公开(公告)号：US20180103921A1

公开(公告)日：2018-04-19

申请号：US15787627

申请日：2017-10-18

Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Inventor： Sung-Cheng Huang ,  Koon-Pong Wong ,  Gary W. Small ,  Jorge R. Barrio

IPC: A61B6/00 ,  A61K51/04 ,  A61B5/055 ,  A61B5/00 ,  A61B6/03 ,  G06T7/00 ,  G06T7/11 ,  G06K9/46

CPC classification number: A61B6/5247 ,  A61B5/0035 ,  A61B5/0042 ,  A61B5/055 ,  A61B5/4064 ,  A61B5/4088 ,  A61B5/7275 ,  A61B6/037 ,  A61B6/501 ,  A61B6/5217 ,  A61K51/04 ,  G06K9/4604 ,  G06K9/62 ,  G06K2209/051 ,  G06T7/0014 ,  G06T7/11 ,  G06T7/30 ,  G06T2207/10088 ,  G06T2207/10104 ,  G06T2207/30016 ,  G16H30/40 ,  G16H50/30 ,  G16H50/50

Abstract: A method of using PET imaging includes using PET images obtained using a radiotracer for the determination of the progressive course of regional brain PET activities for a progressive neurodegenerative disease (e.g., MCI, AD, and CTE). The method may be used for the automatic staging of neurodegenerative disease for a particular patient/subject based on regional intensity and spatial patterns of the brain signals measured by PET imaging. The method may also be used to diagnose or classify the disease of a patient among multiple possibilities based on PET imaging profiles (e.g., for separating or distinguishing CTE from AD).

公开(公告)号：US10357217B2

公开(公告)日：2019-07-23

申请号：US15787627

申请日：2017-10-18

Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

Inventor： Sung-Cheng Huang ,  Koon-Pong Wong ,  Gary W. Small ,  Jorge R. Barrio

IPC: A61B6/00 ,  G06T7/11 ,  A61B5/00 ,  A61B6/03 ,  A61K51/04 ,  G06K9/46 ,  G06T7/00 ,  G06K9/62 ,  G06T7/30 ,  A61B5/055

Abstract: A method of using PET imaging includes using PET images obtained using a radiotracer for the determination of the progressive course of regional brain PET activities for a progressive neurodegenerative disease (e.g., MCI, AD, and CTE). The method may be used for the automatic staging of neurodegenerative disease for a particular patient/subject based on regional intensity and spatial patterns of the brain signals measured by PET imaging. The method may also be used to diagnose or classify the disease of a patient among multiple possibilities based on PET imaging profiles (e.g., for separating or distinguishing CTE from AD).