公开(公告)号：US20240417426A1

公开(公告)日：2024-12-19

申请号：US18672712

申请日：2024-05-23

Applicant: THE UAB RESEARCH FOUNDATION

Inventor： Dmitry Vassylyev ,  Norman Patrick Higgins ,  Marina Vassylyeva ,  Alexey Vasiliev

IPC: C07K1/22 ,  C07K14/245 ,  C12N9/22 ,  C12N15/62 ,  C12P21/02 ,  C12P21/06

Abstract: Provided herein are compositions and methods for protein purification.

公开(公告)号：US20180371010A1

公开(公告)日：2018-12-27

申请号：US16060753

申请日：2016-12-09

Applicant: THE UAB RESEARCH FOUNDATION

Inventor： Dmitry Vassylyev ,  Norman Patrick Higgins ,  Marina Vassylyeva ,  Alexey Vasiliev

IPC: C07K1/22 ,  C07K14/245 ,  C12N9/22 ,  C12P21/02

Abstract: Provided herein are compositions and methods for protein purification.

公开(公告)号：US12030913B2

公开(公告)日：2024-07-09

申请号：US16938377

申请日：2020-07-24

Applicant: THE UAB RESEARCH FOUNDATION

Inventor： Dmitry Vassylyev ,  Norman Patrick Higgins ,  Marina Vassylyeva ,  Alexey Vasiliev

IPC: C07K1/22 ,  C07K14/245 ,  C12N9/22 ,  C12N15/62 ,  C12P21/02 ,  C12P21/06

CPC classification number: C07K1/22 ,  C07K14/245 ,  C12N9/22 ,  C12N15/62 ,  C12P21/02 ,  C12P21/06 ,  C07K2319/00 ,  C07K2319/21 ,  C07K2319/23 ,  C07K2319/24 ,  C07K2319/50 ,  C12N2310/20

Abstract: Compositions comprising colicin immunity proteins and methods of using same for protein purification are described.

公开(公告)号：US20210009633A1

公开(公告)日：2021-01-14

申请号：US16938377

申请日：2020-07-24

Applicant: THE UAB RESEARCH FOUNDATION

Inventor： Dmitry Vassylyev ,  Norman Patrick Higgins ,  Marina Vassylyeva ,  Alexey Vasiliev

IPC: C07K1/22 ,  C07K14/245 ,  C12P21/02 ,  C12N9/22 ,  C12P21/06 ,  C12N15/62

Abstract: Provided herein are compositions and methods for protein purification.

公开(公告)号：US10759830B2

公开(公告)日：2020-09-01

申请号：US16060753

申请日：2016-12-09

Applicant: THE UAB RESEARCH FOUNDATION

Inventor： Dmitry Vassylyev ,  Norman Patrick Higgins ,  Marina Vassylyeva ,  Alexey Vasiliev

IPC: C12N15/62 ,  C07K1/22 ,  C07K14/245 ,  C12P21/02 ,  C12N9/22 ,  C12P21/06

Abstract: The disclosure provides compositions and methods for purification of proteins, including multi-subunit complexes and membrane proteins. Modified colicin-DNAse domains and modified colicin immunity proteins are provided for use in purification methods. Also provided are related nucleic acids, vectors, genetically modified cells and affinity matrices.