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公开(公告)号：US20210113755A1
公开(公告)日：2021-04-22
申请号：US16976428
申请日：2019-03-01
发明人： Scott Bowers , Stephen Turner , Jeremy Tamari
IPC分类号： A61M1/16
摘要： An oxygenator (10) for an extracorporeal ventilation system comprises a gas passage and a blood passage arranged to allow gas exchange of an oxygenation gas supply with blood via a gas-blood interface (34). The gas passage leads from a gas inlet zone (28) via the gas-blood interface (34) to a gas exhaust zone (40). The blood passage leads from a blood inlet (12) via the gas-blood interface (34) to a blood outlet (14). The oxygenator comprises a supply gas distribution arrangement (26, 28A, 28B). This allows the oxygenation gas supply to be modulated differently for different interface regions of the gas-blood interface. The oxygenator can be used to remove or reduce the formation of gaseous microemboli bubbles.
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公开(公告)号：US10806846B2
公开(公告)日：2020-10-20
申请号：US15763660
申请日：2016-09-08
发明人： Stephen Turner
IPC分类号： A61M1/36
摘要： A control system controlling the line pressure in a blood supply system (1) in which a pump (14) pumps blood from a reservoir (10) via a primary passage (18) toward a plurality of outlets (16, 26, 26a), wherein one or more outlets are openable to permit flow and closable to block flow, said control system comprises a monitoring arrangement to determine a line pressure in the primary passage, and a controller responsive to the monitoring arrangement and controlling the pump (14) to maintain the line pressure in the primary passage (18) above a pre-set level. The control system practically eliminates the risk of a momentary reduction in blood supply line pressure when an outlet is opened.
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公开(公告)号：US20200086034A1
公开(公告)日：2020-03-19
申请号：US16472194
申请日：2017-12-19
发明人： Stephen Turner
摘要： A control system is provided to restrict the flow rate of blood in a venous line 12 of a perfusion system 1 comprising a reservoir 10 supplied by the venous line 12 and supplying an outgoing line 22. The control system comprises an outgoing flow sensor 32 configured to determine an outgoing flow value indicative of the outgoing flow rate in the outgoing line 22, and a controller configured to process the outgoing flow value and to determine if the outgoing flow value exceeds a pre-set pairing threshold. The system further comprises an adjustable restriction 28 for restricting the flow rate in the venous line 12 to maintain a venous flow rate that does not exceed a venous restriction threshold, wherein the adjustable restriction 28 is responsive to the controller and wherein the controller comprises a configuration allowing the controller to set the adjustable restriction at the level of the outgoing flow rate, to change the venous restriction threshold with the outgoing flow rate, if the outgoing flow value is above the pre-set pairing threshold.
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公开(公告)号：US20180207348A1
公开(公告)日：2018-07-26
申请号：US15745896
申请日：2016-07-21
发明人： Stephen Turner
CPC分类号： A61M1/3664 , A61M1/101 , A61M1/14 , A61M1/3627 , A61M1/3666 , A61M39/281 , A61M2205/3334 , A61M2205/3355 , A61M2205/3386 , A61M2205/3389
摘要： A cardioplegic agent delivery system comprises a supply reservoir (40) for a cardioplegic agent carrier fluid, a delivery channel from the supply reservoir (40) to an outlet (48), and a pump (50) to flow the carrier liquid in the delivery channel above a minimum driving pressure. The supply reservoir (40) is configured to hold carrier fluid below the minimum driving pressure. The pump (50) is a centrifugal pump configured to receive carrier fluid from the supply reservoir (40) and to flow the carrier fluid to the outlet (48) at a flow rate and above the minimum driving pressure for the delivery of cardioplegic agent. This allows cardioplegia delivery to be managed better.
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公开(公告)号：US20190001047A1
公开(公告)日：2019-01-03
申请号：US16021433
申请日：2018-06-28
发明人： Stephen Turner
摘要： A flow control system of a clinical perfusion system comprises flow control devices 110, such as pumps, valves and/or clamps, capable of controlling a fluid flow rate according to flow rate parameters from the flow control system. The flow control system comprises an indicator arrangement including a device indicator 122a, 122b on each flow control device 110 capable of providing a plurality of indications. The device indicators 122a, 122b are controllable by the flow control system to indicate an active condition of the flow control device 110 independently of the flow rate parameters. This allows the indication provided by the device indicator 122a, 122b to be adjusted for different clinical environments, and to provide colour indications that match the colour range discernible by users affected by colour vision deficiency.
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公开(公告)号：US20180050146A1
公开(公告)日：2018-02-22
申请号：US15555765
申请日：2016-03-03
申请人： Spectrum Medical Ltd
发明人： Stephen Turner
CPC分类号： A61M1/1698 , A61M1/3609 , A61M1/3666 , A61M1/3667 , A61M2205/3331 , A61M2205/3334 , A61M2205/3368 , A61M2230/205
摘要： A blood gas analysis method (100) is provided for determining the partial pressure of oxygen of arterial blood exiting an oxygenator, wherein the oxygenator generates arterial blood by exposing venous blood to an oxygenation gas and releases excess oxygenation gas as exhaust gas. The method (100) comprises a step (140) of determining an estimate of the partial pressure of oxygen in the exhaust gas, a step (150) of determining the blood oxygen uptake in the oxygenator, and a step (160) of determining the partial pressure of oxygen in the arterial blood by adjusting the estimate using the blood oxygen uptake value. Used in a clinical setting, the method (100) allows a more accurate output of the partial pressure of oxygen in the arterial blood to be provided, which facilitates oxygenator operation.
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公开(公告)号：US20230079577A1
公开(公告)日：2023-03-16
申请号：US17794487
申请日：2020-11-27
发明人： Stephen Turner
IPC分类号： A61M60/546 , A61M1/36 , A61M60/113 , A61M60/38
摘要： A control system for a perfusion system (1), the control system being configured to control a plurality of blood flow rates in the perfusion system during a weaning phase. The perfusion system comprises: a first blood line (26) in which blood is permitted to flow at a first flow rate; a second blood line (34) in which blood is permitted to flow at a second flow rate; an arterial blood line (22) in which blood is permitted to flow at an arterial flow rate; and an arterial pump (20) configured to circulate blood at the arterial flow rate in the arterial blood line. The control system comprises a controller configured to determine the first flow rate and the second flow rate and to process the first and second flow rates to determine a desired arterial flow rate. The controller is configured to operate in a first mode in which the controller modulates operation of the arterial pump (20) to adjust the arterial flow rate so that the arterial flow rate matches the desired arterial flow rate.
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公开(公告)号：US11376412B2
公开(公告)日：2022-07-05
申请号：US16080565
申请日：2017-02-28
发明人： Stephen Turner
IPC分类号： A61M39/28
摘要： A clamping mechanism (30) for clamping a flexible tube comprises two rotatable bobbins (22, 32), each with a tube-engaging surface portion (24) defining boundaries of a free space through which a tube may extend. The shape of the tube-engaging surface portion (24) changes around the bobbin circumference, such that axial rotation of the bobbins (22, 32) reduces the free space and thereby squeezes the tube. This allows the flow through the tube to be altered dependent on the rotation of the bobbins.
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公开(公告)号：US20210154389A1
公开(公告)日：2021-05-27
申请号：US16629664
申请日：2018-07-17
摘要： A heater-cooler apparatus of an extracorporeal perfusion system comprises at least one fluid circuit (102, 104) providing a supply of a heat transfer fluid to the perfusion system, a cold storage unit (266), and a refrigeration unit (250) for charging the cold storage unit (266). The cold storage unit (266) comprises a chamber (312) containing a liquid that freezes at a temperature above that to which the heat transfer fluid is cooled by the refrigeration unit (250), and a passage through which the heat transfer fluid is conveyed, the passage extending through the chamber (312). This allows a more effective cold storage unit to be provided.
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公开(公告)号：US20200345914A1
公开(公告)日：2020-11-05
申请号：US16856386
申请日：2020-04-23
申请人： Spectrum Medical Ltd
发明人： Stephen Turner
摘要： A gas supply control system for an oxygenator of an extracorporeal ventilation system is configured for connection to external gas supply ports for oxygen and nitrogen in the form of air and to create a supply gas output from oxygen and nitrogen. The gas supply control system comprises two or more gas output lines and configured to supply the two or more gas output lines with the supply gas output. The flow rates through the gas output lines may be modulated differently.
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