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1.发明申请Wound dressings, apparatus, and methods for controlling severe, life-threatening bleeding 有权用于控制严重的危及生命的出血的伤口敷料，仪器和方法公开(公告)号：US20080064998A1
公开(公告)日：2008-03-13
申请号：US11981111
申请日：2007-10-31
Applicant: Kenton Gregory , Simon McCarthy
Inventor： Kenton Gregory , Simon McCarthy
CPC classification number: A61L15/425 , A61F13/00012 , A61F13/00034 , A61F13/00987 , A61F13/00995 , A61F13/15203 , A61F2013/00106 , A61F2013/00463 , A61F2013/00468 , A61F2013/00472 , A61F2013/00536 , A61F2013/0054 , A61F2013/00931 , A61L15/28 , A61L2400/04 , C08L5/08
Abstract: A chitosan biomaterial is frozen in aqueous solution to form a frozen chitosan structure from which water is removed by a prescribed freeze-drying process to form a sponge-like chitosan structure having a thickness and a density. The sponge-like chitosan structure is compressed by application of heat and pressure to reduce the thickness and increase the density of the sponge-like chitosan structure to form a densified chitosan structure. The densified chitosan structure is further preconditioned by heating the densified chitopsan structure according to prescribed conditions to form a wound dressing. The wound dressing possesses an adhesion strength and resistance to dissolution in high blood flow bleeding situations.
Abstract translation: 将壳聚糖生物材料在水溶液中冷冻以形成冷冻的壳聚糖结构，通过规定的冷冻干燥方法从其中除去水，形成具有厚度和密度的海绵状壳聚糖结构。 通过施加热和压力来压缩海绵状壳聚糖结构，以减小海绵状壳聚糖结构的厚度和增加密度，形成致密化的壳聚糖结构。 通过根据规定的条件加热致密的小丘组织来进一步预处理致密的壳聚糖结构，以形成伤口敷料。 伤口敷料在高血流量出血的情况下具有粘附强度和抗溶解性。
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2.发明申请Supple tissue dressing assemblies, systems, and methods formed from hydrophilic polymer sponge structures such as chitosan 审中-公开由亲水聚合物海绵结构如壳聚糖形成的柔软组织敷料组件，系统和方法公开(公告)号：US20070066920A1
公开(公告)日：2007-03-22
申请号：US11520230
申请日：2006-09-13
Applicant: Lance Hopman , Clinton Pepper , Michael Radovan , Simon McCarthy
Inventor： Lance Hopman , Clinton Pepper , Michael Radovan , Simon McCarthy
CPC classification number: A61F13/00995 , A61F13/00034 , A61F13/00038 , A61F2013/00157 , A61F2013/00463 , A61F2013/00472 , A61F2013/00519 , A61F2013/0054 , A61F2013/00931 , A61L15/28 , A61L15/425 , A61L2400/04 , C08L5/08
Abstract: Supple tissue dressing assemblies are formed from hydrophilic polymer sponge structures, such as chitosan. The supple tissue dressing assemblies are characterized by suppleness or multi-dimensional flexibility. The assemblies can be flexed, bent, folded, twisted, and even rolled upon itself before and during use, without creasing, cracking, fracturing, otherwise compromising the integrity and mechanical and/or therapeutic characteristics of the assemblies.
Abstract translation: 柔软的组织敷料组件由亲水聚合物海绵结构如壳聚糖形成。 柔软的组织敷料组件的特征在于柔软性或多维度的柔韧性。 组件可以在使用之前和使用期间弯曲，弯曲，折叠，扭曲，甚至卷起，而不会起皱，开裂，断裂，否则会损害组件的完整性和机械和/或治疗特性。
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3.发明授权Wound dressings, apparatus, and methods for controlling severe, life-threatening bleeding 有权用于控制严重的危及生命的出血的伤口敷料，仪器和方法公开(公告)号：US07820872B2
公开(公告)日：2010-10-26
申请号：US11981111
申请日：2007-10-31
Applicant: Kenton W Gregory , Simon McCarthy
Inventor： Kenton W Gregory , Simon McCarthy
IPC: A61F13/00
CPC classification number: A61L15/425 , A61F13/00012 , A61F13/00034 , A61F13/00987 , A61F13/00995 , A61F13/15203 , A61F2013/00106 , A61F2013/00463 , A61F2013/00468 , A61F2013/00472 , A61F2013/00536 , A61F2013/0054 , A61F2013/00931 , A61L15/28 , A61L2400/04 , C08L5/08
Abstract: A chitosan biomaterial is frozen in aqueous solution to form a frozen chitosan structure from which water is removed by a prescribed freeze-drying process to form a sponge-like chitosan structure having a thickness and a density. The sponge-like chitosan structure is compressed by application of heat and pressure to reduce the thickness and increase the density of the sponge-like chitosan structure to form a densified chitosan structure. The densified chitosan structure is further preconditioned by heating the densified chitosan structure according to prescribed conditions to form a wound dressing. The wound dressing possesses an adhesion strength and resistance to dissolution in high blood flow bleeding situations.
Abstract translation: 将壳聚糖生物材料在水溶液中冷冻以形成冷冻的壳聚糖结构，通过规定的冷冻干燥方法从其中除去水，形成具有厚度和密度的海绵状壳聚糖结构。 通过施加热和压力来压缩海绵状壳聚糖结构，以减小海绵状壳聚糖结构的厚度和增加密度，形成致密化的壳聚糖结构。 通过根据规定的条件加热致密的壳聚糖结构，进一步预处理致密壳聚糖结构，形成伤口敷料。 伤口敷料在高血流量出血的情况下具有粘附强度和抗溶解性。
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公开(公告)号：US20070083137A1
公开(公告)日：2007-04-12
申请号：US11541988
申请日：2006-10-02
Applicant: Lance Hopman , Clinton Pepper , Dragos Mihalache , Michael Radovan , Simon McCarthy
Inventor： Lance Hopman , Clinton Pepper , Dragos Mihalache , Michael Radovan , Simon McCarthy
IPC: A61F13/00
CPC classification number: A61F13/00995 , A61F13/00034 , A61F13/00038 , A61F2013/00157 , A61F2013/00463 , A61F2013/00472 , A61F2013/00519 , A61F2013/00931 , A61L15/28 , A61L15/425 , C08L5/08
Abstract: Supple tissue dressing assemblies are formed from hydrophilic polymer sponge structures, such as chitosan. The supple tissue dressing assemblies are characterized by suppleness or multi-dimensional flexibility. The assemblies can be flexed, bent, folded, twisted, and even rolled upon itself before and during use, without creasing, cracking, fracturing, otherwise compromising the integrity and mechanical and/or therapeutic characteristics of the assemblies.
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5.发明申请Hemostatic compositions, assemblies, systems, and methods employing particulate hemostatic agents formed from hydrophilic polymer foam such as chitosan 有权使用由亲水聚合物泡沫如壳聚糖形成的颗粒止血剂的止血组合物，组件，系统和方法公开(公告)号：US20070021703A1
公开(公告)日：2007-01-25
申请号：US11485886
申请日：2006-07-13
Applicant: Simon McCarthy
Inventor： Simon McCarthy
IPC: A61F13/00
CPC classification number: A61L26/0023 , A61L15/28 , A61L26/0061 , A61L2400/04 , Y10T428/2982 , C08L5/08
Abstract: Improved hemostatic agents take the form of granules or particles that can be used to stanch, seal, or stabilize a site of hemorrhage, including a noncompressible hemorrhage.
Abstract translation: 改善的止血剂采取颗粒或颗粒的形式，其可用于窒息，密封或稳定出血部位，包括不可压缩的出血。
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Patent Agency Ranking
6.发明申请Compositions, assemblies, and methods applied during or after a dental procedure to ameliorate fluid loss and/or promote healing, using a hydrophilic polymer sponge structure such as chistosan 有权在牙科手术期间或之后施用的组合物，组合物和方法，以使用亲水性聚合物海绵结构例如chistosan来改善流体损失和/或促进愈合公开(公告)号：US20060089584A1
公开(公告)日：2006-04-27
申请号：US11261351
申请日：2005-10-28
Applicant: Staci McAdams , William Block , Simon McCarthy , Kenton Gregory
Inventor： Staci McAdams , William Block , Simon McCarthy , Kenton Gregory
CPC classification number: A61L15/425 , A61F13/2008 , A61F13/2051 , A61F13/36 , A61F2013/00472 , A61F2013/0054 , A61F2013/00927 , A61L15/28 , A61L2400/04 , A61L2430/12 , C08L5/08
Abstract: Dental dressing assemblies are formed from hydrophilic polymer sponge structures, such as a densified chitosan biomaterial.
Abstract translation: 牙科修整组件由亲水聚合物海绵结构形成，例如致密的壳聚糖生物材料。
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公开(公告)号：US12114722B2
公开(公告)日：2024-10-15
申请号：US18048989
申请日：2022-10-24
Applicant: Simon McCarthy
Inventor： Simon McCarthy
IPC: A42B1/008
CPC classification number: A42B1/008
Abstract: A hat headliner with temperature control members that is configured to provide a temperature dissimilar to that of its environment at locations along a lower edge of a hat. The present invention includes a body that is either permanently or releasably secured into the head cavity of a hat. The body of the present invention includes a perimeter band member wherein the perimeter band member has formed therein a plurality of receptacles. The plurality of receptacles have an interior volume wherein the interior volume is configured to receive and store temperature members. The temperature members include a housing from a malleable material having a temperature controlling gel therein. The receptacles have a first side and a second side wherein the first side of the receptacle is manufactured from a thermally conductive material and is adjacent a wearer's head.
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公开(公告)号：US20110111012A1
公开(公告)日：2011-05-12
申请号：US12590712
申请日：2009-11-12
Applicant: Clinton B. Pepper , Simon McCarthy , Keith Real , Jess Kimball , Jana Ruzickova , Jana Svobodova , Lucia Silovska , Jitka Vankova , Jiri Machat , Radim Dvorak
Inventor： Clinton B. Pepper , Simon McCarthy , Keith Real , Jess Kimball , Jana Ruzickova , Jana Svobodova , Lucia Silovska , Jitka Vankova , Jiri Machat , Radim Dvorak
IPC: A61K9/70 , A61K33/38 , A61K38/16 , A61K31/715 , A61K31/722 , A61K31/717 , A61P19/02 , B32B37/02 , B29C47/00
CPC classification number: B32B38/0004 , A61F13/00995 , A61F2013/00463 , A61F2013/00931 , A61F2013/00936 , B32B37/00 , B32B2535/00 , Y10T156/10
Abstract: Wound dressing assemblies and methods of producing the wound dressing assemblies. The wound dressing assemblies various comprise individual layers of nanomaterials that have been formed according to an electrospinning process.Each of the layers can have different characteristics and qualities. The invention also provides guidance in selecting materials to form a wound dressing assembly, as well as possible adaptations to the electrospinning process to provide different characteristics for particular materials.
Abstract translation: 伤口敷料组件及其制造方法。 伤口敷料组件各种包括根据静电纺丝工艺形成的纳米材料的单独层。 每个层可以具有不同的特征和质量。 本发明还提供了选择材料以形成伤口敷料组件的指导，以及可能适应于静电纺丝过程以为特定材料提供不同特性。
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9.发明申请Absorbable tissue dressing assemblies, systems, and methods formed from a Hydrophilic chitosan sponge structure and including a flexible absorbable backing layer of poly-4-hydroxy butyrate 审中-公开可吸收的组织敷料组件，系统和由亲水壳聚糖海绵结构形成的方法，并且包括聚-4-羟基丁酸酯的柔性可吸收背衬层公开(公告)号：US20090024068A1
公开(公告)日：2009-01-22
申请号：US12218571
申请日：2008-07-16
Applicant: Simon McCarthy , Barbara McGrath , Ervelyn Winata
Inventor： Simon McCarthy , Barbara McGrath , Ervelyn Winata
IPC: A61F13/02
CPC classification number: A61F13/00995 , A61F13/00063 , A61F2013/00157 , A61F2013/00472 , A61F2013/00519 , A61F2013/00931 , A61L15/28 , A61L15/425 , A61L15/64 , C08L5/08
Abstract: Absorbable tissue dressing assemblies are formed from hydrophilic polymer sponge structures, such as chitosan.
Abstract translation: 可吸收组织敷料组件由亲水聚合物海绵结构如壳聚糖形成。
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10.发明申请Tissue dressing assemblies, systems, and methods formed from hydrophilic polymer sponge structures such as chitosan 审中-公开由亲水聚合物海绵结构如壳聚糖形成的组织敷料组件，系统和方法公开(公告)号：US20050147656A1
公开(公告)日：2005-07-07
申请号：US11020365
申请日：2004-12-23
Applicant: Simon McCarthy , Kenton Gregory , John Morgan
Inventor： Simon McCarthy , Kenton Gregory , John Morgan
CPC classification number: A61F13/00995 , A61F13/00034 , A61F2013/00157 , A61F2013/0028 , A61F2013/00463 , A61F2013/00472 , A61F2013/00519 , A61F2013/00536 , A61F2013/0054 , A61F2013/00544 , A61F2013/00931 , A61K31/722 , A61L15/28 , A61L15/425 , A61L33/08 , A61L2400/04 , C08L5/08
Abstract: Tissue dressing assemblies are formed from hydrophilic polymer sponge structures. The tissue dressing assemblies can be used, e.g., (i) stanch, seal, or stabilize a site of tissue injury, tissue trauma, or tissue access; or (ii) form an anti-microbial barrier; or (iii) form an antiviral patch; or (iv) intervene in a bleeding disorder; or (v) release a therapeutic agent; or (vi) treat a mucosal surface; or (vii) combinations thereof. The tissue dressing structures are made compliant, e.g., by (i) micro-fracturing of a substantial portion of the sponge structure by mechanical manipulation prior to use, or (ii) a surface relief pattern formed on a substantial portion of the sponge structure prior to use, or (iii) a pattern of fluid inlet channels formed in a substantial portion of the sponge structure prior to use, or (iv) the impregnation of a sheet material within the sponge structure.
Abstract translation: 组织敷料组件由亲水聚合物海绵结构形成。 可以使用组织敷料组件，例如（i）固定，密封或稳定组织损伤，组织创伤或组织进入部位; 或（ii）形成抗微生物屏障; 或（iii）形成抗病毒贴片; 或（iv）介入出血性疾病; 或（v）释放治疗剂; 或（vi）治疗粘膜表面; 或（vii）其组合。 组织修整结构被制成顺应性，例如通过（i）在使用之前通过机械操作来微量压裂海绵结构的部分，或（ii）形成在海绵结构的大部分上的表面浮雕图案 或（iii）在使用之前形成在海绵结构的主要部分中的流体入口通道的图案，或（iv）在海绵结构内浸渍片材。
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