-
Patent Agency Ranking
1.发明公开公开(公告)号：US20240000961A1
公开(公告)日：2024-01-04
申请号：US18035894
申请日：2021-11-11
Inventor： Kun NA , Da Hye KIM , Min Ji AHN , Na Eun PARK
CPC classification number: A61K47/6851 , A61K47/60 , A61K41/0071 , A61K47/6889 , A61P35/00
Abstract: The present invention relates to a conjugate including an antibody for treating cancer, a linker, and a block copolymer including PEO and PPO, and a conjugate further including a low molecular weight compound. The conjugate has excellent cancer cell targeting ability and can efficiently increase cancer cells by increasing the half-life of the antibody, and thus can be effectively used for treating cancer.
-
公开(公告)号：US20230181737A1
公开(公告)日：2023-06-15
申请号：US17926496
申请日：2021-03-08
Inventor： Kun NA , Sang Hee LEE
CPC classification number: A61K41/0071 , A61P3/04 , A61K47/542 , A61K47/60 , A61K47/61 , A61P3/10 , A61N5/062
Abstract: A fatty acid-biocompatible polymer-photosensitizer conjugate is provided. The conjugate can kill GIP-secreting cells by generating active oxygen upon irradiation with light, and has the effect of increasing insulin, and thus can be effectively used for ameliorating and treating metabolic diseases such as obesity and diabetes.
-
3.发明申请公开(公告)号：US20210369634A1
公开(公告)日：2021-12-02
申请号：US17290773
申请日：2019-11-05
Inventor： Kun NA , Jeongdeok SEO , Dahye KIM , Minji AHN
Abstract: The present invention relates to pH-sensitive carbon nanoparticles, a method of preparing the same, and a drug delivery using the same, and pH-sensitive carbon nanoparticles including imidazole is prepared so that a hydrophobic drug and a photosensitizer material can be encapsulated, drug release is possible under weakly acidic conditions, and thus it can be used as a drug carrier for anticancer treatment, photodynamic therapy, or photomediated anticancer immunotherapy.
-
公开(公告)号：US20210283257A1
公开(公告)日：2021-09-16
申请号：US17277285
申请日：2019-09-20
Inventor： Kun NA , Byeong Nam IM
Abstract: The present invention relates to a polymer complex for recognizing Helicobacter pylori and its uses, and in more detail, a water-soluble polymer-photosensitizer complex in which sialyllactose, which selectively binds to the surface of Helicobacter pylori, is conjugated, has excellent selectivity and binding power to the Helicobacter pylori strain, and the photosensitizer in the complex generates singlet oxygen when irradiated with laser to effectively induce the inactivation of Helicobacter pylori and it is intended to provide the complex as a polymer complex for recognizing Helicobacter pylori to effectively detect Helicobacter pylori in the gastrointestinal tract and to provide a Helicobacter pylori photodynamic therapy to solve the conventional antibiotic resistance problem.
-
公开(公告)号：US20160089455A1
公开(公告)日：2016-03-31
申请号：US14670805
申请日：2015-03-27
Applicant: SNU R&DB FOUNDATION , Institute for Basic Science , The Catholic University of Korea Industry-Academic Cooperation Foundation
Inventor： Taeghwan Hyeon , Kun NA , Daishun LING , Wooram PARK
CPC classification number: C08G69/40 , A61K49/1857 , C08G69/08 , C08G81/00
Abstract: The present invention relates to MRI contrasting agent for contrasting cancer cell which contains ultrafine nanoparticles. More particularly, the present invention is directed to a self-assembled ligand composition comprising a ligand A, which is separated at a specific pH range, and a ligand B of which surface charge changes at a specific pH range, MRI contrast agent for contrasting cancer cell comprising said ligand composition and MRI contrasting nanoparticles, and the methods for preparing them.
Abstract translation: 本发明涉及用于对比含有超细纳米颗粒的癌细胞的MRI对比剂。 更具体地，本发明涉及包含在特定pH范围分离的配体A和在特定pH范围内表面电荷变化的配体B的自组装配体组合物，用于对比癌症的MRI造影剂 包含所述配体组合物和MRI对比纳米颗粒的细胞及其制备方法。
-
-
-
-
Search Results
5
records
(took 0.019 seconds)
