公开(公告)号：US20190276503A1

公开(公告)日：2019-09-12

申请号：US16349672

申请日：2017-09-28

Applicant: TOOLGEN INCORPORATED

Inventor： Seok Joong KIM ,  Dong Woo SONG ,  Young Bin HONG ,  Byung Ok CHOI ,  Jae Young LEE ,  Jung Min LEE

IPC: C07K14/315 ,  C12N15/86 ,  A61K35/30

Abstract: The present invention relates to an artificially manipulated SC function-controlling factor for SC function control and/or the treatment or alleviation of a disease due to an SC function disorder, and to a use thereof. More specifically, the present invention relates to a system capable of performing artificial SC function control and/or treating or alleviating a disease due to an SC function disorder, the system comprising: an artificially manipulated SC function-controlling factor for SC function control and/or the treatment or alleviation of a disease due to an SC function disorder; and/or a composition for treating or alleviating a disease due to an SC function disorder. In a specific aspect, the present invention relates to an SC function-controlling system by an SC function-controlling factor, such as artificially manipulated PMP22, and/or an expression product thereof.