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公开(公告)号：US4789547A
公开(公告)日：1988-12-06
申请号：US063204
申请日：1987-06-17
CPC分类号： A61K9/7084 , A61K47/32 , A61K47/38 , A61K9/0014
摘要： A composition for the transmembranal, including transdermal, administration of a pharmaceutical preparation comprising cross-linked carboxymethylcellulose, an alcohol soluble poly (2-hydroxyethyl) methacrylate), a permeation enhancer, such as a mixture of linoleic acid and propylene glycol, and a biologically active material, as well as a device for administering the aforementioned composition to mammals, and also a method for administering transdermally to a mammal an effective amount of the aforementioned composition.
摘要翻译： 用于跨膜的组合物，包括经皮，施用包含交联的羧甲基纤维素，醇可溶性聚（2-羟乙基）甲基丙烯酸酯）的药物制剂，渗透促进剂，例如亚油酸和丙二醇的混合物，以及生物学 活性物质，以及用于向哺乳动物施用前述组合物的装置，以及向哺乳动物经皮施用有效量的上述组合物的方法。
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公开(公告)号：US4814173A
公开(公告)日：1989-03-21
申请号：US93850
申请日：1987-09-08
CPC分类号： A61K9/7069 , A61K47/34
摘要： A composition for the transmembranal, including transdermal administration of a pharmaceutical preparation comprising medical grade dimethylsiloxane, a catalyst capable of forming an elastomer, a permeation enhancer and a biologically active material, as well as a device for administering the aforementioned compositions and also a method for administering transdermally to a mammal an effective amount of the aforementioned compositions is herein described.
摘要翻译： 用于跨膜的组合物，包括透皮给药包含医用二甲基硅氧烷的药物制剂，能够形成弹性体的催化剂，渗透促进剂和生物活性物质，以及用于给予上述组合物的装置，以及用于 本文描述了向哺乳动物经皮给药有效量的上述组合物。
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3.发明授权Methylene pyrrolidone copolymers for contact lens and pharmaceutical preparations 失效用于隐形眼镜和药物制剂的亚甲基吡咯烷酮共聚物
公开(公告)号：US5035884A
公开(公告)日：1991-07-30
申请号：US480431
申请日：1990-02-15
CPC分类号： A61K9/7053 , A61K9/284 , A61K9/2846 , A61K9/7061 , A61L15/24 , C07D207/38 , C08F26/06 , G02B1/043
摘要： A new series of copolymers which are useful as coatings for solid dosage forms, for transdermal devices, for wound dressing materials, and for contact lenses. Also disclosed are methods for preparing monomers and polymers as well as pharmaceutical compositions containing such polymers.
摘要翻译： 可用作固体剂型涂层，透皮装置，伤口敷料材料和隐形眼镜的新系列共聚物。 还公开了制备单体和聚合物的方法以及含有这种聚合物的药物组合物。
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公开(公告)号：US4851545A
公开(公告)日：1989-07-25
申请号：US57467
申请日：1987-06-02
CPC分类号： C08F26/06 , A61K9/284 , A61K9/2846 , A61K9/7023 , A61L15/24 , C07D207/38 , G02B1/043
摘要： A new series of copolymers such as N-isopropyl-3-methylene-2-pyrrolidone and 2-hydroxyethylmethacrylate which are useful as coatings for solid dosage forms, for transdermal devices, for wound dressing materials, and for contact lenses. Also disclosed are methods for preparing monomers and polymers as well as pharmaceutical compositions containing such polymers.
摘要翻译： 新的一系列共聚物，如N-异丙基-3-亚甲基-2-吡咯烷酮和甲基丙烯酸2-羟基乙酯，可用作固体剂型的涂层，用于透皮装置，伤口敷料材料和隐形眼镜。 还公开了制备单体和聚合物的方法以及含有这种聚合物的药物组合物。
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公开(公告)号：US4931519A
公开(公告)日：1990-06-05
申请号：US347630
申请日：1989-05-05
CPC分类号： C08F26/06 , A61K9/284 , A61K9/2846 , A61K9/7023 , A61L15/24 , C07D207/38 , G02B1/043
摘要： A new series of copolymers which are useful as coatings for solid dosage forms, for transdermal devices, for wound dressing materials, and for contact lenses. Also disclosed are methods for preparing monomers and polymers as well as pharmaceutical compositions containing such polymers.
摘要翻译： 可用作固体剂型涂层，透皮装置，伤口敷料材料和隐形眼镜的新系列共聚物。 还公开了制备单体和聚合物的方法以及含有这种聚合物的药物组合物。
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6.发明授权Soluble calcium lactate antibacterial complexes as non-irritating parenteral forms 失效可溶性乳酸钙抗菌复合物作为非刺激性胃肠外形式
公开(公告)号：US5290794A
公开(公告)日：1994-03-01
申请号：US966998
申请日：1992-10-27
IPC分类号： C07D401/04 , A61K31/435 , A61K31/44 , A61K31/47 , A61P31/04 , C07D471/04
摘要： Calcium lactate antibacterial complexes in parenteral dosage forms are provided that are relatively free from tissue irritation following injection, comprising a quinolone or naphthyridine.
摘要翻译： 提供了肠胃外剂型中的乳酸乳杆菌抗菌复合物，其在注射后相对不含组织刺激，其包含喹诺酮或萘啶。
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