摘要:
A corner protector and bulkhead protector for a cargo carrying vehicle such as a rail car are formed to have deep channels or corrugations that provide for both increased strength and rigidity while also providing support for load restraining web straps.
摘要:
The invention is to a compound exhibiting neurokinin inhibitory properties, a pharmaceutical composition comprising same and a method of treatment for neurokinin-mediated conditions.
摘要:
The present invention relates to a method of treating disorders of the Central Nervous System (CNS) and other disorders in a mammal, including a human, by administering to the mammal a CNS-penetrant α7 nicotinic receptor agonist. It also relates to pharmaceutical compositions containing a pharmaceutically acceptable carrier and a CNS-penetrant α7 nicotinic receptor agonist.
摘要:
In one embodiment, an initial series of bytes are scanned to determine a frequency of occurrence within the initial series of bytes for a plurality of byte strings. A data structure is generated containing the plurality of byte strings and count values representing a frequency of occurrence for the plurality of byte strings in the initial series of bytes. A most common byte string of the plurality of byte strings in the initial series of bytes is determined from the count values. Each instance of the most common byte string in the initial series of bytes is replaced with a first substitute byte string to form a revised series of bytes. A most common byte string in the revised series of bytes is determined from the data structure without resetting the count values associated with at least some of the plurality of byte strings.
摘要:
The present invention relates to a method of treating disorders of the central nervous system (CNS) and other disorders in a mammal, including a human, by administering to the mammal a CNS-penetrant α7 nicotinic receptor agonist. It also relates to pharmaceutical compositions containing a pharmaceutically acceptable carrier and a CNS-penetrant α7 nicotinic receptor agonist.
摘要:
The present invention provides a compound having the structure of formula I: wherein R1 is hydrogen, (C1-C6) alkyl, unconjugated (C3-C6) alkenyl, benzyl, YC(═O)(C1-C6) alkyl or —CH2CH2—O—(C1-C4) alkyl; X is CH2 or CH2CH2; Y is (C2-C6) alkylene; Z is (CH2)m, CF2, or C(═O), where m is 0, 1 or 2; R2 and R3 are selected independently from hydrogen, halogen, —(C1-C6) alkyl optionally substituted with from 1 to 7 halogen atoms, and —O(C1-C6) alkyl optionally substituted with from 1 to 7 halogen atoms, or R2 and R3 each together with the atom to which it is connected independently form C(═O), S→O, S(═O)2, or N→O; and is a 5- to 7-membered monocyclic heteroaryl group selected from pyridinyl, pyridone, pyridazinyl, imidazolyl, pyrimidinyl, pyrazolyl, triazolyl, pyrazinyl, furyl, thienyl, isoxazolyl, thiazolyl, oxazolyl, isothiazolyl, pyrrolyl, cinnolinyl, triazinyl, oxadiazolyl, thiadiazolyl and furazanyl groups.
摘要:
Techniques for generating and vending of unique sequence values are described. Each master of a ring of masters is configured to create and vend the unique sequence values downstream to filling pools for eventual client consumption. When a ring of masters is employed, each master communicates with one another to agree on a current range of values that should next be vended. A master may then vend these values to a layer of one or more filling pools, at least of which includes or has access to persistent and non-persistent storage memories.
摘要:
A method of updating computer software includes identifying an orphaned computer file in a second version of computer software, the orphaned computer file having a name that does not correspond to any name of a computer file in a first version of computer software and computing symmetric divergence between the orphaned computer file and each computer file in the first version of computer software. The method also includes choosing a file from the computer files in the first version of computer software that yields a minimum value of symmetric divergence between the file and the orphaned computer file and using the file as a reference file for compressing the orphaned computer file.
摘要:
In one embodiment, an initial series of bytes are scanned to determine a frequency of occurrence within the initial series of bytes for a plurality of byte strings. A data structure is generated containing the plurality of byte strings and count values representing a frequency of occurrence for the plurality of byte strings in the initial series of bytes. A most common byte string of the plurality of byte strings in the initial series of bytes is determined from the count values. Each instance of the most common byte string in the initial series of bytes is replaced with a first substitute byte string to form a revised series of bytes. A most common byte string in the revised series of bytes is determined from the data structure without resetting the count values associated with at least some of the plurality of byte strings.
摘要:
A method of updating computer software includes identifying an orphaned computer file in a second version of computer software, the orphaned computer file having a name that does not correspond to any name of a computer file in a first version of computer software and computing symmetric divergence between the orphaned computer file and each computer file in the first version of computer software. The method also includes choosing a file from the computer files in the first version of computer software that yields a minimum value of symmetric divergence between the file and the orphaned computer file and using the file as a reference file for compressing the orphaned computer file.