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公开(公告)号:US10561708B2
公开(公告)日:2020-02-18
申请号:US15975396
申请日:2018-05-09
IPC分类号: A61K38/17 , A61K31/506 , A61K45/06
摘要: Compositions, kits and methods for treating cancer in a subject in need thereof are disclosed involving one or more inhibitors of the JAK/STAT pathway which renders the cancer chemosensitive and/or radiosensitive.
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公开(公告)号:US20170298362A1
公开(公告)日:2017-10-19
申请号:US15636952
申请日:2017-06-29
IPC分类号: C12N15/113 , A61K31/713 , A61K31/506 , C12Q1/68 , A61K31/519 , A61K45/06
CPC分类号: C12N15/1137 , A61K31/506 , A61K31/519 , A61K31/713 , A61K45/06 , C12N15/113 , C12N2310/14 , C12N2320/12 , C12N2320/30 , C12Q1/6886 , C12Q2600/136 , C12Q2600/158
摘要: Panels, compositions, and methods for treating cancer in a subject in need thereof are disclosed involving one or more genes the suppression of which renders the cancer chemosensitive and/or radiosensitive.
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公开(公告)号:US20130150258A1
公开(公告)日:2013-06-13
申请号:US13734527
申请日:2013-01-04
IPC分类号: C12Q1/68
CPC分类号: C12Q1/6886 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , G01N33/57407 , G01N33/57484 , G01N2800/52
摘要: Disclosed is a set of genes differentially expressed in chemotherapy and radiation resistant tumors useful in predicting response to therapy and assessing risk of local-regional failure, survival and metastasis in cancer patients. Also disclosed are methods for characterizing tumors according to gene expression and kits for use in the methods of the invention.
摘要翻译: 公开了一组在化学疗法和耐辐射肿瘤中差异表达的基因,可用于预测治疗反应和评估癌症患者局部局部衰竭,存活和转移的风险。 还公开了根据基因表达表征肿瘤的方法和用于本发明方法的试剂盒。
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公开(公告)号:US10421971B2
公开(公告)日:2019-09-24
申请号:US15109945
申请日:2014-10-24
发明人: Liufu Deng , Yang-xin Fu , Nikolai Khodarev , Ralph Weichselbaum
IPC分类号: A61K31/713 , C12N15/113 , A61K45/06 , A61K31/7084 , A61K31/7088 , A61K41/00 , A61N5/10
摘要: Compositions, kits and methods for treating cancer in a subject in need thereof are disclosed involving one or more genes the suppression of which renders the cancer chemosensitive and/or radiosensitive.
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公开(公告)号:US20180256678A1
公开(公告)日:2018-09-13
申请号:US15975396
申请日:2018-05-09
IPC分类号: A61K38/17 , A61K45/06 , A61K31/506
CPC分类号: A61K38/177 , A61K31/506 , A61K45/06
摘要: Compositions, kits and methods for treating cancer in a subject in need thereof are disclosed involving one or more inhibitors of the JAK/STAT pathway which renders the cancer chemosensitive and/or radiosensitive.
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公开(公告)号:US20160333355A1
公开(公告)日:2016-11-17
申请号:US15109945
申请日:2014-10-24
发明人: Liufu Deng , Yang-xin Fu , Nikolai Khodarev , Ralph Weichselbaum
IPC分类号: C12N15/113 , A61N5/10 , A61K31/7084 , A61K31/7088 , A61K41/00 , A61K45/06
摘要: Compositions, kits and methods for treating cancer in a subject in need thereof are disclosed involving one or more genes the suppression of which renders the cancer chemosensitive and/or radiosensitive.
摘要翻译: 公开了用于治疗有需要的受试者中的癌症的组合物,试剂盒和方法,其涉及抑制其使癌症化学敏感和/或辐射敏感的一个或多个基因。
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公开(公告)号:US20190071679A1
公开(公告)日:2019-03-07
申请号:US16179577
申请日:2018-11-02
IPC分类号: C12N15/113 , A61K45/06 , C12Q1/6886 , A61K31/713 , A61K31/506 , A61K31/519
摘要: Panels, compositions, and methods for treating cancer in a subject in need thereof are disclosed involving one or more genes the suppression of which renders the cancer chemosensitive and/or radiosensitive.
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