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公开(公告)号：US11945857B2
公开(公告)日：2024-04-02
申请号：US17126396
申请日：2020-12-18
CPC分类号： C07K16/1278 , C07K16/1018 , C07K16/1063 , C07K16/34 , C07K2317/14 , C07K2317/20 , C07K2317/33 , C07K2317/35 , C07K2317/76
摘要： Disclosed are compositions and methods related to variable lymphocyte receptors (VLRs). More particularly, disclosed are a variety of antigen specific polypeptides, including soluble, monoclonal, and multivalent forms, as well as methods of using the polypeptides, antibodies that bind the antigen specific polypeptides, and nucleic acids, vectors and expression systems that encode the polypeptides. Antigen specific polypeptides that selectively bind pathogens, like anthrax, and carbohydrates, like blood group determinants, are specifically disclosed.
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公开(公告)号：US10239936B2
公开(公告)日：2019-03-26
申请号：US15052986
申请日：2016-02-25
摘要： Disclosed are compositions and methods related to variable lymphocyte receptors (VLRs). More particularly, disclosed are a variety of antigen specific polypeptides, including soluble, monoclonal, and multivalent forms, as well as methods of using the polypeptides, antibodies that bind the antigen specific polypeptides, and nucleic acids, vectors and expression systems that encode the polypeptides. Antigen specific polypeptides that selectively bind pathogens, like anthrax, and carbohydrates, like blood group determinants, are specifically disclosed.
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公开(公告)号：US20210253676A1
公开(公告)日：2021-08-19
申请号：US17126396
申请日：2020-12-18
摘要： Disclosed are compositions and methods related to variable lymphocyte receptors (VLRs). More particularly, disclosed are a variety of antigen specific polypeptides, including soluble, monoclonal, and multivalent forms, as well as methods of using the polypeptides, antibodies that bind the antigen specific polypeptides, and nucleic acids, vectors and expression systems that encode the polypeptides. Antigen specific polypeptides that selectively bind pathogens, like anthrax, and carbohydrates, like blood group determinants, are specifically disclosed.
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4.发明申请公开(公告)号：US20190202897A1
公开(公告)日：2019-07-04
申请号：US16265437
申请日：2019-02-01
CPC分类号： C07K16/1278 , C07K16/1018 , C07K16/1063 , C07K16/34 , C07K2317/14 , C07K2317/20 , C07K2317/33 , C07K2317/35 , C07K2317/76
摘要： Disclosed are compositions and methods related to variable lymphocyte receptors (VLRs). More particularly, disclosed are a variety of antigen specific polypeptides, including soluble, monoclonal, and multivalent forms, as well as methods of using the polypeptides, antibodies that bind the antigen specific polypeptides, and nucleic acids, vectors and expression systems that encode the polypeptides. Antigen specific polypeptides that selectively bind pathogens, like anthrax, and carbohydrates, like blood group determinants, are specifically disclosed.
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5.发明申请METHODS AND COMPOSITIONS RELATED TO SOLUBLE MONOCLONAL VARIABLE LYMPHOCYTE RECEPTORS OF DEFINED ANTIGEN SPECIFICITY 审中-公开与可溶性单稳态淋巴细胞受体相关的定义抗原特异性的方法和组合物公开(公告)号：US20160376348A1
公开(公告)日：2016-12-29
申请号：US15052986
申请日：2016-02-25
CPC分类号： C07K16/1278 , C07K16/1018 , C07K16/1063 , C07K16/34 , C07K2317/14 , C07K2317/20 , C07K2317/33 , C07K2317/35 , C07K2317/76
摘要： Disclosed are compositions and methods related to variable lymphocyte receptors (VLRs). More particularly, disclosed are a variety of antigen specific polypeptides, including soluble, monoclonal, and multivalent forms, as well as methods of using the polypeptides, antibodies that bind the antigen specific polypeptides, and nucleic acids, vectors and expression systems that encode the polypeptides. Antigen specific polypeptides that selectively bind pathogens, like anthrax, and carbohydrates, like blood group determinants, are specifically disclosed.
摘要翻译： 公开了与可变淋巴细胞受体（VLR）相关的组合物和方法。 更具体地，公开了多种抗原特异性多肽，包括可溶性，单克隆和多价形式，以及使用多肽，结合抗原特异性多肽的抗体以及编码多肽的核酸，载体和表达系统 。 具体公开了选择性结合病原体（如炭疽）和碳水化合物（如血型决定簇）的抗原特异性多肽。
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