摘要:
Disclosed are compounds, compositions and methods for the prevention and/or treatment of diseases which are pathophysiologically mediated by the ghrelin receptor. The compounds have the general formula (I):
摘要:
Disclosed are compounds, compositions and methods for the prevention and/or treatment of diseases which are pathophysiologically mediated by the ghrelin receptor. The compounds have the general formula (I):
摘要:
Disclosed are compounds, compositions and methods for the prevention and/or treatment of diseases which are pathophysiologically mediated by the neurokinin (NK1) receptor. The compounds have the general formula (I):
摘要:
Disclosed are compounds, compositions and methods for the prevention and/or treatment of diseases which are pathophysiologically mediated by the neurokinin (NK1) receptor. The compounds have the general formula (I):
摘要:
Disclosed are compounds, compositions and methods for the prevention and/or treatment of diseases which are pathophysiologically mediated by the neurokinin (NK1) receptor. The compounds have the general formula (I):
摘要:
The invention relates to an ORC (Organic Rankine Cycle) for the conversion of thermal energy into electric energy, comprising at least one heat exchanger unit for re-superheating the working fluid by means of the thermovector fluid from the hot source, between the discharge of the first expander and the input of the second expander, and a regenerator unit including a first regenerator and at least one second regenerator for regenerating the working fluid in at least two successive stages, in said first regenerator and at least in said second regenerator respectively, with an additional regenerative heat exchange along the flow line connecting the liquid working fluid output of the second regenerator to the liquid working fluid input of the first regenerator.
摘要:
The present invention relates to methods for reducing the frequency of bladder contractions without significantly affecting micturition pressure, comprising administering a pharmaceutical composition comprising a therapeutically effective amount of netupitant, or a pharmaceutically acceptable salt or prodrug thereof. The method can be used to treat bladder dysfunction without significantly increasing residual volume, including urgency, frequency, pollakiuria, nocturia, low deferment time, suboptimal volume threshold, neurogenic bladder, or combinations thereof.
摘要:
The present invention relates to the use of 2-indanylamino derivatives for the treatment of chronic pain. In particular the invention relates to the use of 2-(2-indanylamino)-acetamide for the treatment of neuropathic pain, i.e. the pain associated with postherpetic neuralgia, trigeminal neuralgia, diabetic neuropathy and nerve distruction by the human immunodeficiency virus (HIV).
摘要:
The invention relates to an ORC (Organic Rankine Cycle) for the conversion of thermal energy into electric energy, comprising at least one heat exchanger unit for re-superheating the working fluid by means of the thermovector fluid from the hot source, between the discharge of the first expander and the input of the second expander, and a regenerator unit including a first regenerator and at least one second regenerator for regenerating the working fluid in at least two successive stages, in said first regenerator and at least in said second regenerator respectively, with an additional regenerative heat exchange along the flow line connecting the liquid working fluid output of the second regenerator to the liquid working fluid input of the first regenerator.
摘要:
The present invention relates to serinamide, glycinamide, alaninamide and phenylalaninamide derivatives of formula (I) wherein R, R', R.sub.1 and R.sub.2 are as defined in the disclosure. The compounds (I) are useful for the treatment of neurological diseases. ##STR1##