Plasma display panel
    2.
    发明申请
    Plasma display panel 审中-公开
    等离子显示面板

    公开(公告)号:US20070120487A1

    公开(公告)日:2007-05-31

    申请号:US11604810

    申请日:2006-11-28

    申请人: Sang Ha

    发明人: Sang Ha

    IPC分类号: H01J17/49

    摘要: A plasma display panel is disclosed. The plasma display panel includes a lower substrate including an alignment mark, and a dielectric layer positioned on an area where the alignment mark is excluded from an area of the lower substrate. The dielectric layer contains CuO.

    摘要翻译: 公开了一种等离子体显示面板。 等离子体显示面板包括具有对准标记的下基板和位于从下基板的区域排除对准标记的区域的电介质层。 电介质层含有CuO。

    GENES OF IL-12p40 SUBUNIT MUTATED FOR IMPROVING THE ACTIVITY OF IL-12 AND USE THEREOF FOR DNA VACCINE ADJUVANT
    3.
    发明申请
    GENES OF IL-12p40 SUBUNIT MUTATED FOR IMPROVING THE ACTIVITY OF IL-12 AND USE THEREOF FOR DNA VACCINE ADJUVANT 有权
    用于改善IL-12活性的IL-12p40亚基基因及其用于DNA疫苗补充剂的用途

    公开(公告)号:US20070269408A1

    公开(公告)日:2007-11-22

    申请号:US11832993

    申请日:2007-08-02

    摘要: The present invention relates to the IL-12p40 subunit mutant gene which can produce IL-12 (interleukin 12) of human and mouse origin with high activity, the expression vector including above mutant gene and the use of them to DNA vaccine adjuvant. Particularly, it relates to IL-12p40 mutant gene which inhibits the secretion of IL-12p40 but normally secretes active IL-12p70 by making mutation at Asn-222 (human) or Asn-220 (mouse) amino acid of IL-12p40, which acts as a competitive inhibitor of active form of IL-12, IL-12p70. Therefore, the IL-12p40 mutant gene of the present invention can be useful for DNA vaccination and gene therapy against various diseases, for example, AIDS, hepatitis C or hepatitis B, cancer, influenza, tuberculosis and malaria, which essentially require cellular immune responses for their therapy.

    摘要翻译: 本发明涉及能够产生具有高活性的人和小鼠来源的IL-12(白细胞介素12)的IL-12p40亚基突变基因,包括上述突变基因的表达载体及其用于DNA疫苗佐剂。 特别涉及抑制IL-12p40分泌的IL-12p40突变基因,但通常在IL-12p40的Asn-222(人)或Asn-220(小鼠))氨基酸上突变而分泌活性IL-12p70, 作为IL-12,IL-12p70活性形式的竞争性抑制剂。 因此,本发明的IL-12p40突变基因可用于针对各种疾病(例如艾滋病,丙型肝炎或乙型肝炎,癌症,流感,结核病和疟疾)的DNA疫苗接种和基因治疗,其基本上需要细胞免疫应答 为他们的治疗。