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公开(公告)号：US09250232B2
公开(公告)日：2016-02-02
申请号：US14378022
申请日：2013-02-15
Applicant: THE UNIVERSITY OF TOKYO
Inventor： Tetsuo Nagano , Kenjiro Hanaoka , Kazuhisa Hirabayashi , Yuko Toki
CPC classification number: G01N33/52 , C07F7/0816 , C07H17/04 , C07H23/00 , C12Q1/00
Abstract: A compound represented by the formula (I) [R1 represents hydrogen atom or a substituent; R2, R3, R6, and R7 represent hydrogen atom, an alkyl group, a halogen atom, or a hydrophilic substituent; R4 and R5 represent an alkyl group or an aryl group; R8 and R9 represent a group cleaved by contact with an object substance for measurement; and X represents silicon atom, germanium atom, or tin atom] or a salt thereof, which is useful as a fluorescent probe that emits red fluorescence by contact with an object substance for measurement.
Abstract translation: 由式（I）表示的化合物[R 1表示氢原子或取代基; R2，R3，R6和R7表示氢原子，烷基，卤素原子或亲水取代基; R4和R5代表烷基或芳基; R8和R9表示与用于测量的物质接触而断裂的基团; X表示硅原子，锗原子或锡原子）或其盐，其可用作通过与测量对象物质接触而发出红色荧光的荧光探针。
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公开(公告)号：US20150212073A1
公开(公告)日：2015-07-30
申请号：US14378022
申请日：2013-02-15
Applicant: THE UNIVERSITY OF TOKYO
Inventor： Tetsuo Nagano , Kenjiro Hanaoka , Kazuhisa Hirabayashi , Yuko Toki
CPC classification number: G01N33/52 , C07F7/0816 , C07H17/04 , C07H23/00 , C12Q1/00
Abstract: A compound represented by the formula (I) [R1 represents hydrogen atom or a substituent; R2, R3, R6, and R7 represent hydrogen atom, an alkyl group, a halogen atom, or a hydrophilic substituent; R4 and R5 represent an alkyl group or an aryl group; R8 and R9 represent a group cleaved by contact with an object substance for measurement; and X represents silicon atom, germanium atom, or tin atom] or a salt thereof, which is useful as a fluorescent probe that emits red fluorescence by contact with an object substance for measurement.
Abstract translation: 由式（I）表示的化合物[R 1表示氢原子或取代基; R2，R3，R6和R7表示氢原子，烷基，卤素原子或亲水取代基; R4和R5代表烷基或芳基; R8和R9表示与用于测量的物质接触而断裂的基团; X表示硅原子，锗原子或锡原子）或其盐，其可用作通过与测量对象物质接触而发出红色荧光的荧光探针。
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