公开(公告)号：US20110282270A1

公开(公告)日：2011-11-17

申请号：US12779137

申请日：2010-05-13

申请人： Steven G. Hall ,  John A. Hibner ,  Julia J. Hwang ,  Yolanda F. Carter

发明人： Steven G. Hall ,  John A. Hibner ,  Julia J. Hwang ,  Yolanda F. Carter

IPC分类号： A61B17/32 ,  A61M37/00

CPC分类号： A61B17/0057 ,  A61B17/00491 ,  A61B17/12099 ,  A61B17/12186 ,  A61B2017/00641 ,  A61L27/225 ,  A61L27/3683 ,  A61L2400/06 ,  A61M5/19

摘要： A tissue treatment device comprises a housing having a chamber that receives a treatment fluid mixture of tissue morsels and a scaffold material. A debriding shaft including a plurality of cutters is coupled with the housing. The debriding shaft extends proximally within the chamber and extends distally from the end of the housing. The debriding shaft is inserted within a treatment site such as a fistula tract and is rotated and reciprocated such that the debriding shaft removes tissue cells along the site. The site is flushed with saline or other irrigating fluid followed by application of the treatment fluid mixture. The chamber of the housing comprises agitators positioned adjacent the debriding shaft. The treatment fluid mixture passes through the chamber of the housing along and between the outer surface of the debriding shaft and the agitators for thorough mixing before exiting the device at the treatment site.

摘要翻译： 组织处理装置包括具有容纳组织小块和支架材料的处理流体混合物的腔室的壳体。 包括多个切割器的清创轴与壳体联接。 清创轴在腔室内向近侧延伸并且从壳体的端部向远侧延伸。 清创轴插入治疗部位如瘘管，并且被旋转和往复运动，使得清除轴沿着部位去除组织细胞。 用盐水或其他冲洗液冲洗部位，然后施用治疗液混合物。 外壳的腔室包括邻近清创轴定位的搅拌器。 治疗液混合物沿着清除轴的外表面和搅拌器之间通过壳体的腔室，以便在处理部位离开装置之前进行充分混合。

公开(公告)号：US08702644B2

公开(公告)日：2014-04-22

申请号：US12779137

申请日：2010-05-13

申请人： Steven G. Hall ,  John A. Hibner ,  Julia J. Hwang ,  Yolanda F. Carter

发明人： Steven G. Hall ,  John A. Hibner ,  Julia J. Hwang ,  Yolanda F. Carter

IPC分类号： A61B17/20 ,  A61B17/32 ,  A61B17/00 ,  A61B17/22 ,  A61D1/02

CPC分类号： A61B17/0057 ,  A61B17/00491 ,  A61B17/12099 ,  A61B17/12186 ,  A61B2017/00641 ,  A61L27/225 ,  A61L27/3683 ,  A61L2400/06 ,  A61M5/19

摘要： A tissue treatment device comprises a housing having a chamber that receives a treatment fluid mixture of tissue morsels and a scaffold material. A debriding shaft including a plurality of cutters is coupled with the housing. The debriding shaft extends proximally within the chamber and extends distally from the end of the housing. The debriding shaft is inserted within a treatment site such as a fistula tract and is rotated and reciprocated such that the debriding shaft removes tissue cells along the site. The site is flushed with saline or other irrigating fluid followed by application of the treatment fluid mixture. The chamber of the housing comprises agitators positioned adjacent the debriding shaft. The treatment fluid mixture passes through the chamber of the housing along and between the outer surface of the debriding shaft and the agitators for thorough mixing before exiting the device at the treatment site.

摘要翻译： 组织处理装置包括具有容纳组织小块和支架材料的处理流体混合物的腔室的壳体。 包括多个切割器的清创轴与壳体联接。 清创轴在腔室内向近侧延伸并且从壳体的端部向远侧延伸。 清创轴插入治疗部位如瘘管，并且被旋转和往复运动，使得清除轴沿着部位去除组织细胞。 用盐水或其他冲洗液冲洗部位，然后施用治疗液混合物。 外壳的腔室包括邻近清创轴定位的搅拌器。 治疗液混合物沿着清除轴的外表面和搅拌器之间通过壳体的腔室，以便在处理部位离开装置之前进行充分混合。

公开(公告)号：US08464925B2

公开(公告)日：2013-06-18

申请号：US12777449

申请日：2010-05-11

申请人： Joanne Hull ,  Wells D. Haberstich ,  Steven G. Hall ,  John A. Hibner ,  Julia J. Hwang ,  Yolanda F. Carter ,  Frederick E. Shelton, IV ,  John B. Schulte ,  Rebecca J. Mollere ,  Patrick D. Dugan ,  Michael D. Cronin ,  Jerome R. Morgan

发明人： Joanne Hull ,  Wells D. Haberstich ,  Steven G. Hall ,  John A. Hibner ,  Julia J. Hwang ,  Yolanda F. Carter ,  Frederick E. Shelton, IV ,  John B. Schulte ,  Rebecca J. Mollere ,  Patrick D. Dugan ,  Michael D. Cronin ,  Jerome R. Morgan

IPC分类号： A61B17/04 ,  A61B17/10

CPC分类号： A61B17/115 ,  A61B17/00491 ,  A61B17/07292 ,  A61B17/1155 ,  A61B50/30 ,  A61B2017/00889 ,  A61B2017/00893 ,  A61B2050/314

摘要： A surgical stapler includes first and second tissue clamping members and a reservoir configured to hold a tissue treatment composition. The first tissue clamping member is configured to receive a plurality of staples. The second tissue clamping member comprises an anvil configured to form the staples. The reservoir may be provided in a handle portion of the surgical stapler, and a fluid conduit may be used to communicate the tissue treatment composition from the reservoir. An end effector lumen may selectively communicate with the fluid conduit. The lumen may also be in communication with openings to further communicate the tissue treatment composition to tissue or to a scaffold material positioned adjacent to tissue. A reservoir may alternatively be provided in one of the clamping members. A knife member may pierce a housing defining the reservoir, and a resilient member may then urge a tissue treatment composition from the housing.

摘要翻译： 手术吻合器包括第一和第二组织夹紧构件和构造成保持组织处理组合物的储存器。 第一组织夹紧构件构造成容纳多个钉。 第二组织夹紧构件包括构造成形成钉的砧座。 储存器可以设置在外科缝合器的手柄部分中，并且流体导管可用于将组织处理组合物与储存器连通。 末端执行器腔可以选择性地与流体导管连通。 内腔还可以与开口连通，以进一步将组织处理组合物传递到组织或邻近组织定位的支架材料。 也可以在一个夹紧构件中设置储存器。 刀构件可以刺穿限定储存器的壳体，并且弹性构件然后可以从壳体推动组织处理组合物。

公开(公告)号：US20110282368A1

公开(公告)日：2011-11-17

申请号：US12778587

申请日：2010-05-12

申请人： Jeffrey S. Swayze ,  Foster B. Stulen ,  Mark H. Ransick ,  Steven G. Hall ,  John A. Hibner ,  Julia J. Hwang ,  Yolanda F. Carter ,  Frederick E. Shelton, IV

发明人： Jeffrey S. Swayze ,  Foster B. Stulen ,  Mark H. Ransick ,  Steven G. Hall ,  John A. Hibner ,  Julia J. Hwang ,  Yolanda F. Carter ,  Frederick E. Shelton, IV

IPC分类号： A61B17/22 ,  A61B17/00

CPC分类号： A61B17/0057 ,  A61B10/0283 ,  A61B17/00491 ,  A61B17/32002 ,  A61B17/320758 ,  A61B18/1492 ,  A61B2017/00623 ,  A61B2017/00641 ,  A61B2017/00654 ,  A61B2017/00867 ,  A61B2017/00893 ,  A61B2017/00969 ,  A61B2017/22067 ,  A61B2017/320064 ,  A61B2217/005 ,  A61B2217/007 ,  A61M1/0084

摘要： A fistula repair system includes a debriding member that may be inserted into a fistula to debride the fistula wall. The debriding member may include a plurality of selectively extendable barbs. The barbs may be hollow to deliver a medical fluid within the fistula. The debriding member may also include a plurality of openings configured to communicate the medical fluid within the fistula. The barbs may extend through the openings. The openings may include associated protrusions that are configured to debride the fistula wall. The medical fluid may include a slurry of tissue and a scaffold material. The tissue in the slurry may comprise minced tissue that was harvested from the patient afflicted with the fistula. A balloon may be used to at least temporarily seal one end of the fistula. An RF probe or mechanical hook member may be used to seal the other end of the fistula.

摘要翻译： 瘘修复系统包括可以插入瘘管以清除瘘管壁的清创构件。 清创构件可以包括多个可选择性地可延伸的倒钩。 倒钩可以是中空的，以在瘘管内输送医用流体。 解围构件还可以包括多个开口，其被构造成在瘘管内传送医用流体。 倒钩可以延伸穿过开口。 开口可以包括被配置为清除瘘管壁的相关联的突起。 医用流体可以包括组织和支架材料的浆液。 浆液中的组织可以包括从患有瘘​​管的患者收获的切碎的组织。 可以使用气囊来至少临时密封瘘的一端。 可以使用RF探针或机械钩构件来密封瘘的另一端。

公开(公告)号：US20110282337A1

公开(公告)日：2011-11-17

申请号：US12778671

申请日：2010-05-12

申请人： Steven G. Hall ,  John A. Hibner ,  Julia J. Hwang ,  Yolanda F. Carter

发明人： Steven G. Hall ,  John A. Hibner ,  Julia J. Hwang ,  Yolanda F. Carter

IPC分类号： A61B18/18 ,  A61B17/3205

CPC分类号： A61B17/00491 ,  A61B10/0266 ,  A61B10/0283 ,  A61B17/0057 ,  A61B17/32002 ,  A61B18/1492 ,  A61B2017/00398 ,  A61B2017/00623 ,  A61B2017/00641 ,  A61B2017/00654 ,  A61B2017/00893 ,  A61B2017/00969 ,  A61B2017/320004 ,  A61B2017/320775 ,  A61B2018/1472 ,  A61B2217/005 ,  A61B2217/007 ,  A61M1/0084

摘要： A treatment system comprises an outer sheath and an end effector. The end effector has a plurality of cutting features, at least a portion of which are configured to debride a tissue surface when the end effector is actuated. The cutting features may also be configured to harvest tissue. A medical fluid reservoir is in fluid communication with the end effector, such that the end effector may deliver a medical fluid to a target site such as a fistula. The medical fluid may include harvested tissue cells and a scaffold material. A vacuum cannula may be positioned coaxially within the interior cavity of the end effector, and an RF probe may be positioned co-axially within the interior cavity of the vacuum cannula. The vacuum cannula and RF probe may be used together to seal a fistula in which medical fluid has been dispensed.

摘要翻译： 治疗系统包括外鞘和末端执行器。 末端执行器具有多个切割特征，其至少一部分被配置为当端部执行器被致动时清除组织表面。 切割特征也可以被配置成收获组织。 医疗液体储存器与末端执行器流体连通，使得末端执行器可将医疗流体输送到诸如瘘的目标部位。 医疗流体可以包括收获的组织细胞和支架材料。 真空插管可以同轴地定位在端部执行器的内部空腔内，并且RF探针可以同轴地定位在真空插管的内部空腔内。 真空插管和RF探针可以一起使用以密封已经分配了药液的瘘管。

公开(公告)号：US08858546B2

公开(公告)日：2014-10-14

申请号：US12778671

申请日：2010-05-12

申请人： Steven G. Hall ,  John A. Hibner ,  Julia J. Hwang ,  Yolanda F. Carter

发明人： Steven G. Hall ,  John A. Hibner ,  Julia J. Hwang ,  Yolanda F. Carter

IPC分类号： A61B18/18 ,  A61B10/02 ,  A61B17/00 ,  A61B17/32 ,  A61B18/14 ,  A61B17/3207 ,  A61M1/00

CPC分类号： A61B17/00491 ,  A61B10/0266 ,  A61B10/0283 ,  A61B17/0057 ,  A61B17/32002 ,  A61B18/1492 ,  A61B2017/00398 ,  A61B2017/00623 ,  A61B2017/00641 ,  A61B2017/00654 ,  A61B2017/00893 ,  A61B2017/00969 ,  A61B2017/320004 ,  A61B2017/320775 ,  A61B2018/1472 ,  A61B2217/005 ,  A61B2217/007 ,  A61M1/0084

摘要： A treatment system comprises an outer sheath and an end effector. The end effector has a plurality of cutting features, at least a portion of which are configured to debride a tissue surface when the end effector is actuated. The cutting features may also be configured to harvest tissue. A medical fluid reservoir is in fluid communication with the end effector, such that the end effector may deliver a medical fluid to a target site such as a fistula. The medical fluid may include harvested tissue cells and a scaffold material. A vacuum cannula may be positioned coaxially within the interior cavity of the end effector, and an RF probe may be positioned co-axially within the interior cavity of the vacuum cannula. The vacuum cannula and RF probe may be used together to seal a fistula in which medical fluid has been dispensed.

摘要翻译： 治疗系统包括外鞘和末端执行器。 末端执行器具有多个切割特征，其至少一部分被配置为当端部执行器被致动时清除组织表面。 切割特征也可以被配置成收获组织。 医疗液体储存器与末端执行器流体连通，使得末端执行器可以将医疗流体输送到诸如瘘的目标部位。 医疗流体可以包括收获的组织细胞和支架材料。 真空插管可以同轴地定位在端部执行器的内部空腔内，并且RF探针可以同轴地定位在真空插管的内部空腔内。 真空插管和RF探针可以一起使用以密封已经分配了药液的瘘管。

公开(公告)号：US20110278346A1

公开(公告)日：2011-11-17

申请号：US12777449

申请日：2010-05-11

申请人： Joanne Hull ,  Wells D. Haberstich ,  Steven G. Hall ,  John A. Hibner ,  Julia J. Hwang ,  Yolanda F. Carter ,  Frederick E. Shelton, IV ,  John B. Schulte ,  Rebecca J. Mollere ,  Patrick D. Dugan ,  Michael D. Cronin ,  Jerome R. Morgan

发明人： Joanne Hull ,  Wells D. Haberstich ,  Steven G. Hall ,  John A. Hibner ,  Julia J. Hwang ,  Yolanda F. Carter ,  Frederick E. Shelton, IV ,  John B. Schulte ,  Rebecca J. Mollere ,  Patrick D. Dugan ,  Michael D. Cronin ,  Jerome R. Morgan

IPC分类号： A61B17/068 ,  A61F2/02

CPC分类号： A61B17/115 ,  A61B17/00491 ,  A61B17/07292 ,  A61B17/1155 ,  A61B50/30 ,  A61B2017/00889 ,  A61B2017/00893 ,  A61B2050/314

摘要： A surgical stapler includes first and second tissue clamping members and a reservoir configured to hold a tissue treatment composition. The first tissue clamping member is configured to receive a plurality of staples. The second tissue clamping member comprises an anvil configured to form the staples. The reservoir may be provided in a handle portion of the surgical stapler, and a fluid conduit may be used to communicate the tissue treatment composition from the reservoir. An end effector lumen may selectively communicate with the fluid conduit. The lumen may also be in communication with openings to further communicate the tissue treatment composition to tissue or to a scaffold material positioned adjacent to tissue. A reservoir may alternatively be provided in one of the clamping members. A knife member may pierce a housing defining the reservoir, and a resilient member may then urge a tissue treatment composition from the housing.

摘要翻译： 手术吻合器包括第一和第二组织夹紧构件和构造成保持组织处理组合物的储存器。 第一组织夹紧构件构造成容纳多个钉。 第二组织夹紧构件包括构造成形成钉的砧座。 储存器可以设置在外科缝合器的手柄部分中，并且流体导管可用于将组织处理组合物与储存器连通。 末端执行器腔可以选择性地与流体导管连通。 内腔还可以与开口连通，以进一步将组织处理组合物传递到组织或邻近组织定位的支架材料。 也可以在一个夹紧构件中设置储存器。 刀构件可以刺穿限定储存器的壳体，并且弹性构件然后可以从壳体推动组织处理组合物。