公开(公告)号：US20250115906A1

公开(公告)日：2025-04-10

申请号：US18727149

申请日：2023-01-12

Applicant: TOOLGEN INCORPORATED

Inventor： Dong Woo SONG ,  Hyerim LEE ,  Hye-Kyung OH ,  Beom Seok CHOI ,  Kyu Jun LEE ,  Nan Yeong GO ,  Jae Young LEE

IPC: C12N15/113 ,  C12N9/22 ,  C12N15/11 ,  C12N15/86

Abstract: The present invention relates to a Schwann cell-specific promoter and use thereof. More particularly, the present invention relates to an artificially engineered minimal promoter that specifically operates in Schwann cells, wherein the artificially engineered minimal promoter is derived from an MPZ (Myelin Protein Zero or PO) promoter. In addition, the present invention relates to a vector using the Schwann cell-specific promoter and a method for treating Schwann cell-related diseases using same.