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1.发明授权Plant test procedure to detect natural, semi-synthetic, synthetic compounds and physical stress factors through expression of distinct responses 失效通过表达不同反应来检测天然，半合成，合成化合物和物理应激因子的植物测试程序公开(公告)号：US07262003B2
公开(公告)日：2007-08-28
申请号：US10319111
申请日：2002-12-13
申请人： Sushil Kumar , Suman Preet Singh Khanuja , Mahendra Pandurang Darokar , Tiruppadiripuliyur Ranganathan Santha Kumar , Anita Gangwar , Ajit Kumar Shasany , Srilekha Mishra , Shalini Mathur , Dharmendra Saikia
发明人： Sushil Kumar , Suman Preet Singh Khanuja , Mahendra Pandurang Darokar , Tiruppadiripuliyur Ranganathan Santha Kumar , Anita Gangwar , Ajit Kumar Shasany , Srilekha Mishra , Shalini Mathur , Dharmendra Saikia
IPC分类号： C12Q1/00
摘要： The present invention relates to a method of testing Bacopa monnieri response to abiotic stress factors and for testing bioactivity of natural, synthetic and semisynthetic compounds using Bacopa monnieri plant, which comprises growing the said plant and plant parts aseptically in MS 0 basal medium with agar in microcentrifuge tubes by adding the compounds to be tested either to the culture media or by spraying the said compounds on the plant or plant parts or on the said medium to detect the distinct morphological and cytological responses.
摘要翻译： 本发明涉及使用Bacopa monnieri植物测试对非生物胁迫因子的Bacopa monnieri反应和测试天然，合成和半合成化合物的生物活性的方法，其包括在MS 0基础培养基中无菌地生长所述植物和植物部分，其中琼脂 通过将待测试的化合物加入到培养基中或通过将所述化合物喷洒在植物或植物部分上或所述培养基上以检测不同的形态学和细胞学反应的微量离心管。
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公开(公告)号：US06423541B1
公开(公告)日：2002-07-23
申请号：US09531768
申请日：2000-03-21
申请人： Suman Preet Singh Khanuja , Ajit Kumar Shasany , Sunita Dhawan , Mahendra Pandurang Darokar , Tiruppadiripuliyur Ranganathan Santha Kumar , Dharmendra Saikia , Arif Ali Naqui , Sushil Kumar
发明人： Suman Preet Singh Khanuja , Ajit Kumar Shasany , Sunita Dhawan , Mahendra Pandurang Darokar , Tiruppadiripuliyur Ranganathan Santha Kumar , Dharmendra Saikia , Arif Ali Naqui , Sushil Kumar
IPC分类号： C12N500
摘要： The invention provides a rapid in vitro method for selection of menthol rich mint genotypes from a large population of independent clones, said method comprising the steps of (i) raising a heterogeneous population of Mentha arvensis clones in vitro or by vegetative methods, (ii) transferring the plantlets/shoots to a basal medium, containing cytotoxic compounds in an amount sufficient to cause toxic effect in more than 95% of the clones, (iii) selecting surviving clones, their hardening in the glasshouse, transfer to field, reconfirmation of menthol tolerance through repeated in vitro assays, and (iv) multiplying selected clones and confirming genetic uniformity through RAPD analysis.
摘要翻译： 本发明提供了一种用于从大量独立克隆中选择富含薄荷醇的薄荷基因型的快速体外方法，所述方法包括以下步骤：（i）在体外或通过营养方法提高薄荷亚种克隆的异质群体，（ii） 将小植株/芽转移到基础培养基中，其含有足以在超过95％的克隆中引起毒性作用的细胞毒性化合物，（iii）选择存活的克隆，其在温室中的硬化，转移到野外，再次确认薄荷醇 通过重复体外测定的耐受性，以及（iv）通过RAPD分析来扩增选定的克隆并证实遗传均一性。
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3.发明授权Method for the use of alpha arteether as an anti-bacterial and anti-fungal agent 有权使用αarteether作为抗菌和抗真菌剂的方法
公开(公告)号：US6127405A
公开(公告)日：2000-10-03
申请号：US179204
申请日：1998-10-27
申请人： Sushil Kumar , Suman Preet Singh Khanuja , Tiruppadiripuliyur Ranganathan Santha Kumar , Dharam Chand Jain , Suchi Srivastava , Asish Kumar Bhattacharya , Dharmendra Saikia , Ajit Kumar Shasany , Mahendra Pandurang Darokar , Ram Prakash Sharma
发明人： Sushil Kumar , Suman Preet Singh Khanuja , Tiruppadiripuliyur Ranganathan Santha Kumar , Dharam Chand Jain , Suchi Srivastava , Asish Kumar Bhattacharya , Dharmendra Saikia , Ajit Kumar Shasany , Mahendra Pandurang Darokar , Ram Prakash Sharma
IPC分类号： A61K31/352 , A61K31/335
CPC分类号： A61K31/352
摘要： The present invention relates to use .alpha.-arteether as a antibacterial agent, preferably for gyr mutant bacteria which are resistant to quinolone drugs and can be used as therapeutic agents for treating drug resistant bacterial infections, and also as a antifungal agent.
摘要翻译： 本发明涉及使用α-arteether作为抗菌剂，优选用于对喹诺酮药物具有抗性的gyr突变体细菌，并且可用作治疗药物抗性细菌感染的治疗剂，并且还可用作抗真菌剂。
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公开(公告)号：US07262004B1
公开(公告)日：2007-08-28
申请号：US09487405
申请日：2000-01-18
申请人： Suman Preet Singh Khanuja , Ajit Kumar Shasany , Sunita Dhawan , Mahendra Pandurang Darokar , Sarita Satapathy , Tiruppadiripuliyur Ranganathan Santha Kumar , Dharmendra Saikia , Nirmal Kumar Patra , Janak Raj Bahl , Arun Kumar Tripathy , Sushil Kumar
发明人： Suman Preet Singh Khanuja , Ajit Kumar Shasany , Sunita Dhawan , Mahendra Pandurang Darokar , Sarita Satapathy , Tiruppadiripuliyur Ranganathan Santha Kumar , Dharmendra Saikia , Nirmal Kumar Patra , Janak Raj Bahl , Arun Kumar Tripathy , Sushil Kumar
IPC分类号： C12Q1/68
摘要： An in vitro screening method for identifying insect tolerant genotypes or clones is described. The method comprises growing plantlets in an in vitro system, screening the plantlets for molecular variation of somaclones using RAPD analysis in vitro, selecting the somaclones having molecular variation, exposing the somaclones to insect larvae or nymphs and identifying the surviving somaclones.
摘要翻译： 描述了用于鉴定耐受性基因型或克隆的体外筛选方法。 该方法包括在体外系统中种植小植株，在体外使用RAPD分析来筛选小鼠的分子变异的小植株，选择具有分子变异性的体细胞，将宿体菌暴露于昆虫幼虫或若虫并鉴定存活的体细胞。
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公开(公告)号：USPP14538P2
公开(公告)日：2004-02-17
申请号：US09482645
申请日：2000-01-18
申请人： Suman Preet Singh Khanuja , Ajit Kumar Shasany , Sunita Dhawan , Mahendra Pandurang Darokar , Sarita Satapathy , Tiruppadiripuliyur Ranganathan Santha Kumar , Dharmendra Saikia , Nirmal Kumar Patra , Janak Raj Bahl , Arun Kumar Tripathy , Sushil Kumar
发明人： Suman Preet Singh Khanuja , Ajit Kumar Shasany , Sunita Dhawan , Mahendra Pandurang Darokar , Sarita Satapathy , Tiruppadiripuliyur Ranganathan Santha Kumar , Dharmendra Saikia , Nirmal Kumar Patra , Janak Raj Bahl , Arun Kumar Tripathy , Sushil Kumar
IPC分类号： A01H500
CPC分类号： A01H5/02
摘要： The present invention relates to a novel, insect tolerant, high yielding essential oil and menthol yielding mint plant named ‘Sambhav’, which is a cultivar of Mentha arvensis L.. The mint plant of the present invention has been developed as a result of planned experiments which devised a procedure for early selection of somaclonal variants at the in vitro stage of the variety of Mentha arvensis.
摘要翻译： 本发明涉及一种新颖的耐昆虫高产精油和薄荷醇，产生名为“Sambhav”的薄荷植物，它是薄荷茶的品种。本发明的薄荷植物是由计划的结果而开发的 在Mentha arvensis的体外阶段设计了用于早期选择体细胞克隆变体的程序的实验。
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公开(公告)号：US06423741B1
公开(公告)日：2002-07-23
申请号：US09538439
申请日：2000-03-29
申请人： Suman Preet Singh Khanuja , Suchi Srivastava , Tiruppadiripuliyur Ranganathan Santha Kumar , Ajit Kumar Shasany , Dharam Chand Jain , Mahendra Pandurang Darokar , Dharmendra Saikia , Sushil Kumar
发明人： Suman Preet Singh Khanuja , Suchi Srivastava , Tiruppadiripuliyur Ranganathan Santha Kumar , Ajit Kumar Shasany , Dharam Chand Jain , Mahendra Pandurang Darokar , Dharmendra Saikia , Sushil Kumar
IPC分类号： A61K31335
CPC分类号： A61K31/352
摘要： This invention is related to the development of strategic and novel composition comprising &agr; arteether and nalidixic acid or quinolone drugs, said composition useful as an advanced generation drug to counter the resistance development itself and having a potential to be used in treating infectious diseases and in inhibiting the resistance developed due to mutation in the gyr A gene of bacteria, particularly in those cases where drug resistant strains are known to appear very frequently.
摘要翻译： 本发明涉及包含α-萜烯和萘啶酸或喹诺酮类药物的战略和新型组合物的发展，所述组合物可用作抗逆转发展本身并具有用于治疗感染性疾病和抑制作用的潜力 由于细菌的gyr A基因突变而产生的抗性，特别是在已知耐药菌株出现频繁的情况下。
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7.发明授权公开(公告)号：US06420174B1
公开(公告)日：2002-07-16
申请号：US09536379
申请日：2000-03-28
申请人： Suman Preet Singh Khanuja , Ajit Kumar Shasany , Sunita Dhawan , Mahendra Pandurang Darokar , Tiruppadiripuliyur Ranganathan Santha Kumar , Dharmendra Saikia , Sushil Kumar
发明人： Suman Preet Singh Khanuja , Ajit Kumar Shasany , Sunita Dhawan , Mahendra Pandurang Darokar , Tiruppadiripuliyur Ranganathan Santha Kumar , Dharmendra Saikia , Sushil Kumar
IPC分类号： C12N500
摘要： The present invention is related to a method of producing organogenetic tissues from a plant of the genus Mentha, said method comprising the steps of culturing an explant from a plant of genus Mentha on an initiation medium in the presence of 400 to 600 lux light at a temperature of 23-27° C., with 16 hours of photoperiod, to obtain calli, transferring the calli to a basal medium comprising minerals and vitamins to ensure development of shoots, and culturing the shoots in a medium substantially free of growth hormones and containing menthol in a concentration of about 80 &mgr;g ml−1 to ensure root formation.
摘要翻译： 本发明涉及一种从薄荷属植物生产有机发育组织的方法，所述方法包括以下步骤：在400至600勒克斯光的存在下，在起始培养基上培养来自芒特属植物的外植体， 温度为23-27℃，光周期为16小时，以获得愈伤组织，将愈伤组织转移到包含矿物质和维生素的基础培养基中，以确保芽的发育，并在基本上不含生长激素的培养基中培养芽，并含有 浓缩约80毫升ml-1的薄荷醇以确保根形成。
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8.发明授权公开(公告)号：US06660761B2
公开(公告)日：2003-12-09
申请号：US10066802
申请日：2002-02-06
申请人： Suman Preet Singh Khanuja , Puspalata Chatruvedi , Krishna Kumar Agarwal , Atique Ahmad , Tiruppadiripuliyur Ranganathan Santha Kumar , Mahendra Pandurang Darokar , Ajit Kumar Shasany , Jai Shankar Arya , Sushil Kumar
发明人： Suman Preet Singh Khanuja , Puspalata Chatruvedi , Krishna Kumar Agarwal , Atique Ahmad , Tiruppadiripuliyur Ranganathan Santha Kumar , Mahendra Pandurang Darokar , Ajit Kumar Shasany , Jai Shankar Arya , Sushil Kumar
IPC分类号： A61K314174
CPC分类号： A61K45/06 , A61K31/045 , A61K31/05 , A61K31/22 , A61K31/222 , A61K31/4174 , A61K31/4196 , A61K31/7048 , A61K2300/00
摘要： The present invention relates to a method of treatment of fungal infections consisting essentially of a synergistic combination of plant compounds that are useful for enhancing the activity of antifungal compounds. The plant compounds, menthol and menthyl acetate, when mixed at specific concentrations, enhance the antifungal activity of the commercially available fungicides.
摘要翻译： 本发明涉及一种治疗真菌感染的方法，其基本上由可用于增强抗真菌化合物活性的植物化合物的协同组合组成。 当以特定浓度混合时，植物化合物，薄荷醇和乙酸薄荷酯增强市售杀真菌剂的抗真菌活性。
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公开(公告)号：US06455079B1
公开(公告)日：2002-09-24
申请号：US09923586
申请日：2001-08-07
申请人： Suman Preet Singh Khanuja , Sarita Satapathy , Subhash Chandra Singh , Tiruppadiripuliyur Ranganathan Santha Kumar , Jai Shankar Arya , Arun Kumar Tripathy , Ajit Kumar Shasany , Mahendra Pandurang Darokar , Sushil Kumar
发明人： Suman Preet Singh Khanuja , Sarita Satapathy , Subhash Chandra Singh , Tiruppadiripuliyur Ranganathan Santha Kumar , Jai Shankar Arya , Arun Kumar Tripathy , Ajit Kumar Shasany , Mahendra Pandurang Darokar , Sushil Kumar
IPC分类号： A61K3538
CPC分类号： A01N65/20 , A01N65/00 , A01N2300/00 , A01N63/00 , A01N63/02
摘要： The present invention provides a novel synergistic composition comprising extract obtained from the plant Albizzia lebbeck together with Bacillus thuringiensis &dgr;-endotoxin, useful in controlling lepidopteran insects, methods for the preparation of the composition and application of the insecticidal composition to standing crops.
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公开(公告)号：US06831100B2
公开(公告)日：2004-12-14
申请号：US10462646
申请日：2003-06-17
申请人： Suman Preet Singh Khanuja , Krishna Kumar Agarwal , Tiruppadiripuliyur Ranganathan Santha Kumar , Atique Ahmad , Ajit Kumar Shasany , Mahendra Pandurang Darokar , Sushil Kumar
发明人： Suman Preet Singh Khanuja , Krishna Kumar Agarwal , Tiruppadiripuliyur Ranganathan Santha Kumar , Atique Ahmad , Ajit Kumar Shasany , Mahendra Pandurang Darokar , Sushil Kumar
IPC分类号： A61K3121
摘要： The present invention describes a novel and very quick bacterial system based screening protocol to detect UV protectant molecules and determining their efficacy for the extent of protection against Ultraviolet radiation in biological systems, identifying a new use of the compound menthyl benzoate as efficient UV protectant suitable for providing protection against the harmful effects of ultraviolet radiation and the extent of protection provided by menthyl benzoate.
摘要翻译： 本发明描述了一种新颖且非常快速的基于细菌系统的筛选方案，用于检测UV保护剂分子并确定其在生物系统中对紫外线辐射的保护程度的功效，鉴定了复合苯甲酸薄荷酯的新用途，作为适合于 提供防止紫外线辐射的有害影响和苯甲酸薄荷酯提供的保护程度。
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