公开(公告)号：US20180071343A1

公开(公告)日：2018-03-15

申请号：US15815668

申请日：2017-11-16

申请人： Stewart Abbot ,  James Edinger ,  Aleksander Francki ,  Robert J. Hariri ,  Vladimir Jankovic ,  Aleksandr Kaplunovsky ,  Kristen Labazzo ,  Eric Law ,  Neerav Padliya ,  Jennifer Paredes ,  Jia-Lun Wang

发明人： Stewart Abbot ,  James Edinger ,  Aleksander Francki ,  Robert J. Hariri ,  Vladimir Jankovic ,  Aleksandr Kaplunovsky ,  Kristen Labazzo ,  Eric Law ,  Neerav Padliya ,  Jennifer Paredes ,  Jia-Lun Wang

IPC分类号： A61K35/50 ,  A61L27/38 ,  A61K35/28 ,  A61K9/00 ,  A61L27/36 ,  C12N5/073

CPC分类号： A61K35/50 ,  A61K9/0019 ,  A61K9/0085 ,  A61K35/28 ,  A61L27/3633 ,  A61L27/3683 ,  A61L27/3808 ,  A61L27/3834 ,  A61L27/3886 ,  A61L27/3895 ,  C12N5/0605 ,  A61K2300/00

摘要： Provided herein are methods of treating individuals having diseases or disorders of the circulatory system, using placental cells, e.g., the placental stem cells and placental multipotent cells (PDACs) described herein, and populations of such placental cells. The invention also provides methods of angiogenesis using such cells or populations of cells comprising such cells.

公开(公告)号：US20150238566A1

公开(公告)日：2015-08-27

申请号：US14557419

申请日：2014-12-01

申请人： Neerav Padliya ,  Robert J. Hariri ,  Carlon Colker

发明人： Neerav Padliya ,  Robert J. Hariri ,  Carlon Colker

IPC分类号： A61K38/17

CPC分类号： A61K38/1703 ,  A23L15/00 ,  A23L33/17 ,  A23V2002/00 ,  A61K35/57 ,  A23V2250/542 ,  A23V2200/316 ,  A61K2300/00 ,  A61K38/1709

摘要： Embodiments of the present invention are generally related to methods of obtaining effective amount of avian follistatin. More specifically, embodiments of the present invention relate to products comprising avian follistatin, and methods of optimizing the same based on avian follistatin concentrations utilized during the manufacturing process. In one embodiment of the present invention, a method of creating a consumable product for treatment of a muscle degenerating disease having avian follistatin comprises selecting an avian egg based upon a desired threshold of avian follistatin concentration therein; extracting material from the avian egg, the material comprising avian follistatin; and processing the material with one or more excipients to yield the consumable product.

摘要翻译： 本发明的实施方案通常涉及获得有效量的禽卵泡抑素的方法。 更具体地，本发明的实施方案涉及包含禽类卵泡抑素的产品，以及基于在制造过程中使用的禽类卵泡抑素浓度的优化方法。 在本发明的一个实施方案中，一种产生用于治疗具有鸟类卵泡抑素的肌肉退化疾病的消耗品的方法包括：根据所需的禽卵泡抑素浓度阈值选择禽卵; 从鸟类卵中提取物质，该材料包括鸟类卵泡抑素; 并用一种或多种赋形剂处理该材料以产生消耗品。