公开(公告)号：US09751848B2

公开(公告)日：2017-09-05

申请号：US15302936

申请日：2015-09-28

申请人： THOMAS SWAN & CO. LTD

发明人： David Dunn ,  Howard Winston Tyrrell Sutton ,  John Ing Chuan Daly ,  Simon Jonathon Grant ,  Lian Hutchings ,  Patrice Georges Antonin Ribiere ,  Matthew Richard Gibbings ,  Sergio Aaron Gamboa Martinez ,  Craig Anderson ,  Yulia Rogan

IPC分类号： C07D315/00 ,  C07D307/12 ,  B01J23/58

CPC分类号： C07D307/12 ,  B01J23/58

摘要： A catalyst, method of using, and use of a hydrogenation catalyst, preferably palladium on a support, preferably alumina or activated charcoal support. This in the presence of lithium salts, with salts such as the borates being preferred. This provides hydrogenation of precursors to give rise to a stereoselective, such as diastereoselective bias in the product of alkene hydrogenation using the catalyst.This equation, using the preferred substrate, best illustrates the invention:

公开(公告)号：US20170197929A1

公开(公告)日：2017-07-13

申请号：US15470691

申请日：2017-03-27

申请人： THOMAS SWAN & CO. LTD

发明人： David Dunn ,  Howard Winston Tyrrell Sutton ,  John Ing Chuan Daly ,  Simon Jonathon Grant ,  Lian Hutchings ,  Patrice Georges Antonin Ribiere ,  Matthew Richard Gibbings ,  Sergio Aaron Gamboa Martinez ,  Craig Anderson ,  Yulia Rogan

IPC分类号： C07D307/12 ,  B01J23/58

CPC分类号： C07D307/12 ,  B01J23/58

摘要： A catalyst, method of using, and use of a hydrogenation catalyst, preferably palladium on a support, preferably alumina or activated charcoal support. This in the presence of lithium salts, with salts such as the borates being preferred. This provides hydrogenation of precursors to give rise to a stereoselective, such as diastereoselective bias in the product of alkene hydrogenation using the catalyst.This equation, using the preferred substrate, best illustrates the invention:

公开(公告)号：US10000460B2

公开(公告)日：2018-06-19

申请号：US15470691

申请日：2017-03-27

申请人： THOMAS SWAN & CO. LTD

发明人： David Dunn ,  Howard Winston Tyrrell Sutton ,  John Ing Chuan Daly ,  Simon Jonathon Grant ,  Lian Hutchings ,  Patrice Georges Antonin Ribiere ,  Matthew Richard Gibbings ,  Sergio Aaron Gamboa Martinez ,  Craig Anderson ,  Yulia Rogan

IPC分类号： C07D307/02 ,  B01J23/58 ,  C07D307/12

CPC分类号： C07D307/12 ,  B01J23/58

摘要： A hydrogenation catalyst, preferably palladium on a support, preferably alumina or activated charcoal support, is used in the presence of lithium salts, with salts such as the borates being preferred. This provides hydrogenation of precursors to give rise to a stereoselective, such as diastereoselective bias in the product of alkene hydrogenation using the catalyst.