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公开(公告)号：US20210347786A1
公开(公告)日：2021-11-11
申请号：US17280634
申请日：2019-09-27
发明人： Shinobu SASAKI , Yasutomi ASANO , Hironobu MAEZAKI , Ayumu SATO
IPC分类号： C07D498/04 , A61P1/00
摘要： The present invention aims to provide a compound that may be useful for the prophylaxis or treatment of constipation and the like. The present invention provides a compound represented by the formula (I): wherein each symbol is as described in the specification, or a salt thereof.
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公开(公告)号：US20210139491A1
公开(公告)日：2021-05-13
申请号：US16622632
申请日：2018-06-19
发明人： Kazuaki TAKAMI , Masaki SETO , Shinobu SASAKI , Haruhi ANDO , Masaki OGINO , Tomoko OHASHI , Toshihiro IMAEDA , Ikuo FUJIMORI , Yasuhiro TSUKIMI , Masami YAMADA , Kenichiro SHIMOKAWA , Takeshi WAKABAYASHI , Masataka MURAKAMI , Makoto FUSHIMI , Tomohiro OKAWA , Jinichi YONEMORI , Tomohiro OHASHI , Hideo SUZUKI , Hironobu MAEZAKI , Ayumu SATO , Yasutomi ASANO , Steve SWANN
IPC分类号： C07D491/048 , A61K31/4355 , A61P1/10
摘要： The present invention aims to provide a compound that may be useful for the prophylaxis or treatment of constipation and the like. The present invention provides a compound represented by the following formula (I): wherein each symbol is as described in the specification, or a salt thereof.
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公开(公告)号：US20230303541A1
公开(公告)日：2023-09-28
申请号：US18081395
申请日：2022-12-14
发明人： Shinobu SASAKI , Masaki SETO , Kazuaki TAKAMI , Haruhi ANDO
IPC分类号： C07D405/14 , C07D405/04 , C07D409/14 , A61P1/10
CPC分类号： C07D405/14 , A61P1/10 , C07D405/04 , C07D409/14
摘要： The present invention aims to provide a compound that may be useful for the prophylaxis or treatment of constipation and the like. The present invention provides a compound represented by the following formula (I):
wherein each symbol is as described in the specification, or a salt thereof.-
公开(公告)号：US20210380565A1
公开(公告)日：2021-12-09
申请号：US17280633
申请日：2019-09-27
发明人： Shinobu SASAKI , Yasutomi ASANO , Kazuaki TAKAMI , Masaki SETO , Haruhi ANDO
IPC分类号： C07D405/14 , A61P1/10 , C07D407/12 , C07D413/14 , C07D417/14 , C07D407/14
摘要： The present invention aims to provide a compound that may be useful for the prophylaxis or treatment of constipation and the like. The present invention provides a compound represented by the formula (I): wherein R1 is a hydrogen atom, a halogen atom, an optionally substituted C1-6 alkyl group, or an optionally substituted C1-6 alkoxy group; and ring A is an optionally further substituted ring, or a salt thereof.
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公开(公告)号：US20210292308A1
公开(公告)日：2021-09-23
申请号：US16606043
申请日：2018-04-17
发明人： Shinobu SASAKI , Masaki SETO , Kazuaki TAKAMI , Haruhi ANDO
IPC分类号： C07D405/14 , C07D405/04 , C07D409/14 , A61P1/10
摘要： The present invention aims to provide a compound that may be useful for the prophylaxis or treatment of constipation and the like. The present invention provides a compound represented by the following formula (I): wherein each symbol is as described in the specification, salt thereof.
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公开(公告)号：US20190135799A1
公开(公告)日：2019-05-09
申请号：US16049359
申请日：2018-07-30
发明人： Masahiro ITO , Hideyuki SUGIYAMA , Osamu KUBO , Fumiaki KIKUCHI , Takeshi YASUI , Keiko KAKEGAWA , Zenichi IKEDA , Tohru MIYAZAKI , Yasuyoshi ARIKAWA , Tomohiro OKAWA , Jinichi YONEMORI , Akinori TOITA , Takuto KOJIMA , Yasutomi ASANO , Ayumu SATO , Hironobu MAEZAKI , Shinobu SASAKI , Hironori KOKUBO , Misaki HOMMA , Minoru SASAKI , Yasuhiro IMAEDA
IPC分类号： C07D413/14 , C07D471/04 , A61P25/28 , C07D413/04 , C07D417/14
CPC分类号： C07D413/14 , A61P25/28 , C07D413/04 , C07D417/14 , C07D471/04 , C07D487/04
摘要： The present invention provides a heterocyclic compound having a HDAC inhibitory action, and useful for the treatment of central nervous system diseases including neurodegenerative disease, and the like, and a medicament comprising the compound.The present invention relates to a compound represented by the formula (I): wherein each symbol is as defined in the specification, or a salt thereof.
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