Systems and methods for removing gaseous micro emboli from blood

    公开(公告)号:US12280323B2

    公开(公告)日:2025-04-22

    申请号:US17688184

    申请日:2022-03-07

    Abstract: A system for removing gaseous micro emboli from blood prior to oxygenation. The system including a module having a blood inlet, a blood outlet, and a port configured to provide atmospheric or sub-atmospheric pressures, and microporous hollow fibers situated in the module and fluidly coupled to the port to provide the atmospheric or sub-atmospheric pressures inside the microporous hollow fibers. The module is configured to receive the blood through the blood inlet such that the blood flows from the blood inlet to the blood outlet around outside surfaces of the microporous hollow fibers such that at least some of the gaseous micro emboli in the blood are drawn from the blood through the microporous hollow fibers by the atmospheric or sub-atmospheric pressures.

    Elastic protection tube for a hollow fiber blood processing apparatus

    公开(公告)号:US10814056B2

    公开(公告)日:2020-10-27

    申请号:US15525853

    申请日:2014-11-12

    Abstract: A blood processing apparatus includes a housing, a shell, a fiber bundle, and an elastic tube. The housing has a blood inlet and a blood outlet and the shell is situated in the housing and configured to receive blood through the blood inlet. The shell includes a surface and one or more apertures extending through the surface to permit the blood to flow to an exterior of the shell. The fiber bundle includes gas exchanger hollow fibers situated about the shell such that gas flows through and the blood flows across the gas exchanger hollow fibers. The elastic tube includes a fiber web situated about the fiber bundle and configured to elastically constrain and protect the gas exchanger hollow fibers during the insertion into the housing. The fiber web has a pore size that permits the blood to flow across the fiber web without filtering micro-emboli from the blood.

    PURGER DEVICE FOR OXYGENATORS
    5.
    发明申请

    公开(公告)号:US20220168483A1

    公开(公告)日:2022-06-02

    申请号:US17675044

    申请日:2022-02-18

    Abstract: A purger device for hollow fiber oxygenators, including a gas inlet, a gas outlet, and a fluid communication feature between the gas inlet and the gas outlet. The purger device further including an accumulation chamber having a variable volume plenum ported to the fluid communication feature, and a flow control unit configured to vary fluid communication patterns in the fluid communication feature and having a first operating condition and a second operating condition, wherein in the first operating condition the flow control unit enables a fluid communication between the gas inlet and gas outlet, and wherein in the second operating condition the flow control unit enables a fluid communication between the gas inlet and the variable volume plenum of the accumulation chamber.

    SYSTEMS AND METHODS FOR REMOVING GASEOUS MICRO EMBOLI FROM BLOOD

    公开(公告)号:US20220184530A1

    公开(公告)日:2022-06-16

    申请号:US17688184

    申请日:2022-03-07

    Abstract: A system for removing gaseous micro emboli from blood prior to oxygenation. The system including a module having a blood inlet, a blood outlet, and a port configured to provide atmospheric or sub-atmospheric pressures, and microporous hollow fibers situated in the module and fluidly coupled to the port to provide the atmospheric or sub-atmospheric pressures inside the microporous hollow fibers. The module is configured to receive the blood through the blood inlet such that the blood flows from the blood inlet to the blood outlet around outside surfaces of the microporous hollow fibers such that at least some of the gaseous micro emboli in the blood are drawn from the blood through the microporous hollow fibers by the atmospheric or sub-atmospheric pressures.

    EXTRACORPOREAL BLOOD CONDITIONING DEVICES AND METHODS

    公开(公告)号:US20220409797A1

    公开(公告)日:2022-12-29

    申请号:US17903347

    申请日:2022-09-06

    Inventor: Andrea Zaniboni

    Abstract: A device for conditioning blood including a heat exchanger module including a heat exchanger fiber layer including heat exchanger fibers to receive a heat exchanger fluid and exchange heat with the blood, a gaseous micro-emboli removal module including a micro-porous fiber layer including micro-porous fibers to receive atmospheric or sub-atmospheric pressures such that at least some gaseous micro-emboli are drawn from the blood through the micro-porous fibers, a gas exchanger module including a gas exchanger fiber layer including gas exchanger fibers to receive a gas mixture and exchange gas with the blood, and a potting material body that embeds the heat exchanger fibers, the micro-porous fibers, and the gas exchanger fibers and defines a blood compartment that extends through the heat exchanger module, the gaseous micro-emboli removal module, and the gas exchanger module.

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