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1.发明申请DIPHENYLAMINE-SUBSTITUTED SALICYLTHIAZOLE DERIVATIVES AND RELATED COMPOUNDS AS PHOSPHOTYROSINE PHOSPHATASE 1B (PTB1B) INHIBITORS FOR USING AS BLOOD-SUGAR DECREASING ACTIVE INGREDIENTS FOR TREATING DIABETES 有权二苯胺取代的三甲基噻唑衍生物及相关化合物作为磷酸二氢吡啶磷酸酯1B（PTB1B）抑制剂，用于治疗糖尿病的血糖减少活性成分公开(公告)号：US20070191441A1
公开(公告)日：2007-08-16
申请号：US11609463
申请日：2006-12-12
IPC分类号： A61K31/426
CPC分类号： C07D277/42 , C07D277/46
摘要： The invention therefore relates to compounds of the formula I in which the variables are as defined in the specification, to pharmaceutical compositions containing them and to their use for therapeutically lowering blood glucose levels.
摘要翻译： 因此，本发明涉及式I化合物，其中变量如说明书中所定义，含有它们的药物组合物及其用于治疗降低血糖水平的用途。
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2.发明申请SUBSTITUTED OXAZOLOBENZOISOTHIAZOLE DIOXIDE DERIVATIVES METHOD FOR PRODUCTION AND USE THEREOF 有权取代的氧杂环丁烷二唑二氧化物衍生物生产方法及其用途公开(公告)号：US20070149511A1
公开(公告)日：2007-06-28
申请号：US11560602
申请日：2006-11-16
IPC分类号： A61K31/541 , A61K31/5377 , A61K31/496 , A61K31/454 , A61K31/4245 , C07D417/14 , C07D413/14
CPC分类号： C07D417/14 , C07D417/12
摘要： The invention relates to compounds of formula (I), where the groups have the meanings set forth herein and the physiologically-acceptable salts thereof. The compounds are suitable as medicaments for lowering blood sugar levels and for prevention and treatment of diabetes.
摘要翻译： 本发明涉及式（I）化合物，其中基团具有本文所述的含义及其生理上可接受的盐。 该化合物适用于降低血糖水平和预防和治疗糖尿病的药物。
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3.发明授权Substituted oxazolobenzoisothiazole dioxide derivatives method for production and use thereof 有权取代的氧杂二氮杂异噻唑二氧化物衍生物的制备方法及其用途公开(公告)号：US07453000B2
公开(公告)日：2008-11-18
申请号：US11560602
申请日：2006-11-16
IPC分类号： C07D275/04 , A01N43/80
CPC分类号： C07D417/14 , C07D417/12
摘要： The invention relates to compounds of formula (I), where the groups have the meanings set forth herein and the physiologically-acceptable salts thereof. The compounds are suitable as medicaments for lowering blood sugar levels and for prevention and treatment of diabetes.
摘要翻译： 本发明涉及式（I）化合物，其中基团具有本文所述的含义及其生理上可接受的盐。 该化合物适用于降低血糖水平和预防和治疗糖尿病的药物。
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4.发明授权Diphenylamine-substituted salicylthiazole derivatives and related compounds as phosphotyrosine phosphatase 1B (PTB1B) inhibitors for using as blood-sugar decreasing active ingredients for treating diabetes 有权二苯胺取代的水杨基噻唑衍生物和相关化合物作为磷酸降解活性成分用于治疗糖尿病的磷酸酪氨酸磷酸酶1B（PTB1B）抑制剂公开(公告)号：US07741491B2
公开(公告)日：2010-06-22
申请号：US11609463
申请日：2006-12-12
IPC分类号： A61K31/426 , C07D277/42
CPC分类号： C07D277/42 , C07D277/46
摘要： The invention therefore relates to compounds of the formula I in which the variables are as defined in the specification, to pharmaceutical compositions containing them and to their use for therapeutically lowering blood glucose levels.
摘要翻译： 因此，本发明涉及式I化合物，其中变量如说明书中所定义，含有它们的药物组合物及其用于治疗降低血糖水平的用途。
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5.发明授权Imidazopyridine derivatives, process for preparation thereof and therapeutic use thereof 有权咪唑并吡啶衍生物，其制备方法及其治疗用途公开(公告)号：US08759344B2
公开(公告)日：2014-06-24
申请号：US13808503
申请日：2011-07-04
IPC分类号： A61K31/53 , C07D401/00 , C07D413/00 , A61K31/517 , A61K9/20 , C07D211/82 , C07D471/04 , C07D233/88 , C07D211/90 , C07D233/64 , A61K45/06 , A61K31/5377 , C07D233/90
CPC分类号： A61K31/517 , A61K9/2018 , A61K9/2054 , A61K9/2059 , A61K31/437 , A61K31/5377 , A61K45/06 , C07D211/82 , C07D211/90 , C07D233/64 , C07D233/88 , C07D233/90 , C07D471/04
摘要： The invention relates to compounds corresponding to formula (I): in which R2 and R3 together form, with the carbon atoms of the phenyl nucleus to which they are attached, a 6-membered nitrogenous heterocycle corresponding to one of formula (A), (B) or (C) below: in which the wavy lines represent the phenyl nucleus to which R2 and R3 are attached. Preparation process and therapeutic use.
摘要翻译： 本发明涉及对应于式（I）的化合物：其中R 2和R 3一起与它们所连接的苯基的碳原子一起形成对应于式（A），（A）中的一个的6-元含氮杂环， B）或（C）：其中波浪线表示R2和R3所连接的苯基核。 制备过程和治疗用途。
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6.发明申请IMIDAZOPYRIDINE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND THERAPEUTIC USE THEREOF 有权咪唑吡啶衍生物，其制备方法及其治疗用途公开(公告)号：US20130116250A1
公开(公告)日：2013-05-09
申请号：US13808503
申请日：2011-07-04
IPC分类号： A61K31/5377 , A61K31/517 , A61K45/06 , C07D471/04
CPC分类号： A61K31/517 , A61K9/2018 , A61K9/2054 , A61K9/2059 , A61K31/437 , A61K31/5377 , A61K45/06 , C07D211/82 , C07D211/90 , C07D233/64 , C07D233/88 , C07D233/90 , C07D471/04
摘要： The invention relates to compounds corresponding to formula (I): in which R2 and R3 together form, with the carbon atoms of the phenyl nucleus to which they are attached, a 6-membered nitrogenous heterocycle corresponding to one of formula (A), (B) or (C) below: in which the wavy lines represent the phenyl nucleus to which R2 and R3 are attached.Preparation process and therapeutic use.
摘要翻译： 本发明涉及对应于式（I）的化合物：其中R 2和R 3一起与它们所连接的苯基的碳原子一起形成对应于式（A），（A）中的一个的6-元含氮杂环， B）或（C）：其中波浪线表示R2和R3所连接的苯基核。 制备过程和治疗用途。
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公开(公告)号：US07481620B2
公开(公告)日：2009-01-27
申请号：US11260138
申请日：2005-10-28
申请人： Reinhard Kirsch , Siegfried Derrer
发明人： Reinhard Kirsch , Siegfried Derrer
IPC分类号： F03D11/00
CPC分类号： F16C33/58 , F03D80/70 , F05B2260/80 , F05B2260/90 , F16C19/166 , F16C33/78 , F16C41/007 , F16C2300/14 , F16C2360/31 , G01P3/443 , G01P3/487 , Y02B10/30 , Y02E10/722
摘要： A wind power plant comprises an outside ring, an inside ring and roll bodies arranged between an inside jacket of the outside ring and an outside jacket of the inside ring for permitting twisting or rotation of the bearing rings against one another. One of the rings on the jacket comprises an auxiliary sensor at least along a portion of the periphery. The auxiliary sensor together with the primary sensor provided in the other bearing ring are configured in such a way that a twisting or rotational position of the two bearing rings relative to one another can be detected.
摘要翻译： 风力发电设备包括外环，内环和辊体，其布置在外环的内护套和内环的外护套之间，用于允许轴承环彼此扭转或旋转。 护套上的一个环包括至少沿着周边的一部分的辅助传感器。 辅助传感器与设置在另一个轴承环中的主传感器一起被构造成使得可以检测到两个轴承环的扭转或旋转位置相对于彼此。
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8.发明授权Method of treatment with combinations of statin and aryl-substituted propanolamine derivatives 有权用他汀类药物和芳基取代的丙醇胺衍生物联合治疗的方法公开(公告)号：US06897198B2
公开(公告)日：2005-05-24
申请号：US10351317
申请日：2003-01-27
IPC分类号： C07D213/74 , A61K31/44 , A61K31/4402 , A61K31/4436 , A61K31/4439 , A61K31/444 , A61K31/675 , A61K31/7028 , A61K31/706 , A61K38/00 , A61P3/00 , A61P3/06 , A61P9/10 , C07D413/14 , C07D417/14 , C07H5/06 , C07H15/18 , C07H15/26 , C07K4/00 , A61K31/70
CPC分类号： C07H15/18
摘要： Substituted propanolamine derivatives, their pharmaceutically tolerated salts and physiologically functional derivatives thereof are described.Also described are compounds of formula I in which the radicals have the abovementioned meanings, and their physiologically tolerated salts, physiologically functional derivates and processes for their preparation. The compounds are suitable as, for example, hypolipidemics.
摘要翻译： 描述了取代的丙醇胺衍生物，其药学上可耐受的盐及其生理功能衍生物。 还描述了其中基团具有上述含义的式I化合物及其生理上耐受的盐，生理功能衍生物及其制备方法。 该化合物适合作为例如降血脂药。
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9.发明授权Combinations with statin and aryl-substituted propanolamine derivatives, their preparation pharmaceuticals comprising them, and their use 有权与他汀类和芳基取代的丙醇胺衍生物的组合，它们的制备，包含它们的药物及其用途公开(公告)号：US06569835B2
公开(公告)日：2003-05-27
申请号：US09985149
申请日：2001-11-01
IPC分类号： A61K3170
CPC分类号： C07H15/18
摘要： Substituted propanolamine derivatives, their pharmaceutically tolerated salts and physiologically functional derivatives thereof are described. Also described are compounds of formula I in which the radicals have the abovementioned meanings, and their physiologically tolerated salts, physiologically functional derivates and processes for their preparation. The compounds are suitable as, for example, hypolipidemics.
摘要翻译： 描述了取代的丙醇胺衍生物，其药学上可耐受的盐及其生理功能衍生物。 还描述了具有上述含义的基团的式Iin化合物及其生理学耐受的盐，生理功能衍生物及其制备方法。 该化合物适合作为例如降血脂药。
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10.发明授权Substituted quinoline derivatives, a process for their preparation, and their use 失效取代的喹啉衍生物，其制备方法及其用途
公开(公告)号：US5798365A
公开(公告)日：1998-08-25
申请号：US515556
申请日：1995-08-14
IPC分类号： A61K31/47 , A61P31/12 , A61P31/18 , C07D215/22 , C07D215/227 , C07D215/24 , C07D215/26 , C07D215/36 , C07D215/38 , C07D215/58 , C07D221/20 , C07D401/06 , C07D401/12 , C07D401/14
CPC分类号： C07D215/227 , C07D215/22 , C07D215/26 , C07D215/36 , C07D215/38 , C07D221/20 , C07D401/06 , C07D401/12
摘要： Compounds of the formula I, ##STR1## and also their tautomeric forms of the formula Ia, ##STR2## in which the substituents R.sup.1 to R.sup.6 and X have said meanings, exhibit antiviral activity.
摘要翻译： 式Ⅰ化合物，（Ⅰ）化合物及其互变异构形式的式Ia，其中取代基R 1至R 6和X具有所述含义，具有抗病毒活性。
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