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公开(公告)号:US12280323B2
公开(公告)日:2025-04-22
申请号:US17688184
申请日:2022-03-07
Applicant: Sorin Group Italia S.r.l.
Inventor: Andrea Zaniboni , Stefano Spro , Claudio Silvestri
Abstract: A system for removing gaseous micro emboli from blood prior to oxygenation. The system including a module having a blood inlet, a blood outlet, and a port configured to provide atmospheric or sub-atmospheric pressures, and microporous hollow fibers situated in the module and fluidly coupled to the port to provide the atmospheric or sub-atmospheric pressures inside the microporous hollow fibers. The module is configured to receive the blood through the blood inlet such that the blood flows from the blood inlet to the blood outlet around outside surfaces of the microporous hollow fibers such that at least some of the gaseous micro emboli in the blood are drawn from the blood through the microporous hollow fibers by the atmospheric or sub-atmospheric pressures.
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公开(公告)号:US11994460B2
公开(公告)日:2024-05-28
申请号:US17545620
申请日:2021-12-08
Applicant: Sorin Group Italia S.r.l.
Inventor: Andrea Galavotti , Gabriele Tommasi , Giampaolo Simonini , Marco Luppi , Andrea Zaniboni , Paola Capriati
IPC: G01N21/03 , A61B5/1455 , G01N21/64 , A61B5/15
CPC classification number: G01N21/0303 , A61B5/14557 , G01N21/645 , A61B5/150992 , G01N2021/0367 , G01N2021/6432 , G01N2021/6482
Abstract: A system includes a cuvette including a cuvette body forming a substantially planar exterior surface and having a sensor window defined within the substantially planar exterior surface. The cuvette further includes a probe retention structure extending from the cuvette body. The system includes a probe with a probe body and a protrusion that is removably coupled to the probe retention structure.
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公开(公告)号:US10814056B2
公开(公告)日:2020-10-27
申请号:US15525853
申请日:2014-11-12
Applicant: Sorin Group Italia S.r.l.
Inventor: Andrea Zaniboni , Sara Menozzi , Francesco Benatti
Abstract: A blood processing apparatus includes a housing, a shell, a fiber bundle, and an elastic tube. The housing has a blood inlet and a blood outlet and the shell is situated in the housing and configured to receive blood through the blood inlet. The shell includes a surface and one or more apertures extending through the surface to permit the blood to flow to an exterior of the shell. The fiber bundle includes gas exchanger hollow fibers situated about the shell such that gas flows through and the blood flows across the gas exchanger hollow fibers. The elastic tube includes a fiber web situated about the fiber bundle and configured to elastically constrain and protect the gas exchanger hollow fibers during the insertion into the housing. The fiber web has a pore size that permits the blood to flow across the fiber web without filtering micro-emboli from the blood.
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公开(公告)号:US20230285737A1
公开(公告)日:2023-09-14
申请号:US17691777
申请日:2022-03-10
Applicant: Sorin Group Italia S.r.l.
Inventor: Andrea Zaniboni
IPC: A61M60/113 , A61M1/16 , A61M60/237 , A61M60/38 , A61M60/82 , A61M60/422
CPC classification number: A61M60/113 , A61M1/1698 , A61M60/237 , A61M60/38 , A61M60/422 , A61M60/82
Abstract: A blood conditioning assembly for use with an extracorporeal life support system may include an oxygenator including a housing and a gas exchanger disposed within the housing, and an axial pump extending from the housing and configured to drive fluid flow through the oxygenator. The axial pump may be integrally formed with the housing of the oxygenator. The blood conditioning assembly may be devoid of external tubing between the axial pump and the oxygenator.
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公开(公告)号:US20220168483A1
公开(公告)日:2022-06-02
申请号:US17675044
申请日:2022-02-18
Applicant: Sorin Group Italia S.r.l.
Inventor: Andrea Zaniboni , Claudio Silvestri
Abstract: A purger device for hollow fiber oxygenators, including a gas inlet, a gas outlet, and a fluid communication feature between the gas inlet and the gas outlet. The purger device further including an accumulation chamber having a variable volume plenum ported to the fluid communication feature, and a flow control unit configured to vary fluid communication patterns in the fluid communication feature and having a first operating condition and a second operating condition, wherein in the first operating condition the flow control unit enables a fluid communication between the gas inlet and gas outlet, and wherein in the second operating condition the flow control unit enables a fluid communication between the gas inlet and the variable volume plenum of the accumulation chamber.
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公开(公告)号:US20240272065A1
公开(公告)日:2024-08-15
申请号:US18643074
申请日:2024-04-23
Applicant: Sorin Group Italia S.r.l.
Inventor: Andrea Galavotti , Gabriele Tommasi , Giampaolo Simonini , Marco Luppi , Andrea Zaniboni , Paola Capriati
IPC: G01N21/03 , A61B5/1455 , A61B5/15 , G01N21/64
CPC classification number: G01N21/0303 , A61B5/14557 , G01N21/645 , A61B5/150992 , G01N2021/0367 , G01N2021/6432 , G01N2021/6482
Abstract: A system includes a cuvette including a cuvette body forming a substantially planar exterior surface and having a sensor window defined within the substantially planar exterior surface. The cuvette further includes a probe retention structure extending from the cuvette body. The system includes a probe with a probe body and a protrusion that is removably coupled to the probe retention structure.
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公开(公告)号:US20220184530A1
公开(公告)日:2022-06-16
申请号:US17688184
申请日:2022-03-07
Applicant: Sorin Group Italia S.r.l.
Inventor: Andrea Zaniboni , Stefano Spro , Claudio Silvestri
Abstract: A system for removing gaseous micro emboli from blood prior to oxygenation. The system including a module having a blood inlet, a blood outlet, and a port configured to provide atmospheric or sub-atmospheric pressures, and microporous hollow fibers situated in the module and fluidly coupled to the port to provide the atmospheric or sub-atmospheric pressures inside the microporous hollow fibers. The module is configured to receive the blood through the blood inlet such that the blood flows from the blood inlet to the blood outlet around outside surfaces of the microporous hollow fibers such that at least some of the gaseous micro emboli in the blood are drawn from the blood through the microporous hollow fibers by the atmospheric or sub-atmospheric pressures.
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公开(公告)号:US20220409797A1
公开(公告)日:2022-12-29
申请号:US17903347
申请日:2022-09-06
Applicant: Sorin Group Italia S.r.l.
Inventor: Andrea Zaniboni
Abstract: A device for conditioning blood including a heat exchanger module including a heat exchanger fiber layer including heat exchanger fibers to receive a heat exchanger fluid and exchange heat with the blood, a gaseous micro-emboli removal module including a micro-porous fiber layer including micro-porous fibers to receive atmospheric or sub-atmospheric pressures such that at least some gaseous micro-emboli are drawn from the blood through the micro-porous fibers, a gas exchanger module including a gas exchanger fiber layer including gas exchanger fibers to receive a gas mixture and exchange gas with the blood, and a potting material body that embeds the heat exchanger fibers, the micro-porous fibers, and the gas exchanger fibers and defines a blood compartment that extends through the heat exchanger module, the gaseous micro-emboli removal module, and the gas exchanger module.
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公开(公告)号:US20220099560A1
公开(公告)日:2022-03-31
申请号:US17545620
申请日:2021-12-08
Applicant: Sorin Group Italia S.r.l.
Inventor: Andrea Galavotti , Gabriele Tommasi , Giampaolo Simonini , Marco Luppi , Andrea Zaniboni , Paola Capriati
IPC: G01N21/03 , G01N21/64 , A61B5/1455
Abstract: A system includes a cuvette including a cuvette body forming a substantially planar exterior surface and having a sensor window defined within the substantially planar exterior surface. The cuvette further includes a probe retention structure extending from the cuvette body. The system includes a probe with a probe body and a protrusion that is removably coupled to the probe retention structure.
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公开(公告)号:US11226282B2
公开(公告)日:2022-01-18
申请号:US16309065
申请日:2016-06-15
Applicant: Sorin Group Italia S.r.l.
Inventor: Andrea Galavotti , Gabriele Tommasi , Giampaolo Simonini , Marco Luppi , Andrea Zaniboni , Paola Capriati
IPC: G01N21/03 , G01N21/64 , A61B5/1455 , A61B5/15
Abstract: A system includes a cuvette including a cuvette body forming a substantially planar exterior surface and having a sensor window defined within the substantially planar exterior surface. The cuvette further includes a probe retention structure extending from the cuvette body. The system includes a probe with a probe body and a protrusion that is removably coupled to the probe retention structure.
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