公开(公告)号：US20230271024A1

公开(公告)日：2023-08-31

申请号：US18165916

申请日：2023-02-07

Applicant: THE METHODIST HOSPITAL DBA HOUSTON METHODIST HOSPITAL

Inventor： Santosh Anand Helekar ,  David Stuart Baskin ,  Martyn Alun Sharpe ,  Kumar Pichumani

IPC: A61N2/00 ,  A61N2/06 ,  A61N2/12

CPC classification number: A61N2/004 ,  A61N2/06 ,  A61N2/12

Abstract: To disrupt mitochondrial function in certain cells, controlling hardware causes a magnet to oscillate so as to generate an oscillating magnetic field. The oscillating magnetic field is applied to a volume of tissue including cells with degraded mitochondria to trigger apoptosis in the cells with degraded mitochondria.

公开(公告)号：US20220193436A1

公开(公告)日：2022-06-23

申请号：US17567101

申请日：2021-12-31

Applicant: THE METHODIST HOSPITAL DBA HOUSTON METHODIST HOSPITAL

Inventor： Santosh Anand Helekar ,  David Stuart Baskin ,  Martyn Alun Sharpe ,  Kumar Pichumani

IPC: A61N2/00 ,  A61N2/06 ,  A61N2/12

Abstract: The disclosure provides methods of cancer treatment and apparatus and, more particularly, to non-invasive cancer treatments utilizing oscillating magnetic fields to disrupt mitochondrial function or induce apoptosis or another mechanism of cell death in cancer cells. The disclosure also provides a device for providing an OMF treatment to a subject.

公开(公告)号：US20250135218A1

公开(公告)日：2025-05-01

申请号：US19012544

申请日：2025-01-07

Applicant: THE METHODIST HOSPITAL DBA HOUSTON METHODIST HOSPITAL

Inventor： Santosh Anand Helekar ,  David Stuart Baskin ,  Martyn Alun Sharpe ,  Kumar Pichumani

IPC: A61N2/00 ,  A61K31/19 ,  A61K31/20 ,  A61N2/12

Abstract: To disrupt mitochondrial function in certain cells, controlling hardware causes a magnet to oscillate so as to generate an oscillating magnetic field. The oscillating magnetic field is applied to a volume of tissue including cells with degraded mitochondria to trigger apoptosis in the cells with degraded mitochondria.