公开(公告)号：US20230113633A1

公开(公告)日：2023-04-13

申请号：US18081322

申请日：2022-12-14

Applicant: TANAKA KIKINZOKU KOGYO K.K. ,  TOKUSHIMA UNIVERSITY

Inventor： Michimasa OKUBO ,  Kenji GOTO ,  Kunihiro TANAKA ,  Kojiro SHIRAISHI ,  Kunihiro SHIMA ,  Yuya KATO ,  Kenichi HAMADA ,  Eiichi HONDA ,  Emi TAKEGAWA

IPC: C22C5/02 ,  A61L29/02 ,  A61L31/02 ,  C22F1/14

Abstract: The present invention relates to a medical Au-Pt-Pd alloy including Au, Pt,Pd, and inevitable impurities. The Au-Pt-Pd alloy has an alloy compositioninside a polygon (A1-A2-A3-A4) surrounded by straight lines connected at pointA1 (Au: 53 atom%, Pt: 4 atom%, and Pd: 43 atom%), point A2 (Au: 70 atom%,Pt: 4 atom%, and Pd: 26 atom%), point A3 (Au: 69.9 atom%, Pt: 30 atom%, and Pd: 0.1 atom%), and point A4 (Au: 49.9 atom%, Pt: 50 atom%, and Pd: 0.1 atom%) in a Au-Pt-Pd ternary state diagram. In a metal structure of the alloy, at least one of a Au-rich phase and a Pt-rich phase is distributed, and the total of the area ratio of the Au-rich phase and the area ratio of the Pt-rich phase is 1.5% or more and 25.4% or less.

公开(公告)号：US20200225198A1

公开(公告)日：2020-07-16

申请号：US16081984

申请日：2017-03-03

Applicant: TANAKA KIKINZOKU KOGYO K.K.

Inventor： Keita SUZUKI ,  Yuya KATO ,  Hisahiko IWAMOTO

IPC: B01J20/281 ,  G01N33/543 ,  G01N33/569

Abstract: The invention relates to an immunochromatographic device which contains a nitrous acid compound and an organic acid or an organic acid derivative and which is for detecting a detection target in an analyte wherein a sample droplet-receiving member, a labeling substance-holding member, a chromatography medium member and an absorption member are arranged in a manner that a sample develops in this order and wherein a part containing the nitrous acid compound and a part containing the organic acid or the like are at upstream positions from the labeling substance-containing part, and the part containing the nitrous acid compound and the part containing the organic acid or the like are not substantially in contact with each other in the thickness direction.

公开(公告)号：US20180209970A1

公开(公告)日：2018-07-26

申请号：US15744501

申请日：2016-07-15

Applicant: TANAKA KIKINZOKU KOGYO K.K.

Inventor： Yuya KATO ,  Hisahiko IWAMOTO

IPC: G01N33/543 ,  G01N33/569

Abstract: The present invention is intended to provide an immunoassay method that enables an immunoassay with high sensitivity at a high development rate without causing aggregation of insoluble carriers or non-specific reaction while improving test efficiency and reducing labor. The present invention relates to an immunoassay method that uses a test device, and the method includes: extracting an antigen of a detection target in an analyte with an extraction agent; and detecting the detection target with a detection reagent capable of binding the antigen. The extraction agent is a nitrous acid generated on the test device by a contact reaction between a nitrite salt and a heterocyclic compound having at least one skeleton selected from the group consisting of a cyclic ester, a cyclic amide, and a cyclic imide.

公开(公告)号：US20220017996A1

公开(公告)日：2022-01-20

申请号：US17295778

申请日：2019-11-18

Applicant: TANAKA KIKINZOKU KOGYO K.K.

Inventor： Shubham YADAV ,  Yuya KATO ,  Kenji GOTO ,  Kunihiro SHIMA

IPC: C22C19/07 ,  A61L31/02

Abstract: The present invention relates to an alloy for medical use, including Pt, Co, Cr, Ni, and Mo. The alloy includes 10 atom % or more and 30 atom % or less of Pt, 20 atom % or more and 31 atom % or less of Cr, 5 atom % or more and 24 atom % or less of Ni, 4 atom % or more and 8 atom % or less of Mo, the balance Co, and unavoidable impurities, and a ratio of the Ni content (CNi) to the Pt content (CPt), CNi/CPt is 1.5 or less. The present invention can be applied to various kinds of devices for medical use, such as catheter, embolic coils, and guide wires, in addition to stents such as flow-diverter stents.

公开(公告)号：US20170023559A1

公开(公告)日：2017-01-26

申请号：US15301651

申请日：2015-03-31

Applicant: TANAKA KIKINZOKU KOGYO K.K.

Inventor： Hisahiko IWAMOTO ,  Kazuyoshi MOCHIDUKI ,  Daisuke ITO ,  Yuya KATO

IPC: G01N33/543 ,  B01D15/10 ,  B01D15/38

CPC classification number: G01N33/54306 ,  B01D15/10 ,  B01D15/3809 ,  B01D15/3857 ,  G01N33/543 ,  G01N33/54386

Abstract: An object is to provide an immunochromatographic analysis method capable of shortening the developing time without decreasing the detection sensitivity, and also capable of reducing the return of the liquid of a developed component, and a method for detecting a detection target contained in an analyte using an immunochromatographic analysis device including an absorption part composed of glass fiber, wherein the analyte and a labeling substance are developed in a chromatography medium part as a mobile phase in the presence of a nonionic surfactant, and the detection target is detected in a detection part is provided.

Abstract translation: 本发明的目的是提供能够缩短显影时间而不降低检测灵敏度的免疫色谱分析方法，并且还能够降低显影组分的液体的返回率，以及用于检测包含在分析物中的检测目标的方法， 包含由玻璃纤维构成的吸收部的免疫色谱分析装置，其特征在于，在非离子表面活性剂的存在下，以分析物和标记物质作为流动相在色谱介质部分中显影，并且在检测部中检测出检测对象物 。

公开(公告)号：US20220213576A1

公开(公告)日：2022-07-07

申请号：US17607397

申请日：2020-09-24

Applicant: TANAKA KIKINZOKU KOGYO K.K. ,  TOKUSHIMA UNIVERSITY

Inventor： Michimasa OKUBO ,  Kenji GOTO ,  Kunihiro TANAKA ,  Kojiro SHIRAISHI ,  Kunihiro SHIMA ,  Yuya KATO ,  Kenichi HAMADA ,  Eiichi HONDA ,  Emi TAKEGAWA

IPC: C22C5/02 ,  C22C1/02

Abstract: The present invention relates to a medical Au—Pt—Pd alloy including Au, Pt, Pd, and inevitable impurities. The alloy has an alloy composition inside a polygon (A1-A2-A3-A4-A5-A6) surrounded by straight lines connected at point A1 (Au: 37.9 atom %, Pt: 0.1 atom %, and Pd: 62 atom %), point A2 (Au: 79.9 atom %, Pt: 0.1 atom %, and Pd: 20 atom %), point A3 (Au: 79.9 atom %, Pt: 20 atom %, and Pd: 0.1 atom %), point A4 (Au: 69.9 atom %, Pt: 30 atom %, and Pd: 0.1 atom %), point A5 (Au: 49 atom %, Pt: 30 atom %, and Pd: 21 atom %), and point A6 (Au: 39 atom %, Pt: 40 atom %, and Pd: 21 atom %) in a Au—Pt—Pd ternary state diagram. The metal structure of the alloy is optimized, and the metal structure is close to a single-phase structure, and has little precipitation of a Au-rich phase and a Pt-rich phase different in composition from a mother phase.

公开(公告)号：US20160370368A1

公开(公告)日：2016-12-22

申请号：US14910295

申请日：2014-08-08

Applicant: TANAKA KIKINZOKU KOGYO K.K.

Inventor： Yuya KATO ,  Hisahiko IWAMOTO

IPC: G01N33/569

CPC classification number: G01N33/56944 ,  G01N33/5306 ,  G01N33/54393 ,  G01N33/558 ,  G01N2400/10 ,  G01N2400/18 ,  G01N2469/10

Abstract: Disclosed herein is an immunoassay method for detecting the detection target antigen in an analyte through extraction with an extraction agent. The method is characterized in that the detection is performed in the presence of a cyclic oligosaccharide. The method is also characterized in the use of an immunochromatography kit for detecting gram-positive bacteria in an analyte, and that is configured from an analyte dilution solution, a sample dropping part, an antigen extracting part, a labeling substance retaining part, an immunochromatography medium having a detection part, and an absorption part, and in which an organic acid is retained in the antigen extracting part. The immunochrornatography kit contains a cyclic oligosaccharide and a nitrite compound by containing at least one of a cyclic oligosaccharide, a nitrite compound, and a mixture thereof in the analyte dilution solution and/or the sample dropping part.

Abstract translation: 本文公开了一种通过用提取剂提取来检测分析物中的检测目标抗原的免疫测定方法。 该方法的特征在于，在环状寡糖的存在下进行检测。 该方法的特征还在于使用免疫色谱试剂盒来检测分析物中的革兰氏阳性细菌，并且由分析物稀释溶液，滴液部分，抗原提取部分，标记物质保留部分，免疫色谱法 具有检测部分的介质和吸收部分，并且其中有机酸保留在抗原提取部分中。 免疫层析试剂盒在分析物稀释溶液和/或样品滴下部分中含有环状低聚糖和亚硝酸盐化合物，其中含有环状低聚糖，亚硝酸盐化合物及其混合物中的至少一种。