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公开(公告)号：US11318112B2
公开(公告)日：2022-05-03
申请号：US15560573
申请日：2016-03-22
发明人： He Sun , Xijun Yan , Naifeng Wu , Kaijing Yan , Yonghong Zhu , Shunnan Zhang , Xiaolin Bai , Xiaohui Ma , Yi He , Ting Li , Lei Li
IPC分类号： A61K31/357 , A61K36/82 , A61K47/24 , A61K9/48 , A61K31/205 , A61P1/16 , A61K9/16 , A61K31/355 , A61K31/683 , A61K9/08 , A61K36/488
摘要： A pharmaceutical composition is prepared from the following raw materials (in parts by weight): silybin (8.75-60), phospholipid (15-65), a Pu'er tea extract (25-200), and vitamin E (6.25-40). The composition has the effect of treating non-alcoholic fatty liver diseases.
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公开(公告)号：US10507197B2
公开(公告)日：2019-12-17
申请号：US15560576
申请日：2016-03-22
发明人： Naifeng Wu , Xijun Yan , He Sun , Kaijing Yan , Yonghong Zhu , Shunnan Zhang , Xiaolin Bai , Yi He , Xiaohui Ma , Ting Li , Lei Li
IPC分类号： A61K31/357 , A61K36/82 , A61K47/24 , A61K9/48 , A61K31/205 , A61P1/16 , A61K9/16 , A61K31/355 , A61K31/683 , A61K9/08 , A61K36/488
摘要： Disclosed is a pharmaceutical composition containing silibinin, which is prepared from the following bulk drugs by weight ratio: 8.75-60 parts of silibinin, 15-65 parts of phospholipid, and 25-200 parts of Pu'er tea extract. The drug has the function of treating non-alcoholic fatty liver.
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公开(公告)号：US10376491B2
公开(公告)日：2019-08-13
申请号：US15560583
申请日：2016-03-22
发明人： Xijun Yan , Naifeng Wu , He Sun , Kaijing Yan , Yonghong Zhu , Xiaohui Ma , Shunnan Zhang , Changwen Li , Xiaolin Bai , Ting Li , Lei Li , Yi He
IPC分类号： A61K36/00 , A61K31/357 , A61K36/82 , A61K47/24 , A61K9/48 , A61K31/205 , A61P1/16 , A61K9/16 , A61K31/355 , A61K31/683 , A61K9/08 , A61K36/488
摘要： Disclosed are a pharmaceutical composition for treating non-alcoholic fatty liver and a method for preparing same. The composition is prepared from the following hulk drugs by weight ratio: 8.75-60 parts of silibinin, 15-65 parts of phospholipid, 25-200 parts of Pu'er tea extract, and 5-50 parts of radix puerariae extract.
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公开(公告)号：US10307396B2
公开(公告)日：2019-06-04
申请号：US15560568
申请日：2016-03-22
发明人： He Sun , Xijun Yan , Naifeng Wu , Kaijing Yan , Yonghong Zhu , Shunnan Zhang , Xiaolin Bai , Xiaohui Ma , Yi He , Ting Li , Lei Li
IPC分类号： A61K31/35 , A61K31/357 , A61K36/82 , A61K47/24 , A61K9/48 , A61K31/205 , A61P1/16 , A61K9/16 , A61K31/355 , A61K31/683 , A61K9/08 , A61K36/488
摘要： A pharmaceutical composition. The pharmaceutical composition is prepared from the following raw materials in parts by weight: 8.75-60 parts of silybin, 15-65 parts of phospholipid, 25-200 parts of a Pu'er tea extract, 6.25-40 parts of vitamin E, and 8.3-60 parts of L-carnitine. The composition can be used for treating non-alcoholic fatty liver diseases.
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公开(公告)号：US10376490B2
公开(公告)日：2019-08-13
申请号：US15560578
申请日：2016-03-22
发明人： Naifeng Wu , Xijun Yan , He Sun , Kaijing Yan , Yonghong Zhu , Shunnan Zhang , Xiaolin Bai , Yi He , Xiaohui Ma , Ting Li
IPC分类号： A61K9/00 , A61K9/14 , A61K9/16 , A61K9/20 , A61K9/48 , A61K36/82 , A61K47/24 , B65D81/32 , A61K31/357
摘要： A pharmaceutical composition for treating non-alcoholic fatty liver diseases consists of a silybin-phospholipid complex preparation and Pu'er tea/tea product according to a weight ratio of 0.5-2.5:0.3-10, wherein the silybin-phospholipid complex capsule preparation and the Pu'er teat/tea product are separately packaged.
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公开(公告)号：US10307395B2
公开(公告)日：2019-06-04
申请号：US15560560
申请日：2016-03-22
发明人： He Sun , Xijun Yan , Naifeng Wu , Kaijing Yan , Yonghong Zhu , Shunnan Zhang , Xiaolin Bai , Xiaohui Ma , Yi He , Ting Li , Lei Li
IPC分类号： A61K36/00 , A61K31/357 , A61K36/82 , A61K47/24 , A61K9/48 , A61K31/205 , A61P1/16 , A61K9/16 , A61K31/355 , A61K31/683 , A61K9/08 , A61K36/488
摘要： A pharmaceutical composition for treating non-alcoholic fatty liver diseases. The pharmaceutical composition is prepared from 8.75-60 parts by weight of silybin, 15-65 parts by weight of phospholipid, 25-150 parts by weight of a Pu'er tea extract, and 10.425-60 parts by weight of L-carnitine.
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公开(公告)号：US11491173B2
公开(公告)日：2022-11-08
申请号：US16976832
申请日：2019-04-04
发明人： Shuiping Zhou , He Sun , Yiqian Zhang , Xiaohui Ma , Jiawen Shi , Yi He , Xinxin Li , Jing Wang , Xiaoqing Li , Lijun Fan , Jingjing Zhang
IPC分类号： A61K31/7048 , A61P9/04 , A61K31/216 , A61K31/343 , A61K31/405 , A61K31/704
摘要： Disclosed are a pharmaceutical composition and an application thereof. The pharmaceutical composition of the present invention comprises the following components in parts by weight: 2-20 parts of phenolic acids, 0.5-5 parts of flavonoids, 0.005-0.5 part of tanshinones, 5-20 parts of saponins, and 10-18 parts of volatile oils. The pharmaceutical composition has the functions of protecting against myocardial damage and treating heart failure.
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公开(公告)号：US12090138B2
公开(公告)日：2024-09-17
申请号：US17588033
申请日：2022-01-28
发明人： He Sun , Xijun Yan , Naifeng Wu , Kaijing Yan , Yonghong Zhu , Shunnan Zhang , Xiaolin Bai , Xiaohui Ma , Yi He , Ting Li , Lei Li
IPC分类号： A61K31/357 , A61K9/08 , A61K9/16 , A61K9/48 , A61K31/205 , A61K31/355 , A61K31/683 , A61K36/488 , A61K36/82 , A61K47/24 , A61P1/16
CPC分类号： A61K31/357 , A61K9/08 , A61K9/1617 , A61K9/1682 , A61K9/48 , A61K31/205 , A61K31/355 , A61K31/683 , A61K36/488 , A61K36/82 , A61K47/24 , A61P1/16 , A61K2236/19
摘要： A pharmaceutical composition is prepared from the following raw materials (in parts by weight): silybin (8.75-60), phospholipid (15-65), a Pu'er tea extract (25-200), and vitamin E (6.25-40). The composition has the effect of treating non-alcoholic fatty liver diseases.
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