公开(公告)号：US10690668B2

公开(公告)日：2020-06-23

申请号：US14375263

申请日：2013-01-29

Applicant: TEMPLE UNIVERSITY—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION

Inventor： Kamel Khalili ,  Ilker K. Sariyer

IPC: G01N33/53 ,  G01N33/569

Abstract: The invention provides methods of detection and monitoring of polyomavirus reactivation and active polyomavirus infections using a biological fluid sample. Also provided are methods of risk assessment and risk monitoring of developing a polyomavirus-associated disease.

公开(公告)号：US20150010901A1

公开(公告)日：2015-01-08

申请号：US14375263

申请日：2013-01-29

Applicant: TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION

Inventor： Kamel Khalili ,  Ilker K. Sariyer

IPC: G01N33/569

CPC classification number: G01N33/56983 ,  G01N2333/025 ,  G01N2469/10 ,  G01N2469/20 ,  G01N2800/50 ,  G01N2800/56

Abstract: The invention provides methods of detection and monitoring of polyomavirus reactivation and active polyomavirus infections using a biological fluid sample. Also provided are methods of risk assessment and risk monitoring of developing a polyomavirus-associated disease.

Abstract translation: 本发明提供使用生物流体样品检测和监测多瘤病毒再活化和活性多瘤病毒感染的方法。 还提供了开发多瘤病毒相关疾病的风险评估和风险监测方法。

公开(公告)号：US20240009221A1

公开(公告)日：2024-01-11

申请号：US18300468

申请日：2023-04-14

Applicant: Temple University - of the Commonwealth System of Higher Education

Inventor： Kamel Khalili ,  Shuren Liao ,  Ilker K. Sariyer

IPC: A61K31/706 ,  A61K31/505 ,  A61P31/14

CPC classification number: A61K31/706 ,  A61K31/505 ,  A61P31/14

Abstract: Compositions for prevention or treatment for the SARS family of coronaviruses, e.g., SARS-CoV-2 and SARS-OC43 (common cold virus), include non-nucleoside reverse transcriptase inhibitors (NNRTI), such as rilpivirine, and nucleoside-analogue antiviral agents, such as remdesivir.