interest being located outside of the object plane; using the reference image, digitally constructing a series of reconstructed images, each associated with a predetermined offset of the object plane along the optical axis of the optical system; and using the series of reconstructed images, determining the distance along an axis parallel to the optical axis of the optical system, between the particle of interest and the reference point.
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公开(公告)号：US20150153558A1
公开(公告)日：2015-06-04
申请号：US14406199
申请日：2013-06-05
Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor： Aydogan Ozcan , Onur Mudanyali , Euan McLeod
CPC classification number: G02B21/367 , G01B9/04 , G01N15/1434 , G01N15/1463 , G01N2015/1006 , G01N2015/144 , G02B3/12 , G02B21/0004 , G02B21/14 , G02B21/34 , G03H1/0443 , G03H1/0465 , G03H1/0866 , G03H2001/0447 , G03H2001/0883 , G03H2222/36 , G03H2240/56
Abstract: A method of imaging a sample includes depositing a droplet containing the sample on a substrate, the sample having a plurality of particles contained within a fluid. The substrate is then tilted to gravitationally drive the droplet to an edge of the substrate while forming a dispersed monolayer of particles having liquid lenses surrounding the particles. A plurality of lower resolution images of the particles contained on the substrate are obtained, wherein the substrate is interposed between an illumination source and an image sensor, wherein each lower resolution image is obtained at discrete spatial locations. The plurality of lower resolution images of the particles are converted into a higher resolution image. At least one of an amplitude image and a phase image of the particles contained within the sample is then reconstructed. In some embodiments, only a single lower resolution image may be sufficient.
Abstract translation: 成像样品的方法包括将含有样品的液滴沉积在基底上，样品具有包含在流体内的多个颗粒。 然后将衬底倾斜以重力地将液滴驱动到衬底的边缘，同时形成具有围绕颗粒的液体透镜的分散的单层颗粒。 获得包含在基板上的颗粒的多个较低分辨率图像，其中基板被插入在照明源和图像传感器之间，其中在离散的空间位置处获得每个下分辨率图像。 颗粒的多个较低分辨率图像被转换成更高分辨率的图像。 然后重建样品中包含的颗粒的幅度图像和相位图像中的至少一个。 在一些实施例中，仅一个较低分辨率的图像可能是足够的。
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Patent Agency Ranking
6.发明申请公开(公告)号：US20140218684A1
公开(公告)日：2014-08-07
申请号：US14164955
申请日：2014-01-27
Applicant: Carl Zeiss Meditec, Inc.
Inventor： Abhishek KUMAR , Alexandre R. TUMLINSON , Rainer LEITGEB
IPC: A61B3/10
CPC classification number: A61B3/102 , A61B3/0025 , A61B3/14 , G01N21/4795 , G01N2021/1787 , G03H1/041 , G03H1/0866 , G03H2001/005 , G03H2001/0083 , G03H2001/0452 , G03H2001/0883 , G03H2210/30 , G03H2222/14 , G03H2222/23 , G03H2223/52 , G03H2223/55
Abstract: Systems and methods for sub-aperture correlation based wavefront measurement in a thick sample and correction as a post processing technique for interferometric imaging to achieve near diffraction limited resolution are described. Theory, simulation and experimental results are presented for the case of full field interference microscopy. The inventive technique can be applied to any coherent interferometric imaging technique and does not require knowledge of any system parameters. In one embodiment of the present invention, a fast and simple way to correct for defocus aberration is described. A variety of applications for the inventive method are presented.
Abstract translation: 描述了厚样本中基于子孔径相关的波前测量的系统和方法以及用于干涉成像实现近衍射限制分辨率的后处理技术的校正。 介绍了全场干涉显微镜的理论，仿真和实验结果。 本发明的技术可以应用于任何相干干涉成像技术，并且不需要任何系统参数的知识。 在本发明的一个实施例中，描述了用于校正散焦像差的快速且简单的方法。 介绍了本发明方法的各种应用。
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公开(公告)号：US20190250560A1
公开(公告)日：2019-08-15
申请号：US16336890
申请日：2017-09-29
Applicant: Siemens Healthcare GmbH
Inventor： Thomas ENGEL , Oliver HAYDEN
CPC classification number: G03H1/0005 , G03H1/0443 , G03H1/0866 , G03H1/265 , G03H2001/005 , G03H2001/0216 , G03H2001/0445 , G03H2001/0452 , G03H2001/0456 , G03H2001/0875 , G03H2001/0883 , G03H2001/267 , G03H2222/45 , G03H2223/20 , G03H2223/22 , G03H2227/03
Abstract: The invention relates to a device, such as a digital holographic microscope (1), for detecting and processing a first full image of a measurement object, measured with a first offset, wherein an arrangement is provided for generating at least one further full image with at least one offset that differs from said first offset.
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8.发明授权公开(公告)号：US10078305B2
公开(公告)日：2018-09-18
申请号：US15294314
申请日：2016-10-14
Applicant: UChicago Argonne, LLC
Inventor： Andrew P. Ulvestad , Stephan O. Hruszkewycz , Paul H. Fuoss , Stefan M. Wild , Ashish Tripathi
CPC classification number: G03H1/0866 , G01N21/4788 , G01N23/04 , G01N23/207 , G01N2021/1785 , G01N2223/401 , G03H1/0402 , G03H1/0443 , G03H2001/0428 , G03H2001/0441 , G03H2001/0454 , G03H2001/0875 , G03H2001/0883 , G03H2001/2655 , G03H2210/30 , G03H2210/62
Abstract: A method for retrieving phase information in a coherent diffraction imaging process includes acquiring a plurality of 3D data sets, each 3D data set corresponding to one of a plurality of time states, and reconstructing a 3D image of the object at a given time state using the 3D data set from all of the time states. Each 3D data set is acquired by: illuminating an object positioned in a first position with a coherent beam; measuring a first 2D diffraction pattern using an area detector; rotating the object around a tilt axis thereof to a second position that is different from the first position; re-illuminating the object positioned in the second position with the coherent beam; re-measuring a second 2D diffraction pattern using the area detector; and repeating the rotating, re-illuminating and re-measuring steps such that each 3D data set includes a predetermined number of diffraction patterns.
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公开(公告)号：US20180232882A1
公开(公告)日：2018-08-16
申请号：US15750990
申请日：2016-09-22
Applicant: Siemens Healthcare GmbH
Inventor： Saikiran RAPAKA , Ali KAMEN , Noha EL-ZEHIRY , Bogdan GEORGESCU , Anton SCHICK , Uwe PHILIPPI , Oliver HAYDEN , Lukas RICHTER , Matthias UGELE
IPC: G06T7/00 , G06T7/11 , G06K9/62 , G06T5/00 , G06T7/55 , G06K9/00 , G03H1/00 , G03H1/04 , G03H1/16 , G03H1/08 , G01N15/14
CPC classification number: G06T7/0014 , G01N15/1429 , G01N15/1434 , G01N15/1475 , G01N2015/1006 , G01N2015/1454 , G03H1/0005 , G03H1/0443 , G03H1/0866 , G03H1/16 , G03H2001/005 , G03H2001/0452 , G03H2001/0883 , G03H2210/55 , G06K9/0014 , G06K9/6255 , G06K2209/403 , G06T5/005 , G06T7/11 , G06T7/55 , G06T2207/10056 , G06T2207/20081 , G06T2207/30024
Abstract: A computer-implemented method for analyzing digital holographic microscopy (DHM) data for hematology applications includes receiving a DHM image acquired using a digital holographic microscopy system. The DHM image comprises depictions of one or more cell objects and background. A reference image is generated based on the DHM image. This reference image may then be used to reconstruct a fringe pattern in the DHM image into an optical depth map.
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公开(公告)号：US20180188687A1
公开(公告)日：2018-07-05
申请号：US15453174
申请日：2017-03-08
Applicant: Microsoft Technology Licensing, LLC
Inventor： Andrew Maimone , Andreas Georgiou , Joel Steven Kollin
CPC classification number: G03H1/0891 , G02B5/32 , G02B27/0093 , G02B27/017 , G02B27/0172 , G02B2027/011 , G02B2027/014 , G02B2027/0174 , G02B2027/0178 , G03H1/0486 , G03H1/0808 , G03H1/0866 , G03H1/2205 , G03H1/2286 , G03H1/2294 , G03H2001/0491 , G03H2001/0883 , G03H2001/2284 , G03H2001/264 , G03H2210/44 , G03H2222/52 , G03H2223/23 , G03H2225/55 , G03H2226/02
Abstract: Examples are disclosed that relate to holographic near-eye display systems. One example provides a near-eye display device, comprising a diverging light source, an image producing dynamic digital hologram panel configured to receive light from the diverging light source and form an image. The near-eye display device also includes and a combiner comprising a holographic optical element positioned to receive light from the dynamic digital hologram panel and to redirect the light toward an eyebox, the holographic optical element being positioned between the eyebox and a view of an external environment to combine a view of the image formed by the dynamic digital hologram panel and the view of the external environment.
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