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公开(公告)号:US20170106118A1
公开(公告)日:2017-04-20
申请号:US15338964
申请日:2016-10-31
Applicant: Sofradim Production
Inventor: Sébastien Ladet , Julien Claret
CPC classification number: A61L27/20 , A61K9/0024 , A61K45/00 , A61K47/36 , A61L27/24 , A61L27/48 , A61L27/54 , A61L27/56 , A61L27/58 , A61L2300/604 , A61L2430/00 , B05D5/00 , B32B37/24 , Y10T29/49947 , Y10T156/10 , C08L5/08
Abstract: Mono- and multi-layered implants include at least one porous layer made from a freeze dried aqueous solution containing chitosan, the solution having a pH of less than about 5.
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公开(公告)号:US20180243472A1
公开(公告)日:2018-08-30
申请号:US15963337
申请日:2018-04-26
Applicant: Sofradim Production
Inventor: Sébastien Ladet , Julien Claret
CPC classification number: A61L27/20 , A61K9/0024 , A61K45/00 , A61K47/36 , A61L27/24 , A61L27/48 , A61L27/54 , A61L27/56 , A61L27/58 , A61L2300/604 , A61L2430/00 , B05D5/00 , B32B37/24 , Y10T29/49947 , Y10T156/10 , C08L5/08
Abstract: Mono- and multi-layered implants include at least one porous layer made from a freeze dried aqueous solution containing chitosan, the solution having a pH of less than about 5.
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公开(公告)号:US10441678B2
公开(公告)日:2019-10-15
申请号:US15963337
申请日:2018-04-26
Applicant: Sofradim Production
Inventor: Sébastien Ladet , Julien Claret
IPC: A61L27/20 , A61K9/00 , A61K47/36 , A61L27/56 , A61K45/00 , B05D5/00 , B32B37/24 , A61L27/24 , A61L27/48 , A61L27/54 , A61L27/58
Abstract: Mono- and multi-layered implants include at least one porous layer made from a freeze dried aqueous solution containing chitosan, the solution having a pH of less than about 5.
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公开(公告)号:US10363690B2
公开(公告)日:2019-07-30
申请号:US14413499
申请日:2013-08-01
Applicant: Sofradim Production
Inventor: Sébastien Ladet , Sebastien Francois , Julien Claret , Maud Buffin
Abstract: Method for preparing a chitosan-based porous layer The present invention relates to a method or preparing a chitosan-based, neutralized compressed porous layer, comprising the following steps: —a) a chitosan solution is prepared, —b) said solution is poured into a mold in order to form a layer, —c) the layer obtained in b) is lyophilized so as to obtain a porous layer, —d) said porous layer obtained in c) is compressed, —e) the compressed porous layer obtained in d) is neutralized by means of an NH4OH solution. It also relates to an implant comprising a layer obtained according to such a method.
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公开(公告)号:US09981060B2
公开(公告)日:2018-05-29
申请号:US15338964
申请日:2016-10-31
Applicant: Sofradim Production
Inventor: Sébastien Ladet , Julien Claret
CPC classification number: A61L27/20 , A61K9/0024 , A61K45/00 , A61K47/36 , A61L27/24 , A61L27/48 , A61L27/54 , A61L27/56 , A61L27/58 , A61L2300/604 , A61L2430/00 , B05D5/00 , B32B37/24 , Y10T29/49947 , Y10T156/10 , C08L5/08
Abstract: Mono- and multi- layered implants include at least one porous layer made from a freeze dried aqueous solution containing chitosan, the solution having a pH of less than about 5.
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公开(公告)号:US09480774B2
公开(公告)日:2016-11-01
申请号:US14621519
申请日:2015-02-13
Applicant: Sofradim Production
Inventor: Sébastien Ladet , Julien Claret
IPC: A61K9/70 , A61L27/20 , A61K9/00 , A61K47/36 , A61L27/56 , A61K45/00 , B05D5/00 , B32B37/24 , A61L27/24 , A61L27/48 , A61L27/54 , A61L27/58
CPC classification number: A61L27/20 , A61K9/0024 , A61K45/00 , A61K47/36 , A61L27/24 , A61L27/48 , A61L27/54 , A61L27/56 , A61L27/58 , A61L2300/604 , A61L2430/00 , B05D5/00 , B32B37/24 , Y10T29/49947 , Y10T156/10 , C08L5/08
Abstract: Mono- and multi-layered implants include at least one porous layer made from a freeze dried aqueous solution containing chitosan, the solution having a pH of less than about 5.
Abstract translation: 单层和多层植入物包括由含有壳聚糖的冻干水溶液制成的至少一个多孔层,该溶液的pH值小于约5。
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公开(公告)号:US20150158209A1
公开(公告)日:2015-06-11
申请号:US14413499
申请日:2013-08-01
Applicant: Sofradim Production
Inventor: Sébastien Ladet , Sebastien Francois , Julien Claret , Maud Buffin
CPC classification number: B29C43/02 , A61B17/07292 , A61L27/20 , A61L27/50 , A61L27/56 , B29K2005/00 , B29L2007/00 , C08J9/28 , C08J2201/0504 , C08J2305/08 , C08L5/08
Abstract: Method for preparing a chitosan-based porous layer The present invention relates to a method or preparing a chitosan-based, neutralized compressed porous layer, comprising the following steps: —a) a chitosan solution is prepared, —b) said solution is poured into a mould in order to form a layer, —c) the layer obtained in b) is lyophilized so as to obtain a porous layer, —d) said porous layer obtained in c) is compressed, —e) the compressed porous layer obtained in d) is neutralized by means of an NH4OH solution. It also relates to an implant comprising a layer obtained according to such a method.
Abstract translation: 制备壳聚糖基多孔层的方法本发明涉及一种制备基于壳聚糖的中和的压缩多孔层的方法或方法,包括以下步骤:a)制备壳聚糖溶液,-b)将所述溶液倒入 为了形成层,将c)b)中获得的层冻干,以得到多孔层,-d)将c)中得到的多孔层压缩,-e)将得到的压缩多孔层 d)通过NH 4 OH溶液中和。 它还涉及包括根据这种方法获得的层的植入物。
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公开(公告)号:US20150157763A1
公开(公告)日:2015-06-11
申请号:US14621519
申请日:2015-02-13
Applicant: Sofradim Production
Inventor: Sébastien Ladet , Julien Claret
CPC classification number: A61L27/20 , A61K9/0024 , A61K45/00 , A61K47/36 , A61L27/24 , A61L27/48 , A61L27/54 , A61L27/56 , A61L27/58 , A61L2300/604 , A61L2430/00 , B05D5/00 , B32B37/24 , Y10T29/49947 , Y10T156/10 , C08L5/08
Abstract: Mono- and multi-layered implants include at least one porous layer made from a freeze dried aqueous solution containing chitosan, the solution having a pH of less than about 5.
Abstract translation: 单层和多层植入物包括由含有壳聚糖的冻干水溶液制成的至少一个多孔层,该溶液的pH值小于约5。
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