公开(公告)号：US20030129130A1

公开(公告)日：2003-07-10

申请号：US10261110

申请日：2002-09-30

Applicant: SurModics, Inc.

Inventor： Patrick E. Guire ,  Kristin S. Taton ,  John V. Wall

IPC: A61K051/00 ,  A61K049/00 ,  A61K009/14

CPC classification number: B82Y5/00 ,  A61K9/1647 ,  A61K9/1652 ,  A61K9/2081 ,  A61K9/5073 ,  A61K9/5078 ,  A61K47/6927 ,  A61K47/6957 ,  A61K49/0002 ,  A61K49/1821 ,  A61K51/1244 ,  A61L27/54 ,  A61L29/18 ,  A61L31/18 ,  A61L2300/44 ,  A61L2300/604 ,  A61L2300/606 ,  A61L2300/622

Abstract: Surface coatings including microparticles immobilized in a matrix of polymeric material on a substrate are described. The microparticles can also include an agent which can be useful for various applications, such as medical applications. This invention relates to the field of surface coatings for use in various applications. More particularly, the invention relates to surface coating useful for drug delivery, imaging and other uses of microparticles immobilized via a polymeric matrix.

Abstract translation: 描述包括固定在基底上的聚合物材料基质中的微粒的表面涂层。 微粒还可以包括可用于各种应用例如医疗应用的试剂。 本发明涉及用于各种应用的表面涂层领域。 更具体地说，本发明涉及可用于通过聚合物基质固定的微粒的药物递送，成像和其它用途的表面涂层。

公开(公告)号：US20030099949A1

公开(公告)日：2003-05-29

申请号：US09972116

申请日：2001-10-05

Applicant: Surmodics, Inc.

Inventor： Patrick E. Guire ,  Kristin S. Taton

IPC: C12Q001/68 ,  G01N033/53 ,  G01N033/542 ,  B05D003/00

CPC classification number: B01J19/0046 ,  B01J2219/00378 ,  B01J2219/00382 ,  B01J2219/00385 ,  B01J2219/00466 ,  B01J2219/005 ,  B01J2219/00641 ,  B01J2219/00644 ,  B01J2219/00648 ,  B01J2219/00659 ,  C40B60/14

Abstract: Arrays including microparticles having probe moieties are used for the detection of a target in a sample. Microparticles are immobilized in clustered arrangements on at least a portion of a substrate. A detection scheme is performed to detect a marker associated with the target which can be bound to a probe of a clustered arrangement.

Abstract translation: 包括具有探针部分的微粒的阵列用于检测样品中的靶。 微粒在基底的至少一部分上以聚集的方式被固定。 执行检测方案以检测与可以绑定到聚类布置的探针的目标相关联的标记。

公开(公告)号：US20030073086A1

公开(公告)日：2003-04-17

申请号：US09972687

申请日：2001-10-05

Applicant: Surmodics, Inc.

Inventor： Patrick E. Guire ,  Kristin S. Taton ,  John V. Wall

IPC: C12Q001/68 ,  G01N033/53 ,  G01N033/542 ,  B05D003/00 ,  C12M001/34

CPC classification number: B82Y30/00 ,  B01J19/0046 ,  B01J2219/00466 ,  B01J2219/005 ,  B01J2219/00576 ,  B01J2219/00585 ,  B01J2219/0061 ,  B01J2219/00612 ,  B01J2219/00619 ,  B01J2219/00637 ,  B01J2219/00648 ,  B01J2219/00659 ,  B01J2219/00725 ,  B82Y5/00 ,  B82Y10/00 ,  C12Q1/6837 ,  G01N33/54366 ,  Y10S530/81 ,  Y10S530/811 ,  Y10S530/815 ,  Y10S530/816 ,  C12Q2563/149

Abstract: Arrays including microparticles having probe and marker moieties are used for the detection of a target in a sample. Microparticles are randomly immobilized on at least a portion of a substrate. A detection scheme is performed to detect the marker associated with the microparticle and the identity of the probe, and any target bound to the probe.

Abstract translation: 包括具有探针和标记物部分的微粒的阵列用于检测样品中的靶。 微粒随机固定在底物的至少一部分上。 执行检测方案以检测与微粒相关的标记和探针的身份以及与探针结合的任何靶标。