公开(公告)号：US11274282B2

公开(公告)日：2022-03-15

申请号：US16875056

申请日：2020-05-15

Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM

Inventor： Sergio E. Rodriguez ,  Robert W. Cross ,  Chad E. Mire ,  Thomas W. Geisbert

IPC: A61K39/00 ,  A61K39/12 ,  A61K39/23 ,  C12N15/00 ,  C12N15/74 ,  C12N7/00 ,  C07K14/005 ,  A61K39/205 ,  C12N15/86 ,  G01N33/569 ,  A61P31/14

Abstract: Certain embodiments are directed generally to compositions and methods related to recombinant vesicular stomatitis virus vectors (ΔGrVSV) encoding Crimean-Congo Hemorrhagic Fever glycoprotein precursor (CCHFV-GPC) and forming a recombinant vesicular stomatitis virus vector encoding Crimean-Congo Hemorrhagic Fever glycoprotein precursor (ΔGrVSV-CCHFV-GPC).