-
公开(公告)号：US11771745B2
公开(公告)日：2023-10-03
申请号：US17362633
申请日：2021-06-29
Inventor： Jan P. Kraus , Tomas Majtan , Erez Bublil
IPC: A61K38/51 , A61K9/00 , A61K31/198 , A61K31/205 , A61K31/385 , A61K45/06 , A61K47/60 , C12N9/88 , C12N9/96 , A61P19/10 , A61P43/00 , A61P13/02 , A61P17/14 , A61P27/02
CPC classification number: A61K38/51 , A61K9/0019 , A61K31/198 , A61K31/205 , A61K31/385 , A61K45/06 , A61K47/60 , C12N9/88 , C12N9/96 , C12Y402/01022 , A61K2300/00
Abstract: Provided are compositions and methods for enzyme replacement therapy using modified human cystathionine beta synthase (CBS) in the treatment of homocystinuria and related diseases and disorders.
-
2.发明申请公开(公告)号：US20180311325A1
公开(公告)日：2018-11-01
申请号：US16025652
申请日：2018-07-02
Inventor： Jan P. Kraus , Tomas Majtan , Erez Bublil
IPC: A61K38/51 , A61K45/06 , C12N9/88 , C12N9/96 , A61K47/60 , A61K9/00 , A61K31/198 , A61K31/205 , A61K31/385
CPC classification number: A61K38/51 , A61K9/0019 , A61K31/198 , A61K31/205 , A61K31/385 , A61K45/06 , A61K47/60 , C12N9/88 , C12N9/96 , C12Y402/01022 , A61K2300/00
Abstract: The invention provides reagents and methods for enzyme replacement therapy using chemically modified species of human cystathionine β-synthase (CBS) to treat homocystinuria and other related diseases and disorders.
-
3.发明授权Chemically modified cystathionine beta-synthase enzyme for treatment of homocystinuria 有权用于治疗同型胱尿蛋白尿的化学修饰的胱硫醚β-合酶公开(公告)号：US09034318B2
公开(公告)日：2015-05-19
申请号：US13803804
申请日：2013-03-14
Inventor： Jan P Kraus , Tomas Majtan , Erez Bublil
IPC: A61K38/54 , C12N9/96 , C12N9/88 , C07H21/04 , C07K1/00 , A61K38/51 , A61K45/06 , A61K31/198 , A61K31/205 , A61K31/385 , A61K9/00
CPC classification number: A61K38/51 , A61K9/0019 , A61K31/198 , A61K31/205 , A61K31/385 , A61K45/06 , A61K47/60 , C12N9/88 , C12N9/96 , C12Y402/01022 , A61K2300/00
Abstract: The invention provides reagents and methods for enzyme replacement therapy using chemically modified species of human cystathionine β-synthase (CBS) to treat homocystinuria and other related diseases and disorders.
Abstract translation: 本发明提供了使用化学修饰的人类胱硫醚和半胱氨酸（CBS）物质进行酶替代治疗以治疗同胱尿蛋白尿和其它相关疾病和病症的试剂和方法。
-
公开(公告)号：US11077175B2
公开(公告)日：2021-08-03
申请号：US16824931
申请日：2020-03-20
Inventor： Jan P. Kraus , Tomas Majtan , Erez Bublil
IPC: A61K38/51 , A61K47/60 , A61K9/00 , A61K31/198 , A61K31/205 , A61K31/385 , A61K45/06 , C12N9/88 , C12N9/96 , A61P43/00 , A61P27/02 , A61P19/10 , A61P17/14 , A61P13/02
Abstract: Provided are compositions and methods for enzyme replacement therapy using modified human cystathionine beta synthase (CBS) in the treatment of homocystinuria and related diseases and disorders.
-
公开(公告)号：US10265387B2
公开(公告)日：2019-04-23
申请号：US15492671
申请日：2017-04-20
Inventor： Jan P. Kraus , Tomas Majtan , Erez Bublil
IPC: A61K38/51 , C12N9/96 , C12N9/88 , A61K31/205 , A61K47/48
Abstract: Provided herein are improved compositions and methods for enzyme replacement therapy using modified human cystathionine beta synthase (CBS) in the treatment of homocystinuria and related diseases and disorders.
-
Patent Agency Ranking
公开(公告)号：US09675678B2
公开(公告)日：2017-06-13
申请号：US14935690
申请日：2015-11-09
Inventor： Jan P Kraus , Tomas Majtan , Erez Bublil
IPC: A61K38/54 , A61K38/00 , C12N9/96 , C12N9/88 , C07H21/04 , C07K1/00 , A61K38/51 , A61K31/205 , A61K47/48 , A61K9/00 , A61K45/06 , A61K31/198 , A61K31/385
CPC classification number: A61K38/51 , A61K9/0019 , A61K31/205 , A61K45/06 , A61K47/60 , C12N9/88 , C12N9/96 , C12Y402/01022 , A61K31/198 , A61K2300/00 , A61K31/385
Abstract: Provided herein are improved compositions and methods for enzyme replacement therapy using modified human cystathionine beta synthase (CBS) in the treatment of homocystinuria and related diseases and disorders.
-
公开(公告)号：US20220125896A1
公开(公告)日：2022-04-28
申请号：US17362633
申请日：2021-06-29
Inventor： Jan P. Kraus , Tomas Majtan , Erez Bublil
IPC: A61K38/51 , A61K47/60 , A61K9/00 , A61K31/198 , A61K31/205 , A61K31/385 , A61K45/06 , C12N9/88 , C12N9/96
Abstract: Provided are compositions and methods for enzyme replacement therapy using modified human cystathionine beta synthase (CBS) in the treatment of homocystinuria and related diseases and disorders.
-
公开(公告)号：US20200276282A1
公开(公告)日：2020-09-03
申请号：US16824931
申请日：2020-03-20
Inventor： Jan P. Kraus , Tomas Majtan , Erez Bublil
IPC: A61K38/51 , A61K31/205 , A61K47/60 , A61K9/00 , A61K45/06 , C12N9/88 , C12N9/96 , A61K31/198 , A61K31/385
Abstract: Provided are compositions and methods for enzyme replacement therapy using modified human cystathionine beta synthase (CBS) in the treatment of homocystinuria and related diseases and disorders.
-
公开(公告)号：US10653755B2
公开(公告)日：2020-05-19
申请号：US15774755
申请日：2016-11-09
Inventor： Jan P. Kraus , Tomas Majtan , Erez Bublil
IPC: A61K38/51 , A61K31/385 , A61K31/198 , A61K47/60 , C12N9/96 , C12N9/88 , A61K45/06 , A61K9/00 , A61K31/205
Abstract: Provided are compositions and methods for enzyme replacement therapy using modified human cystathionine beta synthase (CBS) in the treatment of homocystinuria and related diseases and disorders.
-
公开(公告)号：US20180318404A1
公开(公告)日：2018-11-08
申请号：US15774755
申请日：2016-11-09
Inventor： Jan P. Kraus , Tomas Majtan , Erez Bublil
IPC: A61K38/51 , A61K31/205 , A61K47/60 , C12N9/96 , A61K9/00 , A61K45/06 , C12N9/88 , A61K31/198 , A61K31/385
CPC classification number: A61K38/51 , A61K9/0019 , A61K31/198 , A61K31/205 , A61K31/385 , A61K45/06 , A61K47/48215 , A61K47/60 , A61K2300/00 , C12N9/88 , C12N9/96 , C12Y402/01022
Abstract: Provided are compositions and methods for enzyme replacement therapy using modified human cystathionine beta synthase (CBS) in the treatment of homocystinuria and related diseases and disorders.
-
-
-
-
-
-
-
-
-
Search Results
19
records
(took 0.02 seconds)
