公开(公告)号：US20240233873A9

公开(公告)日：2024-07-11

申请号：US18547705

申请日：2022-02-24

Applicant: THE SCRIPPS RESEARCH INSTITUTE

Inventor： Andrew B. Ward ,  Aleksandar Antanasijevic ,  Charles Bowman ,  Christopher Cottrell ,  Gabriel Ozorowski ,  Robert Kirchdoerfer

IPC: G16B30/10 ,  G01N33/577

CPC classification number: G16B30/10 ,  G01N33/577

Abstract: Provided herein are methods for discovery of epitope specific monoclonal antibodies to pathogens directly from immune sera for immunotherapeutic use. Further provided herein are methods to determine molecular structure of antibodies targeting an antigen from convalescent or vaccinated individuals for the purpose of rational vaccine design.

公开(公告)号：US20240136019A1

公开(公告)日：2024-04-25

申请号：US18547705

申请日：2022-02-24

Applicant: THE SCRIPPS RESEARCH INSTITUTE

Inventor： Andrew B. Ward ,  Aleksandar Antanasijevic ,  Charles Bowman ,  Christopher Cottrell ,  Gabriel Ozorowski ,  Robert Kirchdoerfer

IPC: G16B30/10 ,  G01N33/577

CPC classification number: G16B30/10 ,  G01N33/577

Abstract: Provided herein are methods for discovery of epitope specific monoclonal antibodies to pathogens directly from immune sera for immunotherapeutic use. Further provided herein are methods to determine molecular structure of antibodies targeting an antigen from convalescent or vaccinated individuals for the purpose of rational vaccine design.