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公开(公告)号:US20100041135A1
公开(公告)日:2010-02-18
申请号:US12503774
申请日:2009-07-15
申请人: Stephen F. Badylak , George B. Boder , Sherry L. Voytik-Harbin , Matthew S. Waninger , Andrew O. Brightman
发明人: Stephen F. Badylak , George B. Boder , Sherry L. Voytik-Harbin , Matthew S. Waninger , Andrew O. Brightman
IPC分类号: C12N5/07
CPC分类号: G01N33/56922 , C12N1/20 , C12N5/0068 , C12N2533/92 , G01N33/5091 , Y10S435/851
摘要: A cell culture growth substrate comprising submucosal tissue of a warm-blooded vertebrate and a method for culturing fastidious organisms is described. Submucosal tissue used in accordance with the present invention supports the proliferation of cells when said cells are contacted with submucosal tissue under conditions conducive to cell proliferation.
摘要翻译: 描述了包含温血脊椎动物的粘膜下组织的细胞培养生长底物和培养有害生物的方法。 当在有利于细胞增殖的条件下,当所述细胞与粘膜下组织接触时,根据本发明使用的粘膜下组织支持细胞的增殖。
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公开(公告)号:US08647677B2
公开(公告)日:2014-02-11
申请号:US12503774
申请日:2009-07-15
CPC分类号: G01N33/56922 , C12N1/20 , C12N5/0068 , C12N2533/92 , G01N33/5091 , Y10S435/851
摘要: A cell culture growth substrate comprising submucosal tissue of a warm-blooded vertebrate and a method for culturing fastidious organisms is described. Submucosal tissue used in accordance with the present invention supports the proliferation of cells when said cells are contacted with submucosal tissue under conditions conducive to cell proliferation.
摘要翻译: 描述了包含温血脊椎动物的粘膜下组织的细胞培养生长底物和培养有害生物的方法。 当在有利于细胞增殖的条件下,当所述细胞与粘膜下组织接触时,根据本发明使用的粘膜下组织支持细胞的增殖。
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公开(公告)号:US08597342B2
公开(公告)日:2013-12-03
申请号:US12195762
申请日:2008-08-21
IPC分类号: A61F2/06
CPC分类号: A61F2/07 , A61F2/89 , A61F2002/061 , A61F2002/075 , A61F2250/0017
摘要: The disclosure relates to an implantable woven graft for bridging a defect in a main vessel near one or more branch vessels. The graft includes a region of reduced yarn density. Reduced yarn density regions are alignable with at least one of the one or more branch vessels, and are suitable for in situ fenestration, for example by perforation. The disclosed examples are particularly suited for bridging abdominal aortic aneurysms.
摘要翻译: 本公开涉及一种用于桥接在一个或多个分支血管附近的主血管中的缺损的可植入机织移植物。 移植物包括纱线密度降低的区域。 减少的纱线密度区域可以与一个或多个分支血管中的至少一个对准,并且适合于原位开窗,例如通过穿孔。 所公开的实施例特别适用于桥接腹主动脉瘤。
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公开(公告)号:US20090157164A1
公开(公告)日:2009-06-18
申请号:US12195762
申请日:2008-08-21
IPC分类号: A61F2/06
CPC分类号: A61F2/07 , A61F2/89 , A61F2002/061 , A61F2002/075 , A61F2250/0017
摘要: The disclosure relates to an implantable woven graft for bridging a defect in a main vessel near one or more branch vessels. The graft includes a region of reduced yarn density. Reduced yarn density regions are alignable with at least one of the one or more branch vessels, and are suitable for in situ fenestration, for example by perforation. The disclosed examples are particularly suited for bridging abdominal aortic aneurysms.
摘要翻译: 本公开涉及一种用于桥接在一个或多个分支血管附近的主血管中的缺损的可植入机织移植物。 移植物包括纱线密度降低的区域。 减少的纱线密度区域可以与一个或多个分支血管中的至少一个对准,并且适合于原位开窗,例如通过穿孔。 所公开的实施例特别适用于桥接腹主动脉瘤。
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公开(公告)号:US06565597B1
公开(公告)日:2003-05-20
申请号:US09617352
申请日:2000-07-17
IPC分类号: A61F206
CPC分类号: A61F2/07 , A61F2/848 , A61F2/95 , A61F2002/075 , A61F2002/9511 , A61F2220/0016 , A61F2220/0075 , A61F2230/005 , A61F2230/0054 , A61F2230/0067
摘要: An expandable stent prosthesis is disclosed in which the apices of the bends located at at least one end of the stent are individually twisted at an angle to the circumference of the stent to form a fan blade-like arrangement when viewed from that end. The fan blade-like arrangement allows the stent to expand from the compressed condition during deployment such that likelihood of a strut or bend of the stent become entangled with a barb or adjacent strut or bend, is reduced. In one embodiment of the invention, the fan blade-like arrangement results from plastically deforming the individual apices, while in another embodiment, the apices are twisted into the fan blade-like arrangement during the loading process, such as by use of a suture thread to pull the apices into alignment.
摘要翻译: 公开了一种可扩张的支架假体,其中位于支架的至少一端的弯曲的顶点在从该端观察时以与支架的圆周成一定角度单独扭转以形成扇形叶片状布置。 风扇叶片状布置允许支架在展开期间从压缩状态膨胀,使得支架的支柱或弯曲部的可能性变得与倒钩或相邻的支柱或弯曲部缠结。 在本发明的一个实施例中,风扇叶片状结构是由于各个顶点的塑性变形,而在另一个实施例中,顶点在加载过程中被扭曲成风扇叶片状布置,例如通过使用缝合线 将顶点拉平。
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