公开(公告)号：US20070031845A1

公开(公告)日：2007-02-08

申请号：US10750622

申请日：2003-12-31

申请人： Sue DeNise ,  Paul Charteris ,  David Rosenfeld ,  Tom Holm ,  Stephen Bates

发明人： Sue DeNise ,  Paul Charteris ,  David Rosenfeld ,  Tom Holm ,  Stephen Bates

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6881 ,  C12Q1/6827 ,  C12Q1/6876 ,  C12Q1/6883 ,  C12Q1/6888 ,  C12Q2600/124 ,  C12Q2600/156 ,  C12Q2600/16 ,  C12Q2600/172 ,  Y02A90/26

摘要： Provided herein are methods to discover and use single nucleotide polymorphisms (SNP) for identifying breed, or line and breed, or line composition of a bovine subject. The present invention further provides specific nucleic acid sequences, SNPs, and SNP patterns that can be used for identifying breed or breed combinations for Angus, Holstein, Limousin, Brahman, Hereford, Simmental, Gelbvieh, Charolais and Beefmaster breeds. These patterns can be utilized to manage animals in a feedlot to obtain optimum performance based on known characteristics of specific breeds and identify animals for breeding in selection programs. In another aspect, these patterns can be used to ensure labeling on breed specific branded products.

摘要翻译： 本文提供了发现和使用单核苷酸多态性（SNP）来鉴定牛受试者的品种，品系或品系或品系的方法。 本发明还提供可用于鉴定安格斯，荷斯坦，利摩赞，婆罗门，赫里福德，西门塔尔，格尔维耶，夏洛来和牛肉品种的品种或品种组合的特异性核酸序列，SNP和SNP模式。 这些模式可以用于在饲养场中管理动物以基于特定品种的已知特征获得最佳性能，并鉴定用于选择程序中育种的动物。 另一方面，这些模式可用于确保品种特定品牌产品的标签。

公开(公告)号：US08026064B2

公开(公告)日：2011-09-27

申请号：US12148507

申请日：2008-04-18

申请人： Sue K. DeNise ,  Paul Charteris ,  David Rosenfeld ,  Tom Holm ,  Stephen Bates

发明人： Sue K. DeNise ,  Paul Charteris ,  David Rosenfeld ,  Tom Holm ,  Stephen Bates

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6881 ,  C12Q1/6827 ,  C12Q1/6876 ,  C12Q1/6883 ,  C12Q1/6888 ,  C12Q2600/124 ,  C12Q2600/156 ,  C12Q2600/16 ,  C12Q2600/172 ,  Y02A90/26

摘要： Provided herein are methods to discover and use single nucleotide polymorphisms (SNP) for identifying breed, or line and breed, or line composition of a bovine subject. The present invention further provides specific nucleic acid sequences, SNPs, and SNP patterns that can be used for identifying breed or breed combinations for Angus, Holstein, Limousin, Brahman, Hereford, Simmental, Gelbvieh, Charolais and Beefmaster breeds. These patterns can be utilized to manage animals in a feedlot to obtain optimum performance based on known characteristics of specific breeds and identify animals for breeding in selection programs. In another aspect, these patterns can be used to ensure labeling on breed specific branded products.

摘要翻译： 本文提供了发现和使用单核苷酸多态性（SNP）来鉴定牛受试者的品种，品系或品系或品系的方法。 本发明还提供可用于鉴定安格斯，荷斯坦，利摩赞，婆罗门，赫里福德，西门塔尔，格尔维耶，夏洛来和牛肉品种的品种或品种组合的特异性核酸序列，SNP和SNP模式。 这些模式可以用于在饲养场中管理动物以基于特定品种的已知特征获得最佳性能，并鉴定用于选择程序中育种的动物。 另一方面，这些模式可用于确保品种特定品牌产品的标签。

公开(公告)号：US20090221432A1

公开(公告)日：2009-09-03

申请号：US12148507

申请日：2008-04-18

申请人： Sue K. DeNise ,  Paul Charteris ,  David Rosenfeld ,  Tom Holm ,  Stephen Bates

发明人： Sue K. DeNise ,  Paul Charteris ,  David Rosenfeld ,  Tom Holm ,  Stephen Bates

IPC分类号： C40B30/04 ,  C12Q1/68 ,  C40B40/06

CPC分类号： C12Q1/6881 ,  C12Q1/6827 ,  C12Q1/6876 ,  C12Q1/6883 ,  C12Q1/6888 ,  C12Q2600/124 ,  C12Q2600/156 ,  C12Q2600/16 ,  C12Q2600/172 ,  Y02A90/26

摘要： Provided herein are methods to discover and use single nucleotide polymorphisms (SNP) for identifying breed, or line and breed, or line composition of a bovine subject. The present invention further provides specific nucleic acid sequences, SNPs, and SNP patterns that can be used for identifying breed or breed combinations for Angus, Holstein, Limousin, Brahman, Hereford, Simmental, Gelbvieh, Charolais and Beefmaster breeds. These patterns can be utilized to manage animals in a feedlot to obtain optimum performance based on known characteristics of specific breeds and identify animals for breeding in selection programs. In another aspect, these patterns can be used to ensure labeling on breed specific branded products.

摘要翻译： 本文提供了发现和使用单核苷酸多态性（SNP）来鉴定牛受试者的品种，品系或品系或品系的方法。 本发明还提供可用于鉴定安格斯，荷斯坦，利摩赞，婆罗门，赫里福德，西门塔尔，格尔维耶，夏洛来和牛肉品种的品种或品种组合的特异性核酸序列，SNP和SNP模式。 这些模式可以用于在饲养场中管理动物以基于特定品种的已知特征获得最佳性能，并鉴定用于选择程序中育种的动物。 另一方面，这些模式可用于确保品种特定品牌产品的标签。

公开(公告)号：US07511127B2

公开(公告)日：2009-03-31

申请号：US10750622

申请日：2003-12-31

申请人： Sue K. DeNise ,  Paul Charteris ,  David Rosenfeld ,  Tom Holm ,  Stephen Bates

发明人： Sue K. DeNise ,  Paul Charteris ,  David Rosenfeld ,  Tom Holm ,  Stephen Bates

IPC分类号： C12N15/11 ,  C12N15/63 ,  C12N1/21 ,  C07H21/04 ,  C12Q1/68

CPC分类号： C12Q1/6881 ,  C12Q1/6827 ,  C12Q1/6876 ,  C12Q1/6883 ,  C12Q1/6888 ,  C12Q2600/124 ,  C12Q2600/156 ,  C12Q2600/16 ,  C12Q2600/172 ,  Y02A90/26

摘要： Provided herein are methods to discover and use single nucleotide polymorphisms (SNP) for identifying breed, or line and breed, or line composition of a bovine subject. The present invention further provides specific nucleic acid sequences, SNPs, and SNP patterns that can be used for identifying breed or breed combinations for Angus, Holstein, Limousin, Brahman, Hereford, Simmental, Gelbvieh, Charolais and Beefmaster breeds. These patterns can be utilized to manage animals in a feedlot to obtain optimum performance based on known characteristics of specific breeds and identify animals for breeding in selection programs. In another aspect, these patterns can be used to ensure labeling on breed specific branded products.

公开(公告)号：US20080268454A1

公开(公告)日：2008-10-30

申请号：US12069845

申请日：2008-02-13

申请人： Sue K. DeNise ,  Paul Charteris ,  David Rosenfeld ,  Tom Holm ,  Stephen Bates

发明人： Sue K. DeNise ,  Paul Charteris ,  David Rosenfeld ,  Tom Holm ,  Stephen Bates

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6881 ,  C12Q1/6827 ,  C12Q1/6876 ,  C12Q1/6883 ,  C12Q1/6888 ,  C12Q2600/124 ,  C12Q2600/156 ,  C12Q2600/16 ,  C12Q2600/172 ,  Y02A90/26

摘要： Methods, compositions, and systems are provided for managing bovine subjects in order to maximize their individual potential performance and edible meat value, and to maximize profits obtained in marketing the bovine subjects. The methods and systems draw an inference of a trait of a bovine subject by determining the nucleotide occurrence of at least one bovine SNP that is identified herein as being associated with the trait. The inference is used in methods of the present invention to establish the economic value of a bovine subject, to improve profits related to selling beef from a bovine subject; to manage bovine subjects, to sort bovine subjects; to improve the genetics of a bovine population by selecting and breeding of bovine subjects, to clone a bovine subject with a specific trait, to track meat or another commercial product of a bovine subject; and to diagnose a health condition of a bovine subject. Methods are also disclosed for identifying additional SNPs associated with a trait, by using the associated SNPs identified herein.

摘要翻译： 提供方法，组成和系统用于管理牛科目，以最大限度地发挥其个人潜在的表现和可食用的肉类价值，并最大限度地利用牛市场营销中获得的利润。 方法和系统通过确定本文鉴定为与性状相关联的至少一种牛SNP的核苷酸发生来引出牛受试者的性状的推断。 推论用于本发明的方法，以建立牛科目的经济价值，以提高从牛科学家出售牛肉的利润; 管理牛科目，分类牛科目; 通过选择和育种牛科目以克隆具有特定性状的牛受试者来追踪牛或其他商品的牛群体来改善牛种群的遗传学; 并诊断牛受试者的健康状况。 还公开了通过使用本文鉴定的相关SNP来鉴定与性状相关的另外的SNP的方法。

公开(公告)号：US08669056B2

公开(公告)日：2014-03-11

申请号：US13220174

申请日：2011-08-29

申请人： Sue K. DeNise ,  Paul Charteris ,  David Rosenfeld ,  Tom Holm ,  Stephen Bates

发明人： Sue K. DeNise ,  Paul Charteris ,  David Rosenfeld ,  Tom Holm ,  Stephen Bates

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6881 ,  C12Q1/6827 ,  C12Q1/6876 ,  C12Q1/6883 ,  C12Q1/6888 ,  C12Q2600/124 ,  C12Q2600/156 ,  C12Q2600/16 ,  C12Q2600/172 ,  Y02A90/26

摘要： Provided herein are methods to discover and use single nucleotide polymorphisms (SNP) for identifying breed, or line and breed, or line composition of a bovine subject. The present invention further provides specific nucleic acid sequences, SNPs, and SNP patterns that can be used for identifying breed or breed combinations for Angus, Holstein, Limousin, Brahman, Hereford, Simmental, Gelbvieh, Charolais and Beefmaster breeds. These patterns can be utilized to manage animals in a feedlot to obtain optimum performance based on known characteristics of specific breeds and identify animals for breeding in selection programs. In another aspect, these patterns can be used to ensure labeling on breed specific branded products.

摘要翻译： 本文提供了发现和使用单核苷酸多态性（SNP）来鉴定牛受试者的品种，品系或品系或品系的方法。 本发明还提供可用于鉴定安格斯，荷斯坦，利摩赞，婆罗门，赫里福德，西门塔尔，格尔维耶，夏洛来和牛肉品种的品种或品种组合的特异性核酸序列，SNP和SNP模式。 这些模式可以用于在饲养场中管理动物以基于特定品种的已知特征获得最佳性能，并鉴定用于选择程序中育种的动物。 另一方面，这些模式可用于确保品种特定品牌产品的标签。

公开(公告)号：US20120090040A1

公开(公告)日：2012-04-12

申请号：US13220174

申请日：2011-08-29

申请人： Sue K. DeNise ,  Paul Charteris ,  David Rosenfeld ,  Tom Holm ,  Stephen Bates

发明人： Sue K. DeNise ,  Paul Charteris ,  David Rosenfeld ,  Tom Holm ,  Stephen Bates

IPC分类号： C40B20/00 ,  A01K67/027

CPC分类号： C12Q1/6881 ,  C12Q1/6827 ,  C12Q1/6876 ,  C12Q1/6883 ,  C12Q1/6888 ,  C12Q2600/124 ,  C12Q2600/156 ,  C12Q2600/16 ,  C12Q2600/172 ,  Y02A90/26

摘要： Provided herein are methods to discover and use single nucleotide polymorphisms (SNP) for identifying breed, or line and breed, or line composition of a bovine subject. The present invention further provides specific nucleic acid sequences, SNPs, and SNP patterns that can be used for identifying breed or breed combinations for Angus, Holstein, Limousin, Brahman, Hereford, Simmental, Gelbvieh, Charolais and Beefmaster breeds. These patterns can be utilized to manage animals in a feedlot to obtain optimum performance based on known characteristics of specific breeds and identify animals for breeding in selection programs. In another aspect, these patterns can be used to ensure labeling on breed specific branded products.

摘要翻译： 本文提供了发现和使用单核苷酸多态性（SNP）来鉴定牛受试者的品种，品系或品系或品系的方法。 本发明还提供可用于鉴定安格斯，荷斯坦，利摩赞，婆罗门，赫里福德，西门塔尔，格尔维耶，夏洛来和牛肉品种的品种或品种组合的特异性核酸序列，SNP和SNP模式。 这些模式可以用于在饲养场中管理动物以基于特定品种的已知特征获得最佳性能，并鉴定用于选择程序中育种的动物。 另一方面，这些模式可用于确保品种特定品牌产品的标签。

公开(公告)号：US07709206B2

公开(公告)日：2010-05-04

申请号：US12069845

申请日：2008-02-13

申请人： Sue K. DeNise ,  Paul Charteris ,  David Rosenfeld ,  Tom Holm ,  Stephen Bates

发明人： Sue K. DeNise ,  Paul Charteris ,  David Rosenfeld ,  Tom Holm ,  Stephen Bates

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6881 ,  C12Q1/6827 ,  C12Q1/6876 ,  C12Q1/6883 ,  C12Q1/6888 ,  C12Q2600/124 ,  C12Q2600/156 ,  C12Q2600/16 ,  C12Q2600/172 ,  Y02A90/26

摘要： Methods, compositions, and systems are provided for managing bovine subjects in order to maximize their individual potential performance and edible meat value, and to maximize profits obtained in marketing the bovine subjects. The methods and systems draw an inference of a trait of a bovine subject by determining the nucleotide occurrence of at least one bovine SNP that is identified herein as being associated with the trait. The inference is used in methods of the present invention to establish the economic value of a bovine subject, to improve profits related to selling beef from a bovine subject; to manage bovine subjects, to sort bovine subjects; to improve the genetics of a bovine population by selecting and breeding of bovine subjects, to clone a bovine subject with a specific trait, to track meat or another commercial product of a bovine subject; and to diagnose a health condition of a bovine subject. Methods are also disclosed for identifying additional SNPs associated with a trait, by using the associated SNPs identified herein.

摘要翻译： 提供方法，组成和系统用于管理牛科目，以最大限度地发挥其个人潜在的表现和可食用的肉类价值，并最大限度地利用牛市场营销中获得的利润。 方法和系统通过确定本文鉴定为与性状相关联的至少一种牛SNP的核苷酸发生来引出牛受试者的性状的推断。 推论用于本发明的方法，以建立牛科目的经济价值，以提高从牛科学家出售牛肉的利润; 管理牛科目，分类牛科目; 通过选择和育种牛科目以克隆具有特定性状的牛受试者来追踪牛或其他商品的牛群体来改善牛种群的遗传学; 并诊断牛受试者的健康状况。 还公开了通过使用本文鉴定的相关SNP来鉴定与性状相关的另外的SNP的方法。

公开(公告)号：US20050287531A1

公开(公告)日：2005-12-29

申请号：US10750623

申请日：2003-12-31

申请人： Sue DeNise ,  Richard Kerr ,  David Rosenfeld ,  Tom Holm ,  Stephen Bates ,  Dennis Fantin

发明人： Sue DeNise ,  Richard Kerr ,  David Rosenfeld ,  Tom Holm ,  Stephen Bates ,  Dennis Fantin

IPC分类号： C07H21/04 ,  C12Q1/68

CPC分类号： C12Q1/6881 ,  C12Q1/6827 ,  C12Q1/6876 ,  C12Q1/6883 ,  C12Q1/6888 ,  C12Q2600/124 ,  C12Q2600/156 ,  C12Q2600/16 ,  C12Q2600/172 ,  Y02A90/26

摘要： Methods, compositions, and systems are provided for managing bovine subjects in order to maximize their individual potential performance and edible meat value, and to maximize profits obtained in marketing the bovine subjects. The methods and systems draw an inference of a trait of a bovine subject by determining the nucleotide occurrence of at least one bovine SNP that is identified herein as being associated with the trait. The inference is used in methods of the present invention to establish the economic value of a bovine subject, to improve profits related to selling beef from a bovine subject; to manage bovine subjects, to sort bovine subjects; to improve the genetics of a bovine population by selecting and breeding of bovine subjects, to clone a bovine subject with a specific trait, to track meat or another commercial product of a bovine subject; and to diagnose a health condition of a bovine subject. Methods are also disclosed for identifying additional SNPs associated with a trait, by using the associated SNPs identified herein.

摘要翻译： 提供方法，组成和系统用于管理牛科目，以最大限度地发挥其个人潜在的表现和可食用的肉类价值，并最大限度地利用牛市场营销中获得的利润。 方法和系统通过确定本文鉴定为与性状相关联的至少一种牛SNP的核苷酸发生来引出牛受试者的性状的推断。 推论用于本发明的方法，以建立牛科目的经济价值，以提高从牛科学家出售牛肉的利润; 管理牛科目，分类牛科目; 通过选择和育种牛科目以克隆具有特定性状的牛受试者来追踪牛或其他商品的牛群体来改善牛种群的遗传学; 并诊断牛受试者的健康状况。 还公开了通过使用本文鉴定的相关SNP来鉴定与性状相关的另外的SNP的方法。

公开(公告)号：US20110287972A1

公开(公告)日：2011-11-24

申请号：US13192746

申请日：2011-07-28

申请人： Sue DeNise ,  David Rosenfeld ,  Richard Kerr ,  Stephen Bates ,  Tom Holm

发明人： Sue DeNise ,  David Rosenfeld ,  Richard Kerr ,  Stephen Bates ,  Tom Holm

IPC分类号： C40B30/04 ,  C12Q1/68

CPC分类号： C12Q1/6827

摘要： Methods and systems are provided for managing non-beef livestock subjects in order to maximize their individual potential performance and the value of a product from the non-beef livestock subjects, and to maximize profits obtained in marketing the non-beef livestock subjects. The methods and systems draw an inference of a trait of a non-beef livestock subject by determining the nucleotide occurrence of at least one non-beef livestock SNP that is determined to be associated with the trait. The inference is used in methods of the present invention to establish the economic value of a non-beef livestock subject, to improve profits related to selling beef from a non-beef livestock subject; to manage non-beef livestock subjects, to sort non-beef livestock subjects; to improve the genetics of a non-beef livestock population by selecting and breeding of non-beef livestock subjects, to clone a non-beef livestock subject with a specific trait, to track meat or another commercial product of a non-beef livestock subject; and to diagnose a health condition of a non-beef livestock subject. Certain embodiments of the present invention provide methods, systems, and kits are directed to inferences of a trait related to milk or a dairy product in a livestock subject.

摘要翻译： 提供方法和系统，用于管理非牛肉牲畜，以最大限度地发挥其非牛肉牲畜品种的潜在性能和价值，并最大限度地利用非牛肉牲畜品种营销所获得的利润。 方法和系统通过确定确定与性状相关联的至少一种非牛肉牲畜SNP的核苷酸发生来推断非牛肉家畜受试者的性状。 本发明的方法用于确定非牛肉主体的经济价值，提高从非牛肉牲畜中销售牛肉的利润; 管理非牛肉牲畜，对非牛肉牲畜进行分类; 通过选择和培育非牛类牲畜，通过选择具有特殊性状的非牛肉牲畜来追踪非牛肉牲畜的肉类或其他商品，改善非牛类牲畜群体的遗传学; 并诊断非牛肉牲畜的健康状况。 提供方法，系统和试剂盒的本发明的某些实施方案涉及与家畜受试者中的牛奶或乳制品相关的性状的推论。