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公开(公告)号：US10300030B2
公开(公告)日：2019-05-28
申请号：US14910088
申请日：2014-08-28
发明人： Xijun Yan , Naifeng Wu , Shunnan Zhang , Ping Li , Zhengliang Ye , Lihong Zhou , Lianwen Qi , Fenglian Zhang , Minchao Qi , Zhexuan Yang , Wei Sun , Jing Yu , Hua Yang , Peng Liu , Xiaohui Ma , Hai'ou Dong , Wensheng Zhang , Lanlan Zhang , Chenming Li
IPC分类号： A61K31/192 , A61K31/704 , A61K36/537 , A61K31/7028 , A61K31/11 , A61K31/216 , A61K31/343 , A61K31/352 , A61K36/258
摘要： A traditional Chinese medicine composition and preparation thereof for treating cardiovascular diseases is provided. The traditional Chinese medicine composition consists of: by weight percentage, phenolic acid derivatives 30%˜80%, tanshinones 2%˜10% and saponins 15%˜60%.
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公开(公告)号：US11491173B2
公开(公告)日：2022-11-08
申请号：US16976832
申请日：2019-04-04
发明人： Shuiping Zhou , He Sun , Yiqian Zhang , Xiaohui Ma , Jiawen Shi , Yi He , Xinxin Li , Jing Wang , Xiaoqing Li , Lijun Fan , Jingjing Zhang
IPC分类号： A61K31/7048 , A61P9/04 , A61K31/216 , A61K31/343 , A61K31/405 , A61K31/704
摘要： Disclosed are a pharmaceutical composition and an application thereof. The pharmaceutical composition of the present invention comprises the following components in parts by weight: 2-20 parts of phenolic acids, 0.5-5 parts of flavonoids, 0.005-0.5 part of tanshinones, 5-20 parts of saponins, and 10-18 parts of volatile oils. The pharmaceutical composition has the functions of protecting against myocardial damage and treating heart failure.
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公开(公告)号：US20170224623A1
公开(公告)日：2017-08-10
申请号：US15469711
申请日：2017-03-27
发明人： Henry Sun , Xiaohui Ma , Zhixin Guo , Sen Lin , Genbei Wang , Lulu Yan , Lihua Zhang , Shuiping Zhou , Shunnan Zhang
IPC分类号： A61K9/16 , B01J2/00 , A61K31/365
CPC分类号： A61K9/1682 , A61K9/1635 , A61K9/1676 , A61K9/5026 , A61K9/5078 , A61K31/365 , B01J2/006
摘要： The present invention relates to an andrographolide enteric targeting micropellet and method for preparation thereof; furthermore, the present invention also relates to uses of andrographolide and andrographolide enteric targeting micropellets in the preparation of a pharmaceutical for treatment of inflammatory bowel disease.
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公开(公告)号：US10376490B2
公开(公告)日：2019-08-13
申请号：US15560578
申请日：2016-03-22
发明人： Naifeng Wu , Xijun Yan , He Sun , Kaijing Yan , Yonghong Zhu , Shunnan Zhang , Xiaolin Bai , Yi He , Xiaohui Ma , Ting Li
IPC分类号： A61K9/00 , A61K9/14 , A61K9/16 , A61K9/20 , A61K9/48 , A61K36/82 , A61K47/24 , B65D81/32 , A61K31/357
摘要： A pharmaceutical composition for treating non-alcoholic fatty liver diseases consists of a silybin-phospholipid complex preparation and Pu'er tea/tea product according to a weight ratio of 0.5-2.5:0.3-10, wherein the silybin-phospholipid complex capsule preparation and the Pu'er teat/tea product are separately packaged.
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公开(公告)号：US10307395B2
公开(公告)日：2019-06-04
申请号：US15560560
申请日：2016-03-22
发明人： He Sun , Xijun Yan , Naifeng Wu , Kaijing Yan , Yonghong Zhu , Shunnan Zhang , Xiaolin Bai , Xiaohui Ma , Yi He , Ting Li , Lei Li
IPC分类号： A61K36/00 , A61K31/357 , A61K36/82 , A61K47/24 , A61K9/48 , A61K31/205 , A61P1/16 , A61K9/16 , A61K31/355 , A61K31/683 , A61K9/08 , A61K36/488
摘要： A pharmaceutical composition for treating non-alcoholic fatty liver diseases. The pharmaceutical composition is prepared from 8.75-60 parts by weight of silybin, 15-65 parts by weight of phospholipid, 25-150 parts by weight of a Pu'er tea extract, and 10.425-60 parts by weight of L-carnitine.
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公开(公告)号：US09889093B2
公开(公告)日：2018-02-13
申请号：US14910173
申请日：2014-08-06
发明人： Henry Sun , Xiaohui Ma , Zhixin Guo , Sen Lin , Genbei Wang , Lulu Yan , Lihua Zhang , Shuiping Zhou , Shunnan Zhang
IPC分类号： A61K9/16 , A61K31/365 , A61K9/50 , B01J2/00
CPC分类号： A61K9/1682 , A61K9/1635 , A61K9/1676 , A61K9/5026 , A61K9/5078 , A61K31/365 , B01J2/006
摘要： The present invention relates to an andrographolide enteric targeting micropellet and a method for preparation thereof; furthermore, the present invention also relates to uses of andrographolide and andrographolide enteric targeting micropellets in preparation of a pharmaceutical for treatment of inflammatory bowel disease.
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7.发明申请NEW SALVIANOLIC ACID COMPOUND T, PREPARATION METHOD THEREFOR, AND USE THEREOF 审中-公开新的维生素A化合物T，其制备方法及其用途公开(公告)号：US20160200661A1
公开(公告)日：2016-07-14
申请号：US14914166
申请日：2014-08-26
发明人： Shuiping Zhou , Wei Li , Yuanpeng Jin , Xinxin Li , Xiaohui Ma , Wei Zhou , Min Han , Shuming Li
IPC分类号： C07C69/732 , C07C67/56
CPC分类号： C07C69/732 , A61K36/537 , A61K2236/00 , C07B2200/09 , C07C67/56
摘要： The present invention relates to the medical field, specifically a salvianolic acid T as described in structural formula (I), a chiral isomer thereof, a preparation method therefor, pharmaceutical compositions, antioxidants, and free radical scavengers thereof, and a use of the compound.
摘要翻译： 本发明涉及医学领域，特别是结构式（I）所述的丹酚酸T，其手性异构体，其制备方法，药物组合物，抗氧化剂及其自由基清除剂，以及该化合物 。
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公开(公告)号：US11318112B2
公开(公告)日：2022-05-03
申请号：US15560573
申请日：2016-03-22
发明人： He Sun , Xijun Yan , Naifeng Wu , Kaijing Yan , Yonghong Zhu , Shunnan Zhang , Xiaolin Bai , Xiaohui Ma , Yi He , Ting Li , Lei Li
IPC分类号： A61K31/357 , A61K36/82 , A61K47/24 , A61K9/48 , A61K31/205 , A61P1/16 , A61K9/16 , A61K31/355 , A61K31/683 , A61K9/08 , A61K36/488
摘要： A pharmaceutical composition is prepared from the following raw materials (in parts by weight): silybin (8.75-60), phospholipid (15-65), a Pu'er tea extract (25-200), and vitamin E (6.25-40). The composition has the effect of treating non-alcoholic fatty liver diseases.
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公开(公告)号：US10507197B2
公开(公告)日：2019-12-17
申请号：US15560576
申请日：2016-03-22
发明人： Naifeng Wu , Xijun Yan , He Sun , Kaijing Yan , Yonghong Zhu , Shunnan Zhang , Xiaolin Bai , Yi He , Xiaohui Ma , Ting Li , Lei Li
IPC分类号： A61K31/357 , A61K36/82 , A61K47/24 , A61K9/48 , A61K31/205 , A61P1/16 , A61K9/16 , A61K31/355 , A61K31/683 , A61K9/08 , A61K36/488
摘要： Disclosed is a pharmaceutical composition containing silibinin, which is prepared from the following bulk drugs by weight ratio: 8.75-60 parts of silibinin, 15-65 parts of phospholipid, and 25-200 parts of Pu'er tea extract. The drug has the function of treating non-alcoholic fatty liver.
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公开(公告)号：US10376491B2
公开(公告)日：2019-08-13
申请号：US15560583
申请日：2016-03-22
发明人： Xijun Yan , Naifeng Wu , He Sun , Kaijing Yan , Yonghong Zhu , Xiaohui Ma , Shunnan Zhang , Changwen Li , Xiaolin Bai , Ting Li , Lei Li , Yi He
IPC分类号： A61K36/00 , A61K31/357 , A61K36/82 , A61K47/24 , A61K9/48 , A61K31/205 , A61P1/16 , A61K9/16 , A61K31/355 , A61K31/683 , A61K9/08 , A61K36/488
摘要： Disclosed are a pharmaceutical composition for treating non-alcoholic fatty liver and a method for preparing same. The composition is prepared from the following hulk drugs by weight ratio: 8.75-60 parts of silibinin, 15-65 parts of phospholipid, 25-200 parts of Pu'er tea extract, and 5-50 parts of radix puerariae extract.
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