公开(公告)号：US09867695B2

公开(公告)日：2018-01-16

申请号：US13963191

申请日：2013-08-09

Applicant: Sorin Group Italia S.r.l.

Inventor： Carla Stacchino ,  Giovanni Bergamasco ,  Gaetano Burriesci

IPC: A61F2/24

CPC classification number: A61F2/2412 ,  A61F2/2418 ,  A61F2/2427 ,  A61F2250/0039

Abstract: A cardiac-valve prosthesis is adapted for percutaneous implantation. The prosthesis includes an armature adapted for deployment in a radially expanded implantation position, the armature including a support portion and an anchor portion, which are substantially axially coextensive with respect to one another. A set of leaflets is coupled to the support portion. The leaflets can be deployed with the armature in the implantation position. The leaflets define, in the implantation position, a flow duct that is selectably obstructable. The anchor portion can be deployed to enable anchorage of the cardiac-valve prosthesis at an implantation site.

公开(公告)号：US20170035565A1

公开(公告)日：2017-02-09

申请号：US15298516

申请日：2016-10-20

Applicant: Sorin Group Italia S.r.l.

Inventor： Carla Stacchino ,  Giovanni Bergamasco ,  Gaetano Burriesci ,  Giovanni Righini

IPC: A61F2/24 ,  A61F2/848

CPC classification number: A61F2/2418 ,  A61F2/2436 ,  A61F2/2469 ,  A61F2/848 ,  A61F2210/0014 ,  A61F2220/0008 ,  A61F2220/0075 ,  A61F2230/0054 ,  A61F2250/001 ,  Y10T29/49833

Abstract: A prosthesis for implantation at an implantation site proximate a native aortic valve, the implantation site including a valve annulus and a plurality of Valsalva sinuses located distal to the valve annulus. The prosthesis comprises an armature and a valve connected to the armature, wherein the armature includes a proximal portion configured for anchorage to the valve annulus, a distal portion configured to be positioned distal to the Valsalva sinuses when the proximal portion is anchored to the valve annulus, and first, second and third Valsalva sinus anchors each extending between and connecting the proximal and distal portions and arching radially outward between the proximal portion and the distal portion. The Valsalva sinus anchors are positioned so that each can extend into and engage a wall of a different one of the Valsalva sinuses

Abstract translation: 用于植入位于接近天然主动脉瓣的植入部位的假体，所述植入部位包括位于瓣膜环的远侧的瓣膜环和多个瓦萨尔瓦鼻窦。 所述假体包括电枢和连接到所述电枢的阀，其中所述电枢包括构造成用于锚固到所述瓣膜环的近端部分，所述近端部分构造成当所述近端部分被锚定到所述瓣膜环时被定位在所述Valsalva鼻窦的远侧 以及第一，第二和第三Valsalva窦锚，其各自在近端部分和远端部分之间延伸并连接，并且在近端部分和远端部分之间径向向外拱起。 Valsalva窦锚定位使得每个可以延伸进入和接合不同的Valsalva鼻窦的壁

公开(公告)号：US08920492B2

公开(公告)日：2014-12-30

申请号：US13972022

申请日：2013-08-21

Applicant: Sorin Group Italia S.r.l.

Inventor： Carla Stacchino ,  Giovanni Bergamasco ,  Gaetano Burriesci ,  Giovanni Righini

IPC: A61F2/24 ,  A61F11/00 ,  A61F2/848

CPC classification number: A61F2/2418 ,  A61F2/2436 ,  A61F2/2469 ,  A61F2/848 ,  A61F2210/0014 ,  A61F2220/0008 ,  A61F2220/0075 ,  A61F2230/0054 ,  A61F2250/001 ,  Y10T29/49833

Abstract: A method of repairing a native cardiac valve such as the aortic valve includes positioning a cardiac valve prosthesis at an implantation site proximate the native cardiac valve to be repaired. The cardiac valve prosthesis includes an armature and a plurality of prosthetic valve leaflets, the armature including first and second annular elements, a plurality of anchor members extending between the first and second annular elements, and a plurality of valve support members extending from at least one of the first and second annular elements, the plurality of prosthetic valve leaflets being coupled to and supported by the valve support members. The method further includes radially expanding the cardiac valve prosthesis such that each of the anchor members arches radially outward from the first annular element to the second annular element and engages a wall of a respective one of a plurality of native Valsalva sinuses located distal to the native cardiac valve so as to enable anchorage of the cardiac valve prosthesis at the implantation site.

Abstract translation: 修复诸如主动脉瓣的天然心脏瓣膜的方法包括将心脏瓣膜假体定位在靠近待修复的天然心脏瓣膜的植入部位。 所述心脏瓣膜假体包括电枢和多个假体瓣膜小叶，所述电枢包括第一和第二环形元件，在所述第一和第二环形元件之间延伸的多个锚定构件以及从至少一个 的第一和第二环形元件，所述多个人造瓣叶单元联接到阀支撑构件并由阀支撑构件支撑。 该方法还包括径向扩张心脏瓣膜假体，使得每个锚固构件从第一环形元件径向向外拱形到第二环形元件并且接合位于远离本地的多个天然瓦萨尔瓦鼻窦中的相应一个的壁 心脏瓣膜，以便能够在植入部位处锚定心脏瓣膜假体。

公开(公告)号：US09895223B2

公开(公告)日：2018-02-20

申请号：US15298516

申请日：2016-10-20

Applicant: Sorin Group Italia S.r.l.

Inventor： Carla Stacchino ,  Giovanni Bergamasco ,  Gaetano Burriesci ,  Giovanni Righini

IPC: A61F2/24 ,  A61F2/848

CPC classification number: A61F2/2418 ,  A61F2/2436 ,  A61F2/2469 ,  A61F2/848 ,  A61F2210/0014 ,  A61F2220/0008 ,  A61F2220/0075 ,  A61F2230/0054 ,  A61F2250/001 ,  Y10T29/49833

Abstract: A prosthesis for implantation at an implantation site proximate a native aortic valve, the implantation site including a valve annulus and a plurality of Valsalva sinuses located distal to the valve annulus. The prosthesis comprises an armature and a valve connected to the armature, wherein the armature includes a proximal portion configured for anchorage to the valve annulus, a distal portion configured to be positioned distal to the Valsalva sinuses when the proximal portion is anchored to the valve annulus, and first, second and third Valsalva sinus anchors each extending between and connecting the proximal and distal portions and arching radially outward between the proximal portion and the distal portion. The Valsalva sinus anchors are positioned so that each can extend into and engage a wall of a different one of the Valsalva sinuses.

公开(公告)号：US09486313B2

公开(公告)日：2016-11-08

申请号：US14548013

申请日：2014-11-19

Applicant: Sorin Group Italia S.r.l.

Inventor： Carla Stacchino ,  Giovanni Bergamasco ,  Gaetano Burriesci ,  Giovanni Righini

IPC: A61F2/24 ,  A61F2/848

CPC classification number: A61F2/2418 ,  A61F2/2436 ,  A61F2/2469 ,  A61F2/848 ,  A61F2210/0014 ,  A61F2220/0008 ,  A61F2220/0075 ,  A61F2230/0054 ,  A61F2250/001 ,  Y10T29/49833

Abstract: A method of repairing a native cardiac valve such as the aortic valve includes positioning a cardiac valve prosthesis at an implantation site proximate the native cardiac valve to be repaired. The cardiac valve prosthesis includes an armature and a plurality of prosthetic valve leaflets, the armature including first and second annular elements, a plurality of anchor members extending between the first and second annular elements, and a plurality of valve support members extending from at least one of the first and second annular elements, the plurality of prosthetic valve leaflets being coupled to and supported by the valve support members. The method further includes radially expanding the cardiac valve prosthesis such that each of the anchor members arches radially outward from the first annular element to the second annular element and engages a wall of a respective one of a plurality of native Valsalva sinuses located distal to the native cardiac valve so as to enable anchorage of the cardiac valve prosthesis at the implantation site.

Abstract translation: 修复诸如主动脉瓣的天然心脏瓣膜的方法包括将心脏瓣膜假体定位在靠近待修复的天然心脏瓣膜的植入部位。 所述心脏瓣膜假体包括电枢和多个假体瓣膜小叶，所述电枢包括第一和第二环形元件，在所述第一和第二环形元件之间延伸的多个锚定构件以及从至少一个 的第一和第二环形元件，所述多个人造瓣叶单元联接到阀支撑构件并由阀支撑构件支撑。 该方法还包括径向扩张心脏瓣膜假体，使得每个锚固构件从第一环形元件径向向外拱形到第二环形元件并且接合位于远离本地的多个天然瓦萨尔瓦鼻窦中的相应一个的壁 心脏瓣膜，以便能够在植入部位处锚定心脏瓣膜假体。

公开(公告)号：US20150148895A1

公开(公告)日：2015-05-28

申请号：US14548013

申请日：2014-11-19

Applicant: Sorin Group Italia S.r.l.

Inventor： Carla Stacchino ,  Giovanni Bergamasco ,  Gaetano Burriesci ,  Giovanni Righini

IPC: A61F2/24

CPC classification number: A61F2/2418 ,  A61F2/2436 ,  A61F2/2469 ,  A61F2/848 ,  A61F2210/0014 ,  A61F2220/0008 ,  A61F2220/0075 ,  A61F2230/0054 ,  A61F2250/001 ,  Y10T29/49833

Abstract: A method of repairing a native cardiac valve such as the aortic valve includes positioning a cardiac valve prosthesis at an implantation site proximate the native cardiac valve to be repaired. The cardiac valve prosthesis includes an armature and a plurality of prosthetic valve leaflets, the armature including first and second annular elements, a plurality of anchor members extending between the first and second annular elements, and a plurality of valve support members extending from at least one of the first and second annular elements, the plurality of prosthetic valve leaflets being coupled to and supported by the valve support members. The method further includes radially expanding the cardiac valve prosthesis such that each of the anchor members arches radially outward from the first annular element to the second annular element and engages a wall of a respective one of a plurality of native Valsalva sinuses located distal to the native cardiac valve so as to enable anchorage of the cardiac valve prosthesis at the implantation site.

Abstract translation: 修复诸如主动脉瓣的天然心脏瓣膜的方法包括将心脏瓣膜假体定位在靠近待修复的天然心脏瓣膜的植入部位。 所述心脏瓣膜假体包括电枢和多个假体瓣膜小叶，所述电枢包括第一和第二环形元件，在所述第一和第二环形元件之间延伸的多个锚定构件以及从至少一个 的第一和第二环形元件，所述多个人造瓣叶单元联接到阀支撑构件并由阀支撑构件支撑。 该方法还包括径向扩张心脏瓣膜假体，使得每个锚固构件从第一环形元件径向向外拱形到第二环形元件并且接合位于远离本地的多个天然瓦萨尔瓦鼻窦中的相应一个的壁 心脏瓣膜，以便能够在植入部位处锚定心脏瓣膜假体。

公开(公告)号：US20130325112A1

公开(公告)日：2013-12-05

申请号：US13963191

申请日：2013-08-09

Applicant: Sorin Group Italia S.r.l.

Inventor： Carla Stacchino ,  Giovanni Bergamasco ,  Gaetano Burriesci

IPC: A61F2/24

CPC classification number: A61F2/2412 ,  A61F2/2418 ,  A61F2/2427 ,  A61F2250/0039

Abstract: A cardiac-valve prosthesis is adapted for percutaneous implantation. The prosthesis includes an armature adapted for deployment in a radially expanded implantation position, the armature including a support portion and an anchor portion, which are substantially axially coextensive with respect to one another. A set of leaflets is coupled to the support portion. The leaflets can be deployed with the armature in the implantation position. The leaflets define, in the implantation position, a flow duct that is selectably obstructable. The anchor portion can be deployed to enable anchorage of the cardiac-valve prosthesis at an implantation site.

Abstract translation: 心脏瓣膜假体适用于经皮植入。 假体包括适于展开在径向扩张的植入位置的电枢，所述电枢包括支撑部分和锚定部分，所述支撑部分和锚定部分彼此基本轴向共延伸。 一组传单联接到支撑部分。 传单可以在植入位置上与衔铁一起展开。 在植入位置中，传单限定了可选择地阻塞的流动管道。 锚固部分​​可以被部署以使得能够在植入部位处锚定心脏瓣膜假体。