公开(公告)号：US09750748B2

公开(公告)日：2017-09-05

申请号：US14652484

申请日：2013-12-17

Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED

Inventor： William Farnaby ,  Charlotte Fieldhouse ,  Katherine Hazel ,  Catrina Kerr ,  Natasha Kinsella ,  David Livermore ,  Kevin Merchant ,  David Miller

IPC: A61K31/55 ,  C07D405/04 ,  A61K31/501 ,  C07D403/04 ,  C07D237/20 ,  C07D401/04 ,  A61K45/06 ,  A61K31/50 ,  C07D237/16 ,  C07D237/22 ,  A61K31/277 ,  A61K31/496 ,  A61K31/519 ,  A61K31/53 ,  A61K31/551 ,  A61K31/554 ,  A61K33/00

CPC classification number: A61K31/55 ,  A61K31/277 ,  A61K31/496 ,  A61K31/50 ,  A61K31/501 ,  A61K31/519 ,  A61K31/53 ,  A61K31/551 ,  A61K31/554 ,  A61K33/00 ,  A61K45/06 ,  C07D237/16 ,  C07D237/20 ,  C07D237/22 ,  C07D401/04 ,  C07D403/04 ,  C07D405/04 ,  A61K2300/00

Abstract: The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein R1 and R2 are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.